Image fusion of mass spectrometry and microscopy: a multimodality paradigm for molecular tissue mapping

An approach to fuse images from imaging mass spectrometry and microscopy provides biological insights into molecular tissue distributions beyond what can be obtained from either modality individually. We describe a predictive imaging modality created by 'fusing' two distinct technologies:...

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Bibliographic Details
Published in:	Nature methods Vol. 12; no. 4; pp. 366 - 372
Main Authors:	Van de Plas, Raf, Yang, Junhai, Spraggins, Jeffrey, Caprioli, Richard M
Format:	Journal Article
Language:	English
Published:	New York Nature Publishing Group US 01.04.2015 Nature Publishing Group
Subjects:	631/114/1564 631/114/2401 631/1647/245/2160 631/1647/527/296 82/58 Animals Bioinformatics Biological Microscopy Biological Techniques Biomedical and Life Sciences Biomedical Engineering/Biotechnology Brain - ultrastructure Fusion Genetic research Genetic screening Heterogeneity Image Processing, Computer-Assisted - instrumentation Image Processing, Computer-Assisted - methods Innovations Life Sciences Light microscopy Mass Spectrometry Methods Mice Microscope and microscopy Microscopy Molecular biology Proteomics Tissues
ISSN:	1548-7091, 1548-7105, 1548-7105
Online Access:	Get full text
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