Plasma granulysin levels and cellular interferon-γ production correlate with curative host responses in tuberculosis, while plasma interferon-γ levels correlate with tuberculosis disease activity in adults
Granulysin is a recently identified cytolytic protein which is expressed by human cytotoxic T-lymphocytes and natural killer (NK)-cells, and has broad antimicrobial and tumoricidal activity. Circulating granulysin levels are associated with T- and NK-cell activity, and may thus reflect protection-as...
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| Vydané v: | Tuberculosis (Edinburgh, Scotland) Ročník 87; číslo 4; s. 312 - 321 |
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| Hlavní autori: | , , , , , , , , , , , , |
| Médium: | Journal Article |
| Jazyk: | English |
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Scotland
Elsevier Ltd
01.07.2007
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| ISSN: | 1472-9792 |
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| Abstract | Granulysin is a recently identified cytolytic protein which is expressed by human cytotoxic T-lymphocytes and natural killer (NK)-cells, and has broad antimicrobial and tumoricidal activity. Circulating granulysin levels are associated with T- and NK-cell activity, and may thus reflect protection-associated cellular immune responses. In a case-control study in Indonesia, a highly tuberculosis (TB)-endemic country, we therefore determined plasma granulysin levels in adults with active pulmonary TB before, during, and after TB treatment, both in mild/moderate-TB and advanced-TB patients, and compared these to healthy neighbourhood controls. Adults with active pulmonary TB had significantly lower plasma granulysin levels compared to controls. After 2 months of anti-TB therapy, levels in TB patients had significantly increased, reaching values similar to those in controls. Plasma granulysin levels further increased after completion of TB therapy, being significantly higher than those in controls. Plasma granulysin levels correlated inversely with TB disease activity but not with TB disease severity. In contrast, plasma interferon-γ (IFN-γ) levels were significantly higher in active TB cases than in controls, normalised during treatment and correlated with both TB disease activity and TB disease severity.
At the cellular level, granulysin and IFN-γ expression both correlated inversely with disease activity. Interestingly, granulysin was predominantly expressed by IFN-γ negative T-cells, suggesting that the cellular sources of IFN-γ and granulysin in TB are partly non-overlapping.
The observation that plasma granulysin levels and cellular IFN-γ production correlate with curative host responses in pulmonary tuberculosis points to a potentially important role of granulysin, next to IFN-γ, in host defence against M. tuberculosis. |
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| AbstractList | Granulysin is a recently identified cytolytic protein which is expressed by human cytotoxic T-lymphocytes and natural killer (NK)-cells, and has broad antimicrobial and tumoricidal activity. Circulating granulysin levels are associated with T- and NK-cell activity, and may thus reflect protection-associated cellular immune responses. In a case-control study in Indonesia, a highly tuberculosis (TB)-endemic country, we therefore determined plasma granulysin levels in adults with active pulmonary TB before, during, and after TB treatment, both in mild/moderate-TB and advanced-TB patients, and compared these to healthy neighbourhood controls. Adults with active pulmonary TB had significantly lower plasma granulysin levels compared to controls. After 2 months of anti-TB therapy, levels in TB patients had significantly increased, reaching values similar to those in controls. Plasma granulysin levels further increased after completion of TB therapy, being significantly higher than those in controls. Plasma granulysin levels correlated inversely with TB disease activity but not with TB disease severity. In contrast, plasma interferon-γ (IFN-γ) levels were significantly higher in active TB cases than in controls, normalised during treatment and correlated with both TB disease activity and TB disease severity.
At the cellular level, granulysin and IFN-γ expression both correlated inversely with disease activity. Interestingly, granulysin was predominantly expressed by IFN-γ negative T-cells, suggesting that the cellular sources of IFN-γ and granulysin in TB are partly non-overlapping.
