ATF2, a paradigm of the multifaceted regulation of transcription factors in biology and disease

[Display omitted] Stringent transcriptional regulation is crucial for normal cellular biology and organismal development. Perturbations in the proper regulation of transcription factors can result in numerous pathologies, including cancer. Thus, understanding how transcription factors are regulated...

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Bibliographic Details
Published in:	Pharmacological research Vol. 119; pp. 347 - 357
Main Authors:	Watson, Gregory, Ronai, Ze’ev A., Lau, Eric
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Ltd 01.05.2017
Subjects:	Activating Transcription Factor 2 (ATF2) Activating Transcription Factor 2 - analysis Activating Transcription Factor 2 - genetics Activating Transcription Factor 2 - metabolism Activator Protein 1 (AP1) Animals Cancer Drug Discovery Humans Neoplasms - drug therapy Neoplasms - genetics Neoplasms - metabolism Protein Processing, Post-Translational Signal transduction Transcription factor Transcriptional Activation Signal transduction Activating Transcription Factor 2 (ATF2) Activator Protein 1 (AP1) Transcription factor Cancer
ISSN:	1043-6618, 1096-1186
Online Access:	Get full text
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