The COVID-19 pandemic and physical activity
The SARS-CoV-2-caused COVID-19 pandemic has resulted in a devastating threat to human society in terms of health, economy, and lifestyle. Although the virus usually first invades and infects the lung and respiratory track tissue, in extreme cases, almost all major organs in the body are now known to...
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| Veröffentlicht in: | Sports medicine and health science Jg. 2; H. 2; S. 55 - 64 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , |
| Format: | Journal Article |
| Sprache: | Englisch |
| Veröffentlicht: |
Netherlands
Elsevier B.V
01.06.2020
Chengdu Sport University KeAi Communications Co., Ltd |
| Schlagworte: | |
| ISSN: | 2666-3376, 2666-3376 |
| Online-Zugang: | Volltext |
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| Abstract | The SARS-CoV-2-caused COVID-19 pandemic has resulted in a devastating threat to human society in terms of health, economy, and lifestyle. Although the virus usually first invades and infects the lung and respiratory track tissue, in extreme cases, almost all major organs in the body are now known to be negatively impacted often leading to severe systemic failure in some people. Unfortunately, there is currently no effective treatment for this disease. Pre-existing pathological conditions or comorbidities such as age are a major reason for premature death and increased morbidity and mortality. The immobilization due to hospitalization and bed rest and the physical inactivity due to sustained quarantine and social distancing can downregulate the ability of organs systems to resist to viral infection and increase the risk of damage to the immune, respiratory, cardiovascular, musculoskeletal systems and the brain. The cellular mechanisms and danger of this “second wave” effect of COVID-19 to the human body, along with the effects of aging, proper nutrition, and regular physical activity, are reviewed in this article. |
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| AbstractList | The SARS-CoV-2-caused COVID-19 pandemic has resulted in a devastating threat to human society in terms of health, economy, and lifestyle. Although the virus usually first invades and infects the lung and respiratory track tissue, in extreme cases, almost all major organs in the body are now known to be negatively impacted often leading to severe systemic failure in some people. Unfortunately, there is currently no effective treatment for this disease. Pre-existing pathological conditions or comorbidities such as age are a major reason for premature death and increased morbidity and mortality. The immobilization due to hospitalization and bed rest and the physical inactivity due to sustained quarantine and social distancing can downregulate the ability of organs systems to resist to viral infection and increase the risk of damage to the immune, respiratory, cardiovascular, musculoskeletal systems and the brain. The cellular mechanisms and danger of this "second wave" effect of COVID-19 to the human body, along with the effects of aging, proper nutrition, and regular physical activity, are reviewed in this article. The SARS-CoV-2-caused COVID-19 pandemic has resulted in a devastating threat to human society in terms of health, economy, and lifestyle. Although the virus usually first invades and infects the lung and respiratory track tissue, in extreme cases, almost all major organs in the body are now known to be negatively impacted often leading to severe systemic failure in some people. Unfortunately, there is currently no effective treatment for this disease. Pre-existing pathological conditions or comorbidities such as age are a major reason for premature death and increased morbidity and mortality. The immobilization due to hospitalization and bed rest and the physical inactivity due to sustained quarantine and social distancing can downregulate the ability of organs systems to resist to viral infection and increase the risk of damage to the immune, respiratory, cardiovascular, musculoskeletal systems and the brain. The cellular mechanisms and danger of this "second wave" effect of COVID-19 to the human body, along with the effects of aging, proper nutrition, and regular physical activity, are reviewed in this article.The SARS-CoV-2-caused COVID-19 pandemic has resulted in a devastating threat to human society in terms of health, economy, and lifestyle. Although the virus usually first invades and infects the lung and respiratory track tissue, in extreme