The observation that plasma granulysin levels and cellular IFN-γ production correlate with curative host responses in pulmonary tuberculosis points to a potentially important role of granulysin, next to IFN-γ, in host defence against M. tuberculosis. Granulysin is a recently identified cytolytic protein which is expressed by human cytotoxic T-lymphocytes and natural killer (NK)-cells, and has broad antimicrobial and tumoricidal activity. Circulating granulysin levels are associated with T- and NK-cell activity, and may thus reflect protection- associated cellular immune responses. In a case-control study in Indonesia, a highly tuberculosis (TB)-endemic country, we therefore determined plasma granulysin levels in adults with active pulmonary TB before, during, and after TB treatment, both in mild/moderate-TB and advanced-TB patients, and compared these to healthy neighbourhood controls. Adults with active pulmonary TB had significantly lower plasma granulysin levels compared to controls. After 2 months of anti-TB therapy, levels in TB patients had significantly increased, reaching values similar to those in controls. Plasma granulysin levels further increased after completion of TB therapy, being significantly higher than those in controls. Plasma granulysin levels correlated inversely with TB disease activity but not with TB disease severity. In contrast, plasma interferon- gamma (IFN- gamma ) levels were significantly higher in active TB cases than in controls, normalised during treatment and correlated with both TB disease activity and TB disease severity. At the cellular level, granulysin and IFN- gamma expression both correlated inversely with disease activity. Interestingly, granulysin was predominantly expressed by IFN- gamma negative T-cells, suggesting that the cellular sources of IFN- gamma and granulysin in TB are partly non- overlapping. The observation that plasma granulysin levels and cellular IFN- gamma production correlate with curative host responses in pulmonary tuberculosis points to a potentially important role of granulysin, next to IFN- gamma , in host defence against M. tuberculosis. Summary Granulysin is a recently identified cytolytic protein which is expressed by human cytotoxic T-lymphocytes and natural killer (NK)-cells, and has broad antimicrobial and tumoricidal activity. Circulating granulysin levels are associated with T- and NK-cell activity, and may thus reflect protection-associated cellular immune responses. In a case-control study in Indonesia, a highly tuberculosis (TB)-endemic country, we therefore determined plasma granulysin levels in adults with active pulmonary TB before, during, and after TB treatment, both in mild/moderate-TB and advanced-TB patients, and compared these to healthy neighbourhood controls. Adults with active pulmonary TB had significantly lower plasma granulysin levels compared to controls. After 2 months of anti-TB therapy, levels in TB patients had significantly increased, reaching values similar to those in controls. Plasma granulysin levels further increased after completion of TB therapy, being significantly higher than those in controls. Plasma granulysin levels correlated inversely with TB disease activity but not with TB disease severity. In contrast, plasma interferon- γ (IFN- γ ) levels were significantly higher in active TB cases than in controls, normalised during treatment and correlated with both TB disease activity and TB disease severity. At the cellular level, granulysin and IFN- γ expression both correlated inversely with disease activity. Interestingly, granulysin was predominantly expressed by IFN- γ negative T-cells, suggesting that the cellular sources of IFN- γ and granulysin in TB are