Consensus recommendations for trabecular meshwork cell isolation, characterization and culture

Cultured trabecular meshwork (TM) cells are a valuable model system to study the cellular mechanisms involved in the regulation of conventional outflow resistance and thus intraocular pressure; and their dysfunction resulting in ocular hypertension. In this review, we describe the standard procedure...

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Published in:Experimental eye research Vol. 171; pp. 164 - 173
Main Authors: Keller, Kate E., Bhattacharya, Sanjoy K., Borrás, Theresa, Brunner, Thomas M., Chansangpetch, Sunee, Clark, Abbott F., Dismuke, W. Michael, Du, Yiqin, Elliott, Michael H., Ethier, C. Ross, Faralli, Jennifer A., Freddo, Thomas F., Fuchshofer, Rudolf, Giovingo, Michael, Gong, Haiyan, Gonzalez, Pedro, Huang, Alex, Johnstone, Murray A., Kaufman, Paul L., Kelley, Mary J., Knepper, Paul A., Kopczynski, Casey C., Kuchtey, John G., Kuchtey, Rachel W., Kuehn, Markus H., Lieberman, Raquel L., Lin, Shan C., Liton, Paloma, Liu, Yutao, Lütjen-Drecoll, Elke, Mao, Weiming, Masis-Solano, Marisse, McDonnell, Fiona, McDowell, Colleen M., Overby, Darryl R., Pattabiraman, Padmanabhan P., Raghunathan, Vijay K., Rao, P. Vasanth, Rhee, Douglas J., Chowdhury, Uttio Roy, Russell, Paul, Samples, John R., Schwartz, Donald, Stubbs, Evan B., Tamm, Ernst R., Tan, James C., Toris, Carol B., Torrejon, Karen Y., Vranka, Janice A., Wirtz, Mary K., Yorio, Thomas, Zhang, Jie, Zode, Gulab S., Fautsch, Michael P., Peters, Donna M., Acott, Ted S., Stamer, W. Daniel
Format: Journal Article
Language:English
Published: England Elsevier Ltd 01.06.2018
Subjects:
Age Factors
Animals
Aqueous humor dynamics
Biomarkers - metabolism
Cell Culture Techniques
Cell Separation - methods
Consensus
Conventional outflow
Fetus
Glaucoma
Guidelines as Topic
Humans
Intraocular pressure
Ocular hypertension
Tissue and Organ Harvesting
Tissue Donors
Tissue Preservation
Trabecular Meshwork - cytology
Trabecular Meshwork - metabolism
Glaucoma
Conventional outflow
Fibroblast growth factor
Phosphate-buffered saline
Interleukin
Ocular hypertension
Matrix gla protein
Fetal bovine serum
Dulbecco's modified Eagle's medium
Ethylenediaminetetraacetic acid
Juxtacanalicular tissue
Trabecular meshwork
Aqueous humor dynamics
Tumor necrosis factor
Schlemm's canal
Dimethyl sulfoxide
Institutional review board
Human immunodeficiency virus
Intraocular pressure
ISSN:0014-4835, 1096-0007, 1096-0007
Online Access:Get full text
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Abstract Cultured trabecular meshwork (TM) cells are a valuable model system to study the cellular mechanisms involved in the regulation of conventional outflow resistance and thus intraocular pressure; and their dysfunction resulting in ocular hypertension. In this review, we describe the standard procedures used for the isolation of TM cells from several animal species including humans, and the methods used to validate their identity. Having a set of standard practices for TM cells will increase the scientific rigor when used as a model, and enable other researchers to replicate and build upon previous findings. •Comprehensive review of techniques to culture TM cells are presented.•Helpful tips for culturing TM cells are described.•First set of consensus standards for TM cell research is defined.
AbstractList Cultured trabecular meshwork (TM) cells are a valuable model system to study the cellular mechanisms involved in the regulation of conventional outflow resistance and thus intraocular pressure; and their dysfunction resulting in ocular hypertension. In this review, we describe the standard procedures used for the isolation of TM cells from several animal species including humans, and the methods used to validate their identity. Having a set of standard practices for TM cells will increase the scientific rigor when used as a model, and enable other researchers to replicate and build upon previous findings.
Cultured trabecular meshwork (TM) cells are a valuable model system to study the cellular mechanisms involved in the regulation of conventional outflow resistance and thus intraocular pressure; and their dysfunction resulting in ocular hypertension. In this review, we describe the standard procedures used for the isolation of TM cells from several animal species including humans, and the methods used to validate their identity. Having a set of standard practices for TM cells will increase the scientific rigor when used as a model, and enable other researchers to replicate and build upon previous findings. •Comprehensive review of techniques to culture TM cells are presented.•Helpful tips for culturing TM cells are described.•First set of consensus standards for TM cell research is defined.
Cultured trabecular meshwork (TM) cells are a valuable model system to study the cellular mechanisms involved in the regulation of conventional outflow resistance and thus intraocular pressure; and their dysfunction resulting in ocular hypertension. In this review, we describe the standard procedures used for the isolation of TM cells from several animal species including humans, and the methods used to validate their identity. Having a set of standard practices for TM cells will increase the scientific rigor when used as a model, and enable other researchers to replicate and build upon previous findings.Cultured trabecular meshwork (TM) cells are a valuable model system to study the cellular mechanisms involved in the regulation of conventional outflow resistance and thus intraocular pressure; and their dysfunction resulting in ocular hypertension. In this review, we describe the standard procedures used for the isolation of TM cells from several animal species including humans, and the methods used to validate their identity. Having a set of standard practices for TM cells will increase the scientific rigor when used as a model, and enable other researchers to replicate and build upon previous findings.
Author Freddo, Thomas F.
Schwartz, Donald
Wirtz, Mary K.
Kuchtey, John G.
Kelley, Mary J.
McDonnell, Fiona
Ethier, C. Ross
Johnstone, Murray A.
Rao, P. Vasanth
Russell, Paul
Elliott, Michael H.
Stamer, W. Daniel
Pattabiraman, Padmanabhan P.
Chowdhury, Uttio Roy
Mao, Weiming
Tamm, Ernst R.
Chansangpetch, Sunee
Giovingo, Michael
Tan, James C.
Bhattacharya, Sanjoy K.
Lin, Shan C.
McDowell, Colleen M.
Lütjen-Drecoll, Elke
Overby, Darryl R.
Rhee, Douglas J.
Gonzalez, Pedro
Kopczynski, Casey C.
Du, Yiqin
Toris, Carol B.
Zhang, Jie
Masis-Solano, Marisse
Knepper, Paul A.
Keller, Kate E.
Dismuke, W. Michael
Fuchshofer, Rudolf
Torrejon, Karen Y.
Yorio, Thomas
Gong, Haiyan
Brunner, Thomas M.
Samples, John R.
Acott, Ted S.
Huang, Alex
Zode, Gulab S.
Faralli, Jennifer A.