cases, almost all major organs in the body are now known to be negatively impacted often leading to severe systemic failure in some people. Unfortunately, there is currently no effective treatment for this disease. Pre-existing pathological conditions or comorbidities such as age are a major reason for premature death and increased morbidity and mortality. The immobilization due to hospitalization and bed rest and the physical inactivity due to sustained quarantine and social distancing can downregulate the ability of organs systems to resist to viral infection and increase the risk of damage to the immune, respiratory, cardiovascular, musculoskeletal systems and the brain. The cellular mechanisms and danger of this "second wave" effect of COVID-19 to the human body, along with the effects of aging, proper nutrition, and regular physical activity, are reviewed in this article. |
| Author | Ji, Li Li Leeuwenburgh, Christiaan Cheng, Ying Coelho-Júnior, Hélio José Liu, Jiankang Gomez-Cabrera, Mari Carmen Radak, Zsolt Woods, Jeffrey A. Marzetti, Emanuele Powers, Scott K. Roberts, William O. Durstine, J. Larry Berkes, Istvan Hutchinson, Noah T. Boldogh, Istvan Sun, Junzhi Boros, Anita |
| Author_xml | – sequence: 1 givenname: Jeffrey A. surname: Woods fullname: Woods, Jeffrey A. organization: Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, USA – sequence: 2 givenname: Noah T. surname: Hutchinson fullname: Hutchinson, Noah T. organization: Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, USA – sequence: 3 givenname: Scott K. surname: Powers fullname: Powers, Scott K. organization: Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, USA – sequence: 4 givenname: William O. surname: Roberts fullname: Roberts, William O. organization: Department of Family Medicine and Community Health, University of Minnesota Medical School, Minneapolis, USA – sequence: 5 givenname: Mari Carmen surname: Gomez-Cabrera fullname: Gomez-Cabrera, Mari Carmen organization: Freshage Research Group, Department of Physiology Faculty of Medicine, University of Valencia and CIBERFES. Fundación Investigación Hospital Clínico Universitario/INCLIVA, Valencia, Spain – sequence: 6 givenname: Zsolt surname: Radak fullname: Radak, Zsolt organization: Research Institute of Sport Science, University of Physical Education, Budapest, Hungary – sequence: 7 givenname: Istvan surname: Berkes fullname: Berkes, Istvan organization: Research Institute of Sport Science, University of Physical Education, Budapest, Hungary – sequence: 8 givenname: Anita surname: Boros fullname: Boros, Anita organization: National University of Public Service, Budapest, Hungary – sequence: 9 givenname: Istvan surname: Boldogh fullname: Boldogh, Istvan organization: Department of Microbiology and Immunology, University of Texas Medical Branch at Galveston, USA – sequence: 10 givenname: Christiaan surname: Leeuwenburgh fullname: Leeuwenburgh, Christiaan organization: Institute on Aging, College of Medicine, University of Florida, Gainesville, USA – sequence: 11 givenname: Hélio José surname: Coelho-Júnior fullname: Coelho-Júnior, Hélio José organization: Università Cattolica Del Sacro Cuore, Rome, Italy – sequence: 12 givenname: Emanuele surname: Marzetti fullname: Marzetti, Emanuele organization: Fondazione Policlinico Universitario “Agostino Gemelli” IRCCS, Università Cattolica Del Sacro Cuore, Rome, Italy – sequence: 13 givenname: Ying surname: Cheng fullname: Cheng, Ying organization: Center for Mitochondrial Biology and Medicine, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China – sequence: 14 givenname: Jiankang surname: Liu fullname: Liu, Jiankang organization: Center for Mitochondrial Biology and Medicine, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China – sequence: 15 givenname: J. Larry surname: Durstine fullname: Durstine, J. Larry organization: Department of Exercise Science, Norman J. Arnold School of Public Health, University of South Carolina, Columbia, USA – sequence: 16 givenname: Junzhi surname: Sun fullname: Sun, Junzhi organization: Institute of Sports Medicine and Health, Chengdu Sport University, Chengdu, China – sequence: 17 givenname: Li Li surname: Ji fullname: Ji, Li Li email: llji@umn.edu organization: The Laboratory of Physiological Hygiene and Exercise Science, School of Kinesiology, University of Minnesota Twin Cities, Minneapolis, USA |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/34189484$$D View this record in MEDLINE/PubMed |
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