partly non-overlapping. The observation that plasma granulysin levels and cellular IFN- γ production correlate with curative host responses in pulmonary tuberculosis points to a potentially important role of granulysin, next to IFN- γ , in host defence against M. tuberculosis. Granulysin is a recently identified cytolytic protein which is expressed by human cytotoxic T-lymphocytes and natural killer (NK)-cells, and has broad antimicrobial and tumoricidal activity. Circulating granulysin levels are associated with T- and NK-cell activity, and may thus reflect protection-associated cellular immune responses. In a case-control study in Indonesia, a highly tuberculosis (TB)-endemic country, we therefore determined plasma granulysin levels in adults with active pulmonary TB before, during, and after TB treatment, both in mild/moderate-TB and advanced-TB patients, and compared these to healthy neighbourhood controls. Adults with active pulmonary TB had significantly lower plasma granulysin levels compared to controls. After 2 months of anti-TB therapy, levels in TB patients had significantly increased, reaching values similar to those in controls. Plasma granulysin levels further increased after completion of TB therapy, being significantly higher than those in controls. Plasma granulysin levels correlated inversely with TB disease activity but not with TB disease severity. In contrast, plasma interferon-gamma (IFN-gamma) levels were significantly higher in active TB cases than in controls, normalised during treatment and correlated with both TB disease activity and TB disease severity. At the cellular level, granulysin and IFN-gamma expression both correlated inversely with disease activity. Interestingly, granulysin was predominantly expressed by IFN-gamma negative T-cells, suggesting that the cellular sources of IFN-gamma and granulysin in TB are partly non-overlapping. The observation that plasma granulysin levels and cellular IFN-gamma production correlate with curative host responses in pulmonary tuberculosis points to a potentially important role of granulysin, next to IFN-gamma, in host defence against M. tuberculosis.Granulysin is a recently identified cytolytic protein which is expressed by human cytotoxic T-lymphocytes and natural killer (NK)-cells, and has broad antimicrobial and tumoricidal activity. Circulating granulysin levels are associated with T- and NK-cell activity, and may thus reflect protection-associated cellular immune responses. In a case-control study in Indonesia, a highly tuberculosis (TB)-endemic country, we therefore determined plasma granulysin levels in adults with active pulmonary TB before, during, and after TB treatment, both in mild/moderate-TB and advanced-TB patients, and compared these to healthy neighbourhood controls. Adults with active pulmonary TB had significantly lower plasma granulysin levels compared to controls. After 2 months of anti-TB therapy, levels in TB patients had significantly increased, reaching values similar to those in controls. Plasma granulysin levels further increased after completion of TB therapy, being significantly higher than those in controls. Plasma granulysin levels correlated inversely with TB disease activity but not with TB disease severity. In contrast, plasma interferon-gamma (IFN-gamma) levels were significantly higher in active TB cases than in controls, normalised during treatment and correlated with both TB disease activity and TB disease severity. At the cellular level, granulysin and IFN-gamma expression both correlated inversely with disease activity. Interestingly, granulysin was predominantly expressed by IFN-gamma negative T-cells, suggesting that the cellular sources of IFN-gamma and granulysin in TB are partly non-overlapping. The observation that plasma granulysin levels and cellular IFN-gamma production correlate with curative host responses in pulmonary tuberculosis points to a potentially important role of granulysin, next to IFN-gamma, in host defence against M. tuberculosis. |