Liton, Paloma
Kuehn, Markus H.
Kaufman, Paul L.
Vranka, Janice A.
Clark, Abbott F.
Kuchtey, Rachel W.
Liu, Yutao
Peters, Donna M.
Lieberman, Raquel L.
Raghunathan, Vijay K.
Stubbs, Evan B.
Fautsch, Michael P.
Borrás, Theresa
AuthorAffiliation m University of Regensburg, Germany
t Vanderbilt University, United States
ff University of Southern California, United States
x Imperial College, London, United Kingdom
z University of Houston, United States
kk Department of Ophthalmology, Duke University, DUMC 3802, Durham, NC 27705, United States
ii Department of Pathology & Laboratory Medicine, University of Wisconsin, 1300 University Ave, Madison, WI 53706, United States
i University of Oklahoma, United States
bb University of California, Davis, United States
n John H. Stroger, Jr. Hospital of Cook County, United States
e University of California, San Francisco, United States
p Duke University, United States
gg Glauconix, United States
g Aerie Pharmaceuticals, United States
k University of Wisconsin, United States
y Case Western Reserve University, United States
b University of Miami, United States
w University of Erlangen-Nuremberg, Germany
jj Department of Ophthalmology, Department of Biochemistry & Molecular Biology, Oregon Health and Science Un
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– name: kk Department of Ophthalmology, Duke University, DUMC 3802, Durham, NC 27705, United States
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/29526795$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1167/iovs.13-12033
10.1016/0042-6989(81)90151-6
10.1002/(SICI)1097-0029(19960301)33:4<336::AID-JEMT4>3.0.CO;2-N
10.1016/j.exer.2010.09.017
10.1007/BF00419354
10.1371/journal.pone.0150694
10.18632/oncotarget.3798
10.1016/S0014-4835(82)80074-2
10.1167/iovs.11-7563
10.1016/j.preteyeres.2012.10.004
10.1167/iovs.15-18958
10.1093/hmg/10.2.117
10.1007/s00232-012-9517-4
10.1016/0014-4835(91)90020-F
10.1016/j.exer.2003.07.008
10.1016/0014-4835(91)90032-A
10.1172/JCI109799
10.1167/iovs.06-1403
10.1167/iovs.05-0292
10.5115/acb.2013.46.1.49
10.1167/iovs.11-9134
10.3109/02713689508998409
10.1371/journal.pone.0169671
10.1167/iovs.03-0213
10.1016/S1350-9462(98)00011-1
10.1097/00061198-199506000-00007
10.1080/02713680601107058
10.1016/j.exer.2016.07.009
10.1016/j.exer.2008.10.024
10.3109/02713689409042398
10.1038/eye.2000.137
10.1016/j.exer.2011.12.017
10.1016/S0161-6420(84)34248-8
10.1016/0002-9394(89)90805-2
10.1167/iovs.11-7723
10.1076/0271-3683(200005)2051-1FT347
10.3109/02713689109020340
10.1167/iovs.14-14872
10.1016/j.exer.2005.10.006
10.1089/jop.2013.0175
10.1186/1471-213X-1-3
10.1007/BF00406980
10.1016/j.exer.2009.02.007
10.1016/S0161-6420(84)34241-5
10.1167/iovs.05-0101
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Keywords Glaucoma
Conventional outflow
Fibroblast growth factor
Phosphate-buffered saline
Interleukin
Ocular hypertension
Matrix gla protein
Fetal bovine serum
Dulbecco's modified Eagle's medium
Ethylenediaminetetraacetic acid
Juxtacanalicular tissue
Trabecular meshwork
Aqueous humor dynamics
Tumor necrosis factor
Schlemm's canal
Dimethyl sulfoxide
Institutional review board
Human immunodeficiency virus
Intraocular pressure
Language English
License Copyright © 2018. Published by Elsevier Ltd.
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References Stamer, Roberts, Howell, Epstein (bib52) 1998; 39
Stamer, Seftor, Williams, Samaha, Snyder (bib53) 1995; 14
Grant, Tran, Bhattacharya, Bianchi (bib23) 2013; 246
Alvarado, Murphy, Juster (bib2) 1984; 91
Ge, Navarro, Kessler, Bernier, Perl, Sarno, Masferrer, Hannig, Stamer (bib19) 2016; 57
Siegner, May, Welge-Lussen, Bloemendal, Lutjen-Drecoll (bib47) 1996; 71
Braunger, Ademoglu, Koschade, Fuchshofer, Gabelt, Kiland, Hennes-Beann, Brunner, Kaufman, Tamm (bib8) 2014; 55
Tamm, Russell, Piatigorsky (bib58) 1999; 40
Gong, Tripathi, Tripathi (bib20) 1996; 33
Perkumas, Stamer (bib38) 2012; 96
Resch, Hann, Cook, Fautsch (bib43) 2010; 91
Mao, Liu, Wordinger, Clark (bib32) 2013; 54
Freddo (bib17) 2013; 32
Lutjen-Drecoll (bib31) 1999; 18
Stamer, Roberts, Epstein, Allingham (bib50) 2000; 20
Bermudez, Webber, Brown, Braun, Clark, Mao (bib6) 2017; 12
Hernandez, Weinstein, Schwartz, Ritch, Gordon, Southren (bib25) 1987; 28
Fautsch, Bahler, Jewison, Johnson (bib13) 2000; 41
Flugel, Tamm, Lutjen-Drecoll (bib16) 1991; 52
Clark, Miggans, Wilson, Browder, McCartney (bib9) 1995; 4
Du, Roh, Mann, Funderburgh, Funderburgh, Schuman (bib12) 2012; 53
Sherwood, Reina-Torres, Bertrand, Rowe, Overby (bib46) 2016; 11
Fuchshofer, Welge-Lussen, Lutjen-Drecoll, Birke (bib18) 2006; 47
Tamm (bib55) 2009; 88
Jacobson, Andrews, Shepard, Nishimura, Searby, Fingert, Hageman, Mullins, Davidson, Kwon, Alward, Stone, Clark, Sheffield (bib27) 2001; 10
Coroneo, Korbmacher, Flugel, Stiemer, Lutjen-Drecoll, Wiederholt (bib10) 1991; 52
McMenamin, Steptoe (bib34) 1991; 178
Morgan, Raghunathan, Chang, Murphy, Russell (bib35) 2015; 6
Xue, Comes, Borras (bib65) 2007; 48
Filla, Liu, Nguyen, Polansky, Brandt, Kaufman, Peters (bib15) 2002; 43
Morgan, Wood, Walker, Raghunathan, Borjesson, Murphy, Russell (bib36) 2014; 30
Bradley, Kelley, Rose, Acott (bib7) 2003; 44
Fautsch, Howell, Vrabel, Charlesworth, Muddiman, Johnson (bib14) 2005; 46
Tamm, Kellenberger (bib56) 2008
Acott, Samples, Bradley, Bacon, Bylsma, Van Buskirk (bib1) 1989; 107
Anderssohn, Cox, O'Malley, Dees, Hosseini, Boren, Wagner, Bradley, Kelley, Acott (bib4) 2011; 52
