Cellular inhibitors with Fv1-like activity restrict human and simian immunodeficiency virus tropism

Many nonhuman primate cells are unable to support the replication of HIV-1, whereas others are nonpermissive for infection by simian immunodeficiency virus from macaques (SIVmac). Here, we show that restricted HIV-1 and SIVmac infection of primate cell lines shares some salient features with Fv1 and...

Full description

Bibliographic Details

Published in:	Proceedings of the National Academy of Sciences - PNAS Vol. 99; no. 18; p. 11914
Main Authors:	Cowan, Simone, Hatziioannou, Theodora, Cunningham, Tshaka, Muesing, Mark A, Gottlinger, Heinrich G, Bieniasz, Paul D
Format:	Journal Article
Language:	English
Published:	United States 03.09.2002
Subjects:	Animals Antiviral Agents Cell Line HIV-1 - physiology Humans Proteins - physiology Simian Immunodeficiency Virus - physiology Transcription, Genetic Tropism Virus Replication
ISSN:	0027-8424
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!