Sputum culture conversion as a prognostic marker for end-of-treatment outcome in patients with multidrug-resistant tuberculosis: a secondary analysis of data from two observational cohort studies

Sputum culture conversion is often used as an early microbiological endpoint in phase 2 clinical trials of tuberculosis treatment on the basis of its assumed predictive value for end-of-treatment outcome, particularly in patients with drug-susceptible tuberculosis. We aimed to assess the validity of...

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Published in:	The lancet respiratory medicine Vol. 3; no. 3; pp. 201 - 209
Main Authors:	Kurbatova, Ekaterina V, Cegielski, J Peter, Lienhardt, Christian, Akksilp, Rattanawadee, Bayona, Jaime, Becerra, Mercedes C, Caoili, Janice, Contreras, Carmen, Dalton, Tracy, Danilovits, Manfred, Demikhova, Olga V, Ershova, Julia, Gammino, Victoria M, Gelmanova, Irina, Heilig, Charles M, Jou, Ruwen, Kazennyy, Boris, Keshavjee, Salmaan, Kim, Hee Jin, Kliiman, Kai, Kvasnovsky, Charlotte, Leimane, Vaira, Mitnick, Carole D, Quelapio, Imelda, Riekstina, Vija, Smith, Sarah E, Tupasi, Thelma, van der Walt, Martie, Vasilyeva, Irina A, Via, Laura E, Viiklepp, Piret, Volchenkov, Grigory, Walker, Allison Taylor, Wolfgang, Melanie, Yagui, Martin, Zignol, Matteo
Format:	Journal Article
Language:	English
Published:	England 01.03.2015
Subjects:	Adolescent Adult Aged Humans Middle Aged Mycobacterium tuberculosis - isolation & purification Prospective Studies Sputum - microbiology Treatment Outcome Tuberculosis, Multidrug-Resistant - drug therapy Tuberculosis, Pulmonary - drug therapy Young Adult
ISSN:	2213-2619
Online Access:	Get more information
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