Evidence of Polygenic Adaptation in Sardinia at Height-Associated Loci Ascertained from the Biobank Japan

Adult height is one of the earliest putative examples of polygenic adaptation in humans. However, this conclusion was recently challenged because residual uncorrected stratification from large-scale consortium studies was considered responsible for the previously noted genetic difference. It thus re...

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Vydané v:	American journal of human genetics Ročník 107; číslo 1; s. 60
Hlavní autori:	Chen, Minhui, Sidore, Carlo, Akiyama, Masato, Ishigaki, Kazuyoshi, Kamatani, Yoichiro, Schlessinger, David, Cucca, Francesco, Okada, Yukinori, Chiang, Charleston W K
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 02.07.2020
Predmet:	Adaptation, Physiological - genetics Alleles Asian People - genetics Biological Specimen Banks Body Height - genetics Genetics, Population - methods Genome, Human - genetics Genome-Wide Association Study - methods Haplotypes - genetics Humans Italy Japan Multifactorial Inheritance - genetics Phenotype Polymorphism, Single Nucleotide - genetics Selection, Genetic - genetics White People - genetics Italy Japan population stratification polygenic adaptation height
ISSN:	1537-6605, 1537-6605
On-line prístup:	Zistit podrobnosti o prístupe
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