Polansky, Wood, Maglio, Alvarado (bib42) 1984; 91
Whikehart, Parikh, Vaughn, Mishler, Edelhauser (bib63) 2005; 11
Gonzalez, Epstein, Luna, Liton (bib21) 2006; 82
Polansky, Weinreb, Alvarado (bib40) 1981; 21
Smith, Zabaleta, Savinova, John (bib48) 2001; 1
Begley, Yue, Hendricks (bib5) 1991; 10
Lin, Lee, Minasi, Wong (bib30) 2007; 32
Alvarado, Murphy, Polansky, Juster (bib3) 1981; 21
Kelley, Rose, Keller, Hessle, Samples, Acott (bib29) 2009; 88
Tamm, Russell, Johnson, Piatigorsky (bib57) 1996; 37
Keller, Acott (bib28) 2013; 1
Polansky, Fauss, Zimmerman (bib39) 2000; 14
Steely, Browder, Julian, Miggans, Wilson, Clark (bib54) 1992; 33
Hosaka, Rodriguez-Vazquez, Abe, Murakami, Fujimiya, Ohguro (bib26) 2013; 46
Rhee, Tamm, Russell (bib44) 2003; 77
Rohen, Schachtschabel, Matthiessen (bib45) 1975; 193
Welge-Lussen, May, Eichhorn, Bloemendal, Lutjen-Drecoll (bib62) 1999; 40
Taniguchi, Suzuki, Kurihara, Kurihara, Kasai, Shirato, Araie (bib60) 2000; 41
Danias, Gerometta, Ge, Ren, Panagis, Mittag, Candia, Podos (bib11) 2011; 52
Wirtz, Samples, Xu, Severson, Acott (bib64) 2002; 43
Gospodarowicz, Ill (bib22) 1980; 65
Stamer, Clark (bib51) 2017; 158
Polansky, Weinreb, Baxter, Alvarado (bib41) 1979; 18
Pang, Shade, Clark, Steely, DeSantis (bib37) 1994; 13
Grierson, Lee, Abraham, Howes (bib24) 1978; 208
Snider, Vannatta, Schildmeyer, Stamer, Ethier (bib49) 2017
Tripathi, Tripathi (bib61) 1982; 35
Mao, Liu, Wordinger, Clark (bib33) 2013; 54
Tamm, Russell, Piatigorsky (bib59) 1999; 40
Tamm (10.1016/j.exer.2018.03.001_bib55) 2009; 88
Tamm (10.1016/j.exer.2018.03.001_bib58) 1999; 40
Polansky (10.1016/j.exer.2018.03.001_bib41) 1979; 18
Hosaka (10.1016/j.exer.2018.03.001_bib26) 2013; 46
Alvarado (10.1016/j.exer.2018.03.001_bib2) 1984; 91
Fautsch (10.1016/j.exer.2018.03.001_bib14) 2005; 46
Tripathi (10.1016/j.exer.2018.03.001_bib61) 1982; 35
Whikehart (10.1016/j.exer.2018.03.001_bib63) 2005; 11
Polansky (10.1016/j.exer.2018.03.001_bib42) 1984; 91
Ge (10.1016/j.exer.2018.03.001_bib19) 2016; 57
Polansky (10.1016/j.exer.2018.03.001_bib39) 2000; 14
Tamm (10.1016/j.exer.2018.03.001_bib56) 2008
Welge-Lussen (10.1016/j.exer.2018.03.001_bib62) 1999; 40
Siegner (10.1016/j.exer.2018.03.001_bib47) 1996; 71
Stamer (10.1016/j.exer.2018.03.001_bib52) 1998; 39
Stamer (10.1016/j.exer.2018.03.001_bib50) 2000; 20
Mao (10.1016/j.exer.2018.03.001_bib32) 2013; 54
Smith (10.1016/j.exer.2018.03.001_bib48) 2001; 1
Bradley (10.1016/j.exer.2018.03.001_bib7) 2003; 44
Coroneo (10.1016/j.exer.2018.03.001_bib10) 1991; 52
Gong (10.1016/j.exer.2018.03.001_bib20) 1996; 33
Danias (10.1016/j.exer.2018.03.001_bib11) 2011; 52
Gonzalez (10.1016/j.exer.2018.03.001_bib21) 2006; 82
Xue (10.1016/j.exer.2018.03.001_bib65) 2007; 48
Wirtz (10.1016/j.exer.2018.03.001_bib64) 2002; 43
Fautsch (10.1016/j.exer.2018.03.001_bib13) 2000; 41
Keller (10.1016/j.exer.2018.03.001_bib28) 2013; 1
Perkumas (10.1016/j.exer.2018.03.001_bib38) 2012; 96
Freddo (10.1016/j.exer.2018.03.001_bib17) 2013; 32
Rhee (10.1016/j.exer.2018.03.001_bib44) 2003; 77
Rohen (10.1016/j.exer.2018.03.001_bib45) 1975; 193
Bermudez (10.1016/j.exer.2018.03.001_bib6) 2017; 12
Gospodarowicz (10.1016/j.exer.2018.03.001_bib22) 1980; 65
Stamer (10.1016/j.exer.2018.03.001_bib51) 2017; 158
Flugel (10.1016/j.exer.2018.03.001_bib16) 1991; 52
Resch (10.1016/j.exer.2018.03.001_bib43) 2010; 91
Clark (10.1016/j.exer.2018.03.001_bib9) 1995; 4
Steely (10.1016/j.exer.2018.03.001_bib54) 1992; 33
Grant (10.1016/j.exer.2018.03.001_bib23) 2013; 246
Lutjen-Drecoll (10.1016/j.exer.2018.03.001_bib31) 1999; 18
Stamer (10.1016/j.exer.2018.03.001_bib53) 1995; 14
Morgan (10.1016/j.exer.2018.03.001_bib35) 2015; 6
Snider (10.1016/j.exer.2018.03.001_bib49) 2017
Morgan (10.1016/j.exer.2018.03.001_bib36) 2014; 30
Pang (10.1016/j.exer.2018.03.001_bib37) 1994; 13
Du (10.1016/j.exer.2018.03.001_bib12) 2012; 53
Hernandez (10.1016/j.exer.2018.03.001_bib25) 1987; 28
Anderssohn (10.1016/j.exer.2018.03.001_bib4) 2011; 52
Kelley (10.1016/j.exer.2018.03.001_bib29) 2009; 88
Braunger (10.1016/j.exer.2018.03.001_bib8) 2014; 55
Fuchshofer (10.1016/j.exer.2018.03.001_bib18) 2006; 47
Filla (10.1016/j.exer.2018.03.001_bib15) 2002; 43
Acott (10.1016/j.exer.2018.03.001_bib1) 1989; 107
Lin (10.1016/j.exer.2018.03.001_bib30) 2007; 32
Tamm (10.1016/j.exer.2018.03.001_bib59) 1999; 40
Polansky (10.1016/j.exer.2018.03.001_bib40) 1981; 21
Begley (10.1016/j.exer.2018.03.001_bib5) 1991; 10
Taniguchi (10.1016/j.exer.2018.03.001_bib60) 2000; 41
Alvarado (10.1016/j.exer.2018.03.001_bib3) 1981; 21
McMenamin (10.1016/j.exer.2018.03.001_bib34) 1991; 178
Grierson (10.1016/j.exer.2018.03.001_bib24) 1978; 208
Sherwood (10.1016/j.exer.2018.03.001_bib46) 2016; 11
Jacobson (10.1016/j.exer.2018.03.001_bib27) 2001; 10
Tamm (10.1016/j.exer.2018.03.001_bib57) 1996; 37
Mao (10.1016/j.exer.2018.03.001_bib33) 2013; 54
References_xml – volume: 43
  start-page: 151
  year: 2002
  end-page: 161
  ident: bib15
  article-title: In vitro localization of TIGR/MYOC in trabecular meshwork extracellular matrix and binding to fibronectin
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 6
  start-page: 15362
  year: 2015
  end-page: 15374
  ident: bib35
  article-title: The intrinsic stiffness of human trabecular meshwork cells increases with senescence
  publication-title: Oncotarget
– volume: 32
  start-page: 181
  year: 2013
  end-page: 195
  ident: bib17
  article-title: A contemporary concept of the blood-aqueous barrier
  publication-title: Prog. Retin. Eye Res.