| Author | van de Vosse, E. Ottenhoff, T.H.M. Di Liberto, D. van Crevel, R. Sahiratmadja, E. Buccheri, S. de Boer, T. van Meijgaarden, K.E. Nelwan, R.H.H. Adnan, I. Klein, M.R. Alisjahbana, B. Dieli, F. |
| Author_xml | – sequence: 1 givenname: E. surname: Sahiratmadja fullname: Sahiratmadja, E. organization: Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands – sequence: 2 givenname: B. surname: Alisjahbana fullname: Alisjahbana, B. organization: Division of Tropical and Infectious Diseases, Department of Internal Medicine, Faculty of Medicine University of Padjadjaran, Bandung 40161, Indonesia – sequence: 3 givenname: S. surname: Buccheri fullname: Buccheri, S. organization: Dipartimento di Biopatologia, Università di Palermo, 90134 Palermo, Italy – sequence: 4 givenname: D. surname: Di Liberto fullname: Di Liberto, D. organization: Dipartimento di Biopatologia, Università di Palermo, 90134 Palermo, Italy – sequence: 5 givenname: T. surname: de Boer fullname: de Boer, T. organization: Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands – sequence: 6 givenname: I. surname: Adnan fullname: Adnan, I. organization: Eijkman Institute for Molecular Biology, Jakarta 10430, Indonesia – sequence: 7 givenname: R. surname: van Crevel fullname: van Crevel, R. organization: Department of Internal Medicine, Radboud University Nijmegen Medical Center, 6500 HB Nijmegen, the Netherlands – sequence: 8 givenname: M.R. surname: Klein fullname: Klein, M.R. organization: Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands – sequence: 9 givenname: K.E. surname: van Meijgaarden fullname: van Meijgaarden, K.E. organization: Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands – sequence: 10 givenname: R.H.H. surname: Nelwan fullname: Nelwan, R.H.H. organization: Division of Tropical and Infection Diseases, Department of Internal Medicine, Faculty of Medicine University of Indonesia, Jakarta 10430, Indonesia – sequence: 11 givenname: E. surname: van de Vosse fullname: van de Vosse, E. organization: Department of Infectious Diseases, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands – sequence: 12 givenname: F. surname: Dieli fullname: Dieli, F. organization: Dipartimento di Biopatologia, Università di Palermo, 90134 Palermo, Italy – sequence: 13 givenname: T.H.M. surname: Ottenhoff fullname: Ottenhoff, T.H.M. email: t.h.m.ottenhoff@lumc.nl organization: Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands |
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| Cites_doi | 10.1016/S0952-7915(03)00097-9 10.1046/j.1440-1711.2000.00936.x 10.1532/IJH97.05091 10.1126/science.280.5368.1435 10.1016/S0161-5890(99)00063-2 10.1016/S0167-5699(99)01449-8 10.1046/j.1365-2567.1996.512590.x 10.1016/j.clinbiochem.2006.07.008 10.1002/ajh.20570 10.1111/j.1365-2249.2004.02414.x 10.1046/j.1365-2249.1999.00783.x 10.1016/j.trstmh.2005.05.002 10.1046/j.1365-3083.2000.00744.x 10.1128/IAI.67.10.5223-5230.1999 10.1182/blood-2006-03-009720 10.4049/jimmunol.165.11.6463 10.1084/jem.178.6.2249 10.1016/S0960-9822(99)80059-1 10.4049/jimmunol.161.4.1758 10.1164/rccm.200503-411OC 10.1128/IAI.61.8.3482-3489.1993 10.1086/345766 10.1182/blood.V99.9.3302 10.1038/84620 10.1007/s002620100228 10.1056/NEJMoa051424 10.1111/j.1600-6143.2005.00970.x 10.1146/annurev.immunol.19.1.93 10.1016/S1473-3099(04)01203-4 10.1006/smim.1997.0061 10.1002/eji.200323977 10.1126/science.282.5386.121 10.1002/1521-4141(200012)30:12<3689::AID-IMMU3689>3.0.CO;2-4 10.1128/CMR.15.2.294-309.2002 10.1016/S0198-8859(00)00228-7 10.1016/j.tube.2004.09.011 10.1126/science.276.5319.1684 |
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| Keywords | Disease severity Cellular IFN-γ Tuberculosis Cellular granulysin Plasma granulysin Plasma IFN-γ Plasma IFN- γ Cellular IFN- γ |
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| References | Stenger, Rosat, Bloom, Krensky, Modlin (bib34) 1999; 20 van Crevel, Ottenhoff, van der Meer (bib1) 2002; 15 Falk A, O’Connor JB, Pratt PC, Webb WR, Wier JA, and Wolinsky E. Classification of pulmonary tuberculosis. In: Diagnosis standards and classification of tuberculosis, vol. 6, 12th ed. New York: National Tuberculosis and Respiratory Disease Association; 1969. p. 68–76. Kishi, Takamori, Ogawa, Takano, Tomita, Tanigawa (bib21) 2002; 50 Barnes, Lu, Abrams, Wang, Yamamura, Modlin (bib37) 1993; 61 Flynn, Chan (bib2) 2001; 19 Hanson, Kaspar, Poulain, Krensky (bib28) 1999; 36 Antas, Cardoso, Pereira, Franken, Cunha, Klatser (bib30) 2005; 99 World Health Organization. Global tuberculosis control: surveillance, planning, financing. WHO Report 2005. WHO/HTM/TB/2005.349. Geneva: World Health Organization; 2005. Geluk, van Meijgaarden, Franken, Drijfhout, D’Souza, Necker (bib13) 2000; 165 Pages, Berger, Camus, Sanchez-Cabo, Costes, Molidor (bib23) 2005; 353 Zheng CF, Ma L, Jones GJ, Gill MJ, Krensky AM, Kubes P, Mody CH. Cytotoxic CD4+ T cells use granulysin to kill Cryptococcus neoformans and activation of this pathway is defective in HIV patients. Nagasawa, Isoda, Itoh, Kajiwara, Morio, Shimizu (bib40) 2006; 81 Turner, Dockrell (bib9) 1996; 87 Gamen, Hanson, Kaspar, Naval, Krensky, Anel (bib29) 1998; 161 Flynn, Chan, Triebold, Dalton, Stewart, Bloom (bib4) 1993; 178 Ochoa, Stenger, Sieling, Thoma-Uszynski, Sabet, Cho (bib24) 2001; 7 Sarwal, Jani, Chang, Huie, Wang, Salvatierra (bib33) 2001; 62 Smith, Dockrell (bib11) 2000; 78 Nagasawa, Kawamoto, Tsuji, Mizutani (bib22) 2005; 82 Pena, Krensky (bib15) 1997; 9 Sakai, Ogawa, Shiozaki, Yoneda, Sasaki, Nagata (bib19) 2004; 136 Verbon, Juffermans, Van Deventer, Speelman, Van Deutekom, Van Der (bib38) 1999; 115 van de Vosse, Hoeve, Ottenhoff (bib5) 2004; 4 van Pinxteren, Cassidy, Smedegaard, Agger, Andersen (bib8) 2000; 30 Qiu, Saito, Sakai, Ogawa, Nagata, Williams (bib20) 2006; 39 Stenger, Hanson, Teitelbaum, Dewan, Niazi, Froelich (bib16) 1998; 282 Morosini, Meloni, Marone, Paschetto, Uccelli, Pozzi (bib39) 2003; 7 Stenger, Mazzaccaro, Uyemura, Cho, Barnes, Rosat (bib31) 1997; 276 de Jong, Altare, Haagen, Elferink, Boer, Breda Vriesman (bib7) 1998; 280 Carranza, Juarez, Torres, Ellner, Sada, Schwander (bib12) 2006; 173 Krensky, Clayberger (bib17) 2005; 5 Ottenhoff, Verreck, Hoeve, van de Vosse (bib3) 2005; 85 Kaufmann (bib6) 1999; 9 Clayberger, Krensky (bib32) 2003; 15 Dieli, Sireci, Caccamo, Di Sano, Titone, Romano (bib25) 2002; 186 Dieli, Singh, Spallek, Romano, Titone, Sireci (bib36) 2000; 52 Sun, Burton, Lucas (bib35) 2002; 99 Ogawa, Takamori, Suzuki, Nagasawa, Takano, Kasahara (bib18) 2003; 33 Smith, Malin, Pauline, Lukey, Atkinson, Content (bib10) 1999; 67 2006. Stenger (10.1016/j.tube.2007.01.002_bib31) 1997; 276 Smith (10.1016/j.tube.2007.01.002_bib10) 1999; 67 Gamen (10.1016/j.tube.2007.01.002_bib29) 1998; 161 Ottenhoff (10.1016/j.tube.2007.01.002_bib3) 2005; 85 van Pinxteren (10.1016/j.tube.2007.01.002_bib8) 2000; 30 Smith (10.1016/j.tube.2007.01.002_bib11) 2000; 78 Geluk (10.1016/j.tube.2007.01.002_bib13) 2000; 165 10.1016/j.tube.2007.01.002_bib14 Krensky (10.1016/j.tube.2007.01.002_bib17) 2005; 5 Nagasawa (10.1016/j.tube.2007.01.002_bib40) 2006; 81 Stenger (10.1016/j.tube.2007.01.002_bib34) 1999; 20 Turner (10.1016/j.tube.2007.01.002_bib9) 1996; 87 Sarwal (10.1016/j.tube.2007.01.002_bib33) 2001; 62 Kishi (10.1016/j.tube.2007.01.002_bib21) 2002; 50 Qiu (10.1016/j.tube.2007.01.002_bib20) 2006; 39 van Crevel (10.1016/j.tube.2007.01.002_bib1) 2002; 15 van de Vosse (10.1016/j.tube.2007.01.002_bib5) 2004; 4 Pages (10.1016/j.tube.2007.01.002_bib23) 2005; 353 Flynn (10.1016/j.tube.2007.01.002_bib2) 2001; 19 Carranza (10.1016/j.tube.2007.01.002_bib12) 2006; 173 Dieli (10.1016/j.tube.2007.01.002_bib36) 2000; 52 Sakai (10.1016/j.tube.2007.01.002_bib19) 2004; 136 10.1016/j.tube.2007.01.002_bib26 10.1016/j.tube.2007.01.002_bib27 Ogawa (10.1016/j.tube.2007.01.002_bib18) 2003; 33 Nagasawa (10.1016/j.tube.2007.01.002_bib22) 2005; 82 Hanson (10.1016/j.tube.2007.01.002_bib28) 1999; 36 Pena (10.1016/j.tube.2007.01.002_bib15) 1997; 9 Clayberger (10.1016/j.tube.2007.01.002_bib32) 2003; 15 Barnes (10.1016/j.tube.2007.01.002_bib37) 1993; 61 de Jong (10.1016/j.tube.2007.01.002_bib7) 1998; 280 Dieli (10.1016/j.tube.2007.01.002_bib25) 2002; 186 Verbon (10.1016/j.tube.2007.01.002_bib38) 1999; 115 Stenger (10.1016/j.tube.2007.01.002_bib16) 1998; 282 Kaufmann (10.1016/j.tube.2007.01.002_bib6) 1999; 9 Antas (10.1016/j.tube.2007.01.002_bib30) 2005; 99 Morosini (10.1016/j.tube.2007.01.002_bib39) 2003; 7 Sun (10.1016/j.tube.2007.01.002_bib35) 2002; 99 Ochoa (10.1016/j.tube.2007.01.002_bib24) 2001; 7 Flynn (10.1016/j.tube.2007.01.002_bib4) 1993; 178 |
| References_xml | – volume: 15 start-page: 294 year: 2002 end-page: 309 ident: bib1 article-title: Innate immunity to publication-title: Clin Microbiol Rev – reference: Falk A, O’Connor JB, Pratt PC, Webb WR, Wier JA, and Wolinsky E. Classification of pulmonary tuberculosis. In: Diagnosis standards and classification of tuberculosis, vol. 6, 12th ed. New York: National Tuberculosis and Respiratory Disease Association; 1969. p. 68–76. – volume: 61 start-page: 3482 year: 1993 end-page: 3489 ident: bib37 article-title: Cytokine production at the site of disease in human tuberculosis publication-title: Infect Immun – volume: 99 start-page: 3302 year: 2002 end-page: 3309 ident: bib35 article-title: Cytokine production and cytolytic mechanism of CD4(+) cytotoxic T lymphocytes in ex vivo expanded therapeutic Epstein-Barr virus-specific T-cell cultures publication-title: Blood – volume: 19 start-page: 93 year: 2001 end-page: 129 ident: bib2 article-title: Immunology of tuberculosis publication-title: Annu Rev Immunol – volume: 115 start-page: 110 year: 1999 end-page: 113 ident: bib38 article-title: Serum concentrations of cytokines in patients with active tuberculosis (TB) and after treatment publication-title: Clin Exp Immunol – volume: 67 start-page: 5223 year: 1999 end-page: 5230 ident: bib10 article-title: Characterization of human publication-title: Infect Immun – volume: 99 start-page: 699 year: 2005 end-page: 707 ident: bib30 article-title: T cell immune responses to mycobacterial antigens in Brazilian tuberculosis patients and controls publication-title: Trans R Soc Trop Med Hyg – volume: 136 start-page: 114 year: 2004 end-page: 119 ident: bib19 article-title: Serum granulysin is a marker for Th1 type immunity in pre-eclampsia publication-title: Clin Exp Immunol – volume: 30 start-page: 3689 year: 2000 end-page: 3698 ident: bib8 article-title: Control of latent publication-title: Eur J Immunol – reference: Zheng CF, Ma L, Jones GJ, Gill MJ, Krensky AM, Kubes P, Mody CH. Cytotoxic CD4+ T cells use granulysin to kill Cryptococcus neoformans and activation of this pathway is defective in HIV patients. – reference: World Health Organization. Global tuberculosis control: surveillance, planning, financing. WHO Report 2005. WHO/HTM/TB/2005.349. Geneva: World