– volume: 35
  start-page: 611
  year: 1982
  end-page: 624
  ident: bib61
  article-title: Human trabecular endothelium, corneal endothelium, keratocytes, and scleral fibroblasts in primary cell culture. A comparative study of growth characteristics, morphology, and phagocytic activity by light and scanning electron microscopy
  publication-title: Exp. Eye Res.
– volume: 40
  start-page: 2235
  year: 1999
  end-page: 2241
  ident: bib62
  article-title: AlphaB-crystallin in the trabecular meshwork is inducible by transforming growth factor-beta
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 52
  start-page: 681
  year: 1991
  end-page: 690
  ident: bib16
  article-title: Different cell populations in bovine trabecular meshwork: an ultrastructural and immunocytochemical study
  publication-title: Exp. Eye Res.
– volume: 41
  start-page: 2070
  year: 2000
  end-page: 2075
  ident: bib60
  article-title: Molecular cloning of the bovine MYOC and induction of its expression in trabecular meshwork cells
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 43
  start-page: 3698
  year: 2002
  end-page: 3704
  ident: bib64
  article-title: Expression profile and genome location of cDNA clones from an infant human trabecular meshwork cell library
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 82
  start-page: 959
  year: 2006
  end-page: 967
  ident: bib21
  article-title: Characterization of free-floating spheres from human trabecular meshwork (HTM) cell culture in vitro
  publication-title: Exp. Eye Res.
– volume: 57
  start-page: 1317
  year: 2016
  end-page: 1326
  ident: bib19
  article-title: The soluble guanylate cyclase stimulator IWP-953 increases conventional outflow facility in mouse eyes
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 91
  start-page: 564
  year: 1984
  end-page: 579
  ident: bib2
  article-title: Trabecular meshwork cellularity in primary open-angle glaucoma and nonglaucomatous normals
  publication-title: Ophthalmology
– volume: 47
  start-page: 794
  year: 2006
  end-page: 801
  ident: bib18
  article-title: Biochemical and morphological analysis of basement membrane component expression in corneoscleral and cribriform human trabecular meshwork cells
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 54
  start-page: 3600
  year: 2013
  end-page: 3606
  ident: bib32
  article-title: A magnetic bead-based method for mouse trabecular meshwork cell isolation
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 71
  start-page: 165
  year: 1996
  end-page: 169
  ident: bib47
  article-title: Alpha B-crystallin in the primate ciliary muscle and trabecular meshwork
  publication-title: Eur. J. Cell Biol.
– volume: 11
  start-page: 816
  year: 2005
  end-page: 824
  ident: bib63
  article-title: Evidence suggesting the existence of stem cells for the human corneal endothelium
  publication-title: Mol. Vis.
– volume: 33
  start-page: 2242
  year: 1992
  end-page: 2250
  ident: bib54
  article-title: The effects of dexamethasone on fibronectin expression in cultured human trabecular meshwork cells
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 91
  start-page: 901
  year: 2010
  end-page: 908
  ident: bib43
  article-title: Aqueous humor rapidly stimulates myocilin secretion from human trabecular meshwork cells
  publication-title: Exp. Eye Res.
– volume: 46
  start-page: 2848
  year: 2005
  end-page: 2856
  ident: bib14
  article-title: Primary trabecular meshwork cells incubated in human aqueous humor differ from cells incubated in serum supplements
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 65
  start-page: 1351
  year: 1980
  end-page: 1364
  ident: bib22
  article-title: Extracellular matrix and control of proliferation of vascular endothelial cells
  publication-title: J. Clin. Invest.
– year: 2017
  ident: bib49
  article-title: Characterizing differences between MSCs and TM cells: toward autologous stem cell therapies for the glaucomatous trabecular meshwork
  publication-title: J Tissue Eng Regen Med
– volume: 52
  start-page: 7548
  year: 2011
  end-page: 7555
  ident: bib4
  article-title: Molecular chaperone function for myocilin
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 14
  start-page: 503
  year: 2000
  end-page: 514
  ident: bib39
  article-title: Regulation of TIGR/MYOC gene expression in human trabecular meshwork cells
  publication-title: Eye (Lond)
– volume: 77
  start-page: 749
  year: 2003
  end-page: 756
  ident: bib44
  article-title: Donor corneoscleral buttons: a new source of trabecular meshwork for research
  publication-title: Exp. Eye Res.
– volume: 88
  start-page: 648
  year: 2009
  end-page: 655
  ident: bib55
  article-title: The trabecular meshwork outflow pathways: structural and functional aspects
  publication-title: Exp. Eye Res.
– volume: 54
  start-page: 3600
  year: 2013
  end-page: 3606
  ident: bib33
  article-title: A magnetic bead-based method for mouse trabecular meshwork cell isolation
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 1
  start-page: 3
  year: 2001
  ident: bib48
  article-title: The mouse anterior chamber angle and trabecular meshwork develop without cell death
  publication-title: BMC Dev. Biol.
– volume: 48
  start-page: 3184
  year: 2007
  end-page: 3194
  ident: bib65
  article-title: Presence of an established calcification marker in trabecular meshwork tissue of glaucoma donors
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 246
  start-page: 167
  year: 2013
  end-page: 175
  ident: bib23
  article-title: Ionic currents of human trabecular meshwork cells from control and glaucoma subjects
  publication-title: J. Membr. Biol.
– volume: 18
  start-page: 91
  year: 1999
  end-page: 119
  ident: bib31
  article-title: Functional morphology of the trabecular meshwork in primate eyes
  publication-title: Prog. Retin. Eye Res.
– volume: 20
  start-page: 347
  year: 2000
  end-page: 350
  ident: bib50
  article-title: Isolation of primary open-angle glaucomatous trabecular meshwork cells from whole eye tissue
  publication-title: Curr. Eye Res.
– volume: 96
  start-page: 82
  year: 2012
  end-page: 87
  ident: bib38
  article-title: Protein markers and differentiation in culture for Schlemm's canal endothelial cells
  publication-title: Exp. Eye Res.
– volume: 158
  start-page: 112
  year: 2017
  end-page: 123
  ident: bib51
  article-title: The many faces of the trabecular meshwork cell
  publication-title: Exp. Eye Res.
– volume: 107
  start-page: 1
  year: 1989
  end-page: 6
  ident: bib1
  article-title: Trabecular repopulation by anterior trabecular meshwork cells after laser trabeculoplasty
  publication-title: Am. J. Ophthalmol.
– volume: 4
  start-page: 183
  year: 1995
  end-page: 188
  ident: bib9
  article-title: Cytoskeletal changes in cultured human glaucoma trabecular meshwork cells
  publication-title: J. Glaucoma
– volume: 40
  start-page: 1392
  year: 1999
  end-page: 1403
  ident: bib59
  article-title: Development of characterization of a immortal and differentiated murine trabecular meshwork cell line
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 28
  start-page: 1655
  year: 1987
  end-page: 1660
  ident: bib25
  article-title: Human trabecular meshwork cells in culture: morphology and extracellular matrix components
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 46
  start-page: 49
  year: 2013
  end-page: 56
  ident: bib26
  article-title: Qualitative changes in fetal trabecular meshwork fibers at the human iridocorneal angle
  publication-title: Anat Cell Biol
– volume: 10
  start-page: 1015
  year: 1991
  end-page: 1030
  ident: bib5
  article-title: Murine trabecular meshwork cells in tissue culture
  publication-title: Curr. Eye Res.
– volume: 44
  start-page: 5174
  year: 2003
  end-page: 5181
  ident: bib7
  article-title: Signaling pathways used in trabecular matrix metalloproteinase response to mechanical stretch
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 52
  start-page: 8636
  year: 2011
  end-page: 8645
  ident: bib11
  article-title: Gene expression changes in steroid-induced IOP elevation in bovine trabecular meshwork
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 208
  start-page: 33
  year: 1978
  end-page: 47
  ident: bib24
  article-title: Associations between the cells of the walls of Schlemm's canal
  publication-title: Albrecht Von Graefes Arch. Klin. Exp. Ophthalmol.
– volume: 88
  start-page: 747
  year: 2009
  end-page: 751
  ident: bib29
  article-title: Stem cells in the trabecular meshwork: present and future promises
  publication-title: Exp. Eye Res.
– volume: 53
  start-page: 1566
  year: 2012
  end-page: 1575
  ident: bib12
  article-title: Multipotent stem cells from trabecular meshwork become phagocytic TM cells
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 193
  start-page: 95
  year: 1975
  end-page: 107
  ident: bib45
  article-title: In vitro studies on the trabecular meshwork of the primate eye
  publication-title: Albrecht Von Graefes Arch. Klin. Exp. Ophthalmol.
– volume: 21
  start-page: 155
  year: 1981
  end-page: 160
  ident: bib40
  article-title: Studies on human trabecular cells propagated in vitro
  publication-title: Vis. Res.
– volume: 52
  start-page: 375
  year: 1991
  end-page: 388
  ident: bib10
  article-title: Electrical and morphological evidence for heterogeneous populations of cultured bovine trabecular meshwork cells
  publication-title: Exp. Eye Res.
– volume: 37
  start-page: 2402
  year: 1996
  end-page: 2413
  ident: bib57
  article-title: Human and monkey trabecular meshwork accumulate alpha B-crystallin in response to heat shock and oxidative stress
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 40
  start-page: 1392
  year: 1999
  end-page: 1403
  ident: bib58
  article-title: Development and characterization of an immortal and differentiated murine trabecular meshwork cell line
  publication-title: Invest. Ophthalmol. Vis. Sci.
– start-page: 129
  year: 2008
  end-page: 134
  ident: bib56
  article-title: Aqueous humor dynamics and trabecular meshwork
  publication-title: Eye, Retina, and Visual System of the Mouse
– volume: 33
  start-page: 336
  year: 1996
  end-page: 367
  ident: bib20
  article-title: Morphology of the aqueous outflow pathway
  publication-title: Microsc. Res. Tech.
– volume: 10
  start-page: 117
  year: 2001
  end-page: 125
  ident: bib27
  article-title: Non-secretion of mutant proteins of the glaucoma gene myocilin in cultured trabecular meshwork cells and in aqueous humor
  publication-title: Hum. Mol. Genet.
– volume: 91
  start-page: 580
  year: 1984
  end-page: 595
  ident: bib42
  article-title: Trabecular meshwork cell culture in glaucoma research: evaluation of biological activity and structural properties of human trabecular cells in vitro
  publication-title: Ophthalmology
– volume: 14
  start-page: 611
  year: 1995
  end-page: 617
  ident: bib53
  article-title: Isolation and culture of human trabecular meshwork cells by extracellular matrix digestion
  publication-title: Curr. Eye Res.
– volume: 13
  start-page: 51
  year: 1994
  end-page: 63
  ident: bib37
  article-title: Preliminary characterization of a transformed cell strain derived from human trabecular meshwork
  publication-title: Curr. Eye Res.
– volume: 178
  start-page: 65
  year: 1991
  end-page: 77
  ident: bib34
  article-title: Normal anatomy of the aqueous humour outflow system in the domestic pig eye
  publication-title: J. Anat.
– volume: 30
  start-page: 254
  year: 2014
  end-page: 266
  ident: bib36
  article-title: Human trabecular meshwork cells exhibit several characteristics of, but are distinct from, adipose-derived mesenchymal stem cells
  publication-title: J. Ocul. Pharmacol. Therapeut.
– volume: 11
  start-page: e0150694
  year: 2016
  ident: bib46
  article-title: Measurement of outflow facility using iPerfusion
  publication-title: PLoS One
– volume: 12
  start-page: e0169671
  year: 2017
  ident: bib6
  article-title: A comparison of gene expression profiles between glucocorticoid responder and non-responder bovine trabecular meshwork cells using RNA sequencing
  publication-title: PLoS One
– volume: 18
  start-page: 1043
  year: 1979
  end-page: 1049
  ident: bib41
  article-title: Human trabecular cells. I. Establishment in tissue culture and growth characteristics
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 55
  start-page: 7499
  year: 2014
  end-page: 7507
  ident: bib8
  article-title: Identification of adult stem cells in Schwalbe's line region of the primate eye
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 32
  start-page: 43
  year: 2007
  end-page: 50
  ident: bib30
  article-title: Isolation, culture, and characterization of human fetal trabecular meshwork cells
  publication-title: Curr. Eye Res.
– volume: 21
  start-page: 714
  year: 1981
  end-page: 727
  ident: bib3
  article-title: Age-related changes in trabecular meshwork cellularity
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 41
  start-page: 4163
  year: 2000
  end-page: 4168
  ident: bib13
  article-title: Recombinant TIGR/MYOC increases outflow resistance in the human anterior segment
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 39
  start-page: 1804
  year: 1998
  end-page: 1812
  ident: bib52
  article-title: Isolation, culture, and characterization of endothelial cells from Schlemm's canal
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 1
  start-page: 3
  year: 2013
  ident: bib28
  article-title: The juxtacanalicular region of ocular trabecular meshwork: a tissue with a unique extracellular matrix and specialized function
  publication-title: J. Ocul. Biol.
– volume: 54
  start-page: 3600
  year: 2013
  ident: 10.1016/j.exer.2018.03.001_bib33
  article-title: A magnetic bead-based method for mouse trabecular meshwork cell isolation
  publication-title: Invest. Ophthalmol. Vis. Sci.
  doi: 10.1167/iovs.13-12033
– volume: 21
  start-page: 155
  year: 1981
  ident: 10.1016/j.exer.2018.03.001_bib40
  article-title: Studies on human trabecular cells propagated in vitro
  publication-title: Vis. Res.
  doi: 10.1016/0042-6989(81)90151-6
– volume: 33
  start-page: 336
  year: 1996
  ident: 10.1016/j.exer.2018.03.001_bib20
  article-title: Morphology of the aqueous outflow pathway
  publication-title: Microsc. Res. Tech.
  doi: 10.1002/(SICI)1097-0029(19960301)33:4<336::AID-JEMT4>3.0.CO;2-N
– volume: 28
  start-page: 1655
  year: 1987
  ident: 10.1016/j.exer.2018.03.001_bib25
  article-title: Human trabecular meshwork cells in culture: morphology and extracellular matrix components
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 91
  start-page: 901
  year: 2010
  ident: 10.1016/j.exer.2018.03.001_bib43
  article-title: Aqueous humor rapidly stimulates myocilin secretion from human trabecular meshwork cells
  publication-title: Exp. Eye Res.
  doi: 10.1016/j.exer.2010.09.017
– volume: 18
  start-page: 1043
  year: 1979
  ident: 10.1016/j.exer.2018.03.001_bib41
  article-title: Human trabecular cells. I. Establishment in tissue culture and growth characteristics
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 193
  start-page: 95
  year: 1975
  ident: 10.1016/j.exer.2018.03.001_bib45
  article-title: In vitro studies on the trabecular meshwork of the primate eye
  publication-title: Albrecht Von Graefes Arch. Klin. Exp. Ophthalmol.
  doi: 10.1007/BF00419354
– volume: 11
  start-page: e0150694
  year: 2016
  ident: 10.1016/j.exer.2018.03.001_bib46
  article-title: Measurement of outflow facility using iPerfusion
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0150694
– volume: 6
  start-page: 15362
  year: 2015
  ident: 10.1016/j.exer.2018.03.001_bib35
  article-title: The intrinsic stiffness of human trabecular meshwork cells increases with senescence
  publication-title: Oncotarget
  doi: 10.18632/oncotarget.3798
– volume: 35
  start-page: 611
  year: 1982
  ident: 10.1016/j.exer.2018.03.001_bib61
  article-title: Human trabecular endothelium, corneal endothelium, keratocytes, and scleral fibroblasts in primary cell culture. A comparative study of growth characteristics, morphology, and phagocytic activity by light and scanning electron microscopy
  publication-title: Exp. Eye Res.
  doi: 10.1016/S0014-4835(82)80074-2
– volume: 40
  start-page: 1392
  year: 1999
  ident: 10.1016/j.exer.2018.03.001_bib59
  article-title: Development of characterization of a immortal and differentiated murine trabecular meshwork cell line
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 1
  start-page: 3
  year: 2013
  ident: 10.1016/j.exer.2018.03.001_bib28
  article-title: The juxtacanalicular region of ocular trabecular meshwork: a tissue with a unique extracellular matrix and specialized function
  publication-title: J. Ocul. Biol.
– start-page: 129
  year: 2008
  ident: 10.1016/j.exer.2018.03.001_bib56
  article-title: Aqueous humor dynamics and trabecular meshwork
– volume: 37
  start-page: 2402
  year: 1996
  ident: 10.1016/j.exer.2018.03.001_bib57
  article-title: Human and monkey trabecular meshwork accumulate alpha B-crystallin in response to heat shock and oxidative stress
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 39
  start-page: 1804
  year: 1998
  ident: 10.1016/j.exer.2018.03.001_bib52
  article-title: Isolation, culture, and characterization of endothelial cells from Schlemm's canal
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 43
  start-page: 3698
  year: 2002
  ident: 10.1016/j.exer.2018.03.001_bib64
  article-title: Expression profile and genome location of cDNA clones from an infant human trabecular meshwork cell library
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 52
  start-page: 8636
  year: 2011
  ident: 10.1016/j.exer.2018.03.001_bib11
  article-title: Gene expression changes in steroid-induced IOP elevation in bovine trabecular meshwork
  publication-title: Invest. Ophthalmol. Vis. Sci.
  doi: 10.1167/iovs.11-7563
– volume: 32
  start-page: 181
  year: 2013
  ident: 10.1016/j.exer.2018.03.001_bib17
  article-title: A contemporary concept of the blood-aqueous barrier
  publication-title: Prog. Retin. Eye Res.
  doi: 10.1016/j.preteyeres.2012.10.004
– volume: 57
  start-page: 1317
  year: 2016
  ident: 10.1016/j.exer.2018.03.001_bib19
  article-title: The soluble guanylate cyclase stimulator IWP-953 increases conventional outflow facility in mouse eyes
  publication-title: Invest. Ophthalmol. Vis. Sci.
  doi: 10.1167/iovs.15-18958
– volume: 43
  start-page: 151
  year: 2002
  ident: 10.1016/j.exer.2018.03.001_bib15
  article-title: In vitro localization of TIGR/MYOC in trabecular meshwork extracellular matrix and binding to fibronectin
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 10
  start-page: 117
  year: 2001
  ident: 10.1016/j.exer.2018.03.001_bib27
  article-title: Non-secretion of mutant proteins of the glaucoma gene myocilin in cultured trabecular meshwork cells and in aqueous humor
  publication-title: Hum. Mol. Genet.
  doi: 10.1093/hmg/10.2.117
– volume: 40
  start-page: 1392
  year: 1999
  ident: 10.1016/j.exer.2018.03.001_bib58
  article-title: Development and characterization of an immortal and differentiated murine trabecular meshwork cell line
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 246
  start-page: 167
  year: 2013
  ident: 10.1016/j.exer.2018.03.001_bib23
  article-title: Ionic currents of human trabecular meshwork cells from control and glaucoma subjects
  publication-title: J. Membr. Biol.
  doi: 10.1007/s00232-012-9517-4
– volume: 52
  start-page: 681
  year: 1991
  ident: 10.1016/j.exer.2018.03.001_bib16
  article-title: Different cell populations in bovine trabecular meshwork: an ultrastructural and immunocytochemical study
  publication-title: Exp. Eye Res.
  doi: 10.1016/0014-4835(91)90020-F
– volume: 77
  start-page: 749
  year: 2003
  ident: 10.1016/j.exer.2018.03.001_bib44
  article-title: Donor corneoscleral buttons: a new source of trabecular meshwork for research
  publication-title: Exp. Eye Res.
  doi: 10.1016/j.exer.2003.07.008
– volume: 52
  start-page: 375
  year: 1991
  ident: 10.1016/j.exer.2018.03.001_bib10
  article-title: Electrical and morphological evidence for heterogeneous populations of cultured bovine trabecular meshwork cells
  publication-title: Exp. Eye Res.
  doi: 10.1016/0014-4835(91)90032-A
– volume: 65
  start-page: 1351
  year: 1980
  ident: 10.1016/j.exer.2018.03.001_bib22
  article-title: Extracellular matrix and control of proliferation of vascular endothelial cells
  publication-title: J. Clin. Invest.
  doi: 10.1172/JCI109799
– volume: 48
  start-page: 3184
  year: 2007
  ident: 10.1016/j.exer.2018.03.001_bib65
  article-title: Presence of an established calcification marker in trabecular meshwork tissue of glaucoma donors
  publication-title: Invest. Ophthalmol. Vis. Sci.
  doi: 10.1167/iovs.06-1403
– volume: 40
  start-page: 2235
  year: 1999
  ident: 10.1016/j.exer.2018.03.001_bib62
  article-title: AlphaB-crystallin in the trabecular meshwork is inducible by transforming growth factor-beta
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 71
  start-page: 165
  year: 1996
  ident: 10.1016/j.exer.2018.03.001_bib47
  article-title: Alpha B-crystallin in the primate ciliary muscle and trabecular meshwork
  publication-title: Eur. J. Cell Biol.
– volume: 47
  start-page: 794
  year: 2006
  ident: 10.1016/j.exer.2018.03.001_bib18
  article-title: Biochemical and morphological analysis of basement membrane component expression in corneoscleral and cribriform human trabecular meshwork cells
  publication-title: Invest. Ophthalmol. Vis. Sci.
  doi: 10.1167/iovs.05-0292
– volume: 46
  start-page: 49
  year: 2013
  ident: 10.1016/j.exer.2018.03.001_bib26
  article-title: Qualitative changes in fetal trabecular meshwork fibers at the human iridocorneal angle
  publication-title: Anat Cell Biol
  doi: 10.5115/acb.2013.46.1.49
– volume: 53
  start-page: 1566
  year: 2012
  ident: 10.1016/j.exer.2018.03.001_bib12
  article-title: Multipotent stem cells from trabecular meshwork become phagocytic TM cells
  publication-title: Invest. Ophthalmol. Vis. Sci.
  doi: 10.1167/iovs.11-9134
– volume: 14
  start-page: 611
  year: 1995
  ident: 10.1016/j.exer.2018.03.001_bib53
  article-title: Isolation and culture of human trabecular meshwork cells by extracellular matrix digestion
  publication-title: Curr. Eye Res.
  doi: 10.3109/02713689508998409
– volume: 12
  start-page: e0169671
  year: 2017
  ident: 10.1016/j.exer.2018.03.001_bib6
  article-title: A comparison of gene expression profiles between glucocorticoid responder and non-responder bovine trabecular meshwork cells using RNA sequencing
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0169671
– year: 2017
  ident: 10.1016/j.exer.2018.03.001_bib49
  article-title: Characterizing differences between MSCs and TM cells: toward autologous stem cell therapies for the glaucomatous trabecular meshwork
  publication-title: J Tissue Eng Regen Med
– volume: 44
  start-page: 5174
  year: 2003
  ident: 10.1016/j.exer.2018.03.001_bib7
  article-title: Signaling pathways used in trabecular matrix metalloproteinase response to mechanical stretch
  publication-title: Invest. Ophthalmol. Vis. Sci.
  doi: 10.1167/iovs.03-0213
– volume: 18
  start-page: 91
  year: 1999
  ident: 10.1016/j.exer.2018.03.001_bib31
  article-title: Functional morphology of the trabecular meshwork in primate eyes
  publication-title: Prog. Retin. Eye Res.
  doi: 10.1016/S1350-9462(98)00011-1
– volume: 4
  start-page: 183
  year: 1995
  ident: 10.1016/j.exer.2018.03.001_bib9
  article-title: Cytoskeletal changes in cultured human glaucoma trabecular meshwork cells
  publication-title: J. Glaucoma
  doi: 10.1097/00061198-199506000-00007
– volume: 32
  start-page: 43
  year: 2007
  ident: 10.1016/j.exer.2018.03.001_bib30
  article-title: Isolation, culture, and characterization of human fetal trabecular meshwork cells
  publication-title: Curr. Eye Res.
  doi: 10.1080/02713680601107058
– volume: 158
  start-page: 112
  year: 2017
  ident: 10.1016/j.exer.2018.03.001_bib51
  article-title: The many faces of the trabecular meshwork cell
  publication-title: Exp. Eye Res.
  doi: 10.1016/j.exer.2016.07.009
– volume: 88
  start-page: 747
  year: 2009
  ident: 10.1016/j.exer.2018.03.001_bib29
  article-title: Stem cells in the trabecular meshwork: present and future promises
  publication-title: Exp. Eye Res.
  doi: 10.1016/j.exer.2008.10.024
– volume: 41
  start-page: 2070
  year: 2000
  ident: 10.1016/j.exer.2018.03.001_bib60
  article-title: Molecular cloning of the bovine MYOC and induction of its expression in trabecular meshwork cells
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 54
  start-page: 3600
  year: 2013
  ident: 10.1016/j.exer.2018.03.001_bib32
  article-title: A magnetic bead-based method for mouse trabecular meshwork cell isolation
  publication-title: Invest. Ophthalmol. Vis. Sci.
  doi: 10.1167/iovs.13-12033
– volume: 13
  start-page: 51
  year: 1994
  ident: 10.1016/j.exer.2018.03.001_bib37
  article-title: Preliminary characterization of a transformed cell strain derived from human trabecular meshwork
  publication-title: Curr. Eye Res.
  doi: 10.3109/02713689409042398
– volume: 14
  start-page: 503
  issue: Pt 3B
  year: 2000
  ident: 10.1016/j.exer.2018.03.001_bib39
  article-title: Regulation of TIGR/MYOC gene expression in human trabecular meshwork cells
  publication-title: Eye (Lond)
  doi: 10.1038/eye.2000.137
– volume: 96
  start-page: 82
  year: 2012
  ident: 10.1016/j.exer.2018.03.001_bib38
  article-title: Protein markers and differentiation in culture for Schlemm's canal endothelial cells
  publication-title: Exp. Eye Res.
  doi: 10.1016/j.exer.2011.12.017
– volume: 91
  start-page: 564
  year: 1984
  ident: 10.1016/j.exer.2018.03.001_bib2
  article-title: Trabecular meshwork cellularity in primary open-angle glaucoma and nonglaucomatous normals
  publication-title: Ophthalmology
  doi: 10.1016/S0161-6420(84)34248-8
– volume: 107
  start-page: 1
  year: 1989
  ident: 10.1016/j.exer.2018.03.001_bib1
  article-title: Trabecular repopulation by anterior trabecular meshwork cells after laser trabeculoplasty
  publication-title: Am. J. Ophthalmol.
  doi: 10.1016/0002-9394(89)90805-2
– volume: 52
  start-page: 7548
  year: 2011
  ident: 10.1016/j.exer.2018.03.001_bib4
  article-title: Molecular chaperone function for myocilin
  publication-title: Invest. Ophthalmol. Vis. Sci.
  doi: 10.1167/iovs.11-7723
– volume: 178
  start-page: 65
  year: 1991
  ident: 10.1016/j.exer.2018.03.001_bib34
  article-title: Normal anatomy of the aqueous humour outflow system in the domestic pig eye
  publication-title: J. Anat.
– volume: 20
  start-page: 347
  year: 2000
  ident: 10.1016/j.exer.2018.03.001_bib50
  article-title: Isolation of primary open-angle glaucomatous trabecular meshwork cells from whole eye tissue
  publication-title: Curr. Eye Res.
  doi: 10.1076/0271-3683(200005)2051-1FT347
– volume: 33
  start-page: 2242
  year: 1992
  ident: 10.1016/j.exer.2018.03.001_bib54
  article-title: The effects of dexamethasone on fibronectin expression in cultured human trabecular meshwork cells
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 41
  start-page: 4163
  year: 2000
  ident: 10.1016/j.exer.2018.03.001_bib13
  article-title: Recombinant TIGR/MYOC increases outflow resistance in the human anterior segment
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 10
  start-page: 1015
  year: 1991
  ident: 10.1016/j.exer.2018.03.001_bib5
  article-title: Murine trabecular meshwork cells in tissue culture
  publication-title: Curr. Eye Res.
  doi: 10.3109/02713689109020340
– volume: 55
  start-page: 7499
  year: 2014
  ident: 10.1016/j.exer.2018.03.001_bib8
  article-title: Identification of adult stem cells in Schwalbe's line region of the primate eye
  publication-title: Invest. Ophthalmol. Vis. Sci.
  doi: 10.1167/iovs.14-14872
– volume: 82
  start-page: 959
  year: 2006
  ident: 10.1016/j.exer.2018.03.001_bib21
  article-title: Characterization of free-floating spheres from human trabecular meshwork (HTM) cell culture in vitro
  publication-title: Exp. Eye Res.
  doi: 10.1016/j.exer.2005.10.006
– volume: 30
  start-page: 254
  year: 2014
  ident: 10.1016/j.exer.2018.03.001_bib36
  article-title: Human trabecular meshwork cells exhibit several characteristics of, but are distinct from, adipose-derived mesenchymal stem cells
  publication-title: J. Ocul. Pharmacol. Therapeut.
  doi: 10.1089/jop.2013.0175
– volume: 1
  start-page: 3
  year: 2001
  ident: 10.1016/j.exer.2018.03.001_bib48
  article-title: The mouse anterior chamber angle and trabecular meshwork develop without cell death
  publication-title: BMC Dev. Biol.
  doi: 10.1186/1471-213X-1-3
– volume: 11
  start-page: 816
  year: 2005
  ident: 10.1016/j.exer.2018.03.001_bib63
  article-title: Evidence suggesting the existence of stem cells for the human corneal endothelium
  publication-title: Mol. Vis.
– volume: 208
  start-page: 33
  year: 1978
  ident: 10.1016/j.exer.2018.03.001_bib24
  article-title: Associations between the cells of the walls of Schlemm's canal
  publication-title: Albrecht Von Graefes Arch. Klin. Exp. Ophthalmol.
  doi: 10.1007/BF00406980
– volume: 21
  start-page: 714
  year: 1981
  ident: 10.1016/j.exer.2018.03.001_bib3
  article-title: Age-related changes in trabecular meshwork cellularity
  publication-title: Invest. Ophthalmol. Vis. Sci.
– volume: 88
  start-page: 648
  year: 2009
  ident: 10.1016/j.exer.2018.03.001_bib55
  article-title: The trabecular meshwork outflow pathways: structural and functional aspects
  publication-title: Exp. Eye Res.
  doi: 10.1016/j.exer.2009.02.007
– volume: 91
  start-page: 580
  year: 1984
  ident: 10.1016/j.exer.2018.03.001_bib42
  article-title: Trabecular meshwork cell culture in glaucoma research: evaluation of biological activity and structural properties of human trabecular cells in vitro
  publication-title: Ophthalmology
  doi: 10.1016/S0161-6420(84)34241-5
– volume: 46
  start-page: 2848
  year: 2005
  ident: 10.1016/j.exer.2018.03.001_bib14
  article-title: Primary trabecular meshwork cells incubated in human aqueous humor differ from cells incubated in serum supplements
  publication-title: Invest. Ophthalmol. Vis. Sci.
  doi: 10.1167/iovs.05-0101
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Snippet Cultured trabecular meshwork (TM) cells are a valuable model system to study the cellular mechanisms involved in the regulation of conventional outflow...
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SubjectTerms Age Factors
Animals
Aqueous humor dynamics
Biomarkers - metabolism
Cell Culture Techniques
Cell Separation - methods
Consensus
Conventional outflow
Fetus
Glaucoma
Guidelines as Topic
Humans
Intraocular pressure
Ocular hypertension
Tissue and Organ Harvesting
Tissue Donors
Tissue Preservation
Trabecular Meshwork - cytology
Trabecular Meshwork - metabolism
Title Consensus recommendations for trabecular meshwork cell isolation, characterization and culture
URI https://dx.doi.org/10.1016/j.exer.2018.03.001
https://www.ncbi.nlm.nih.gov/pubmed/29526795
https://www.proquest.com/docview/2013103449
https://pubmed.ncbi.nlm.nih.gov/PMC6042513
Volume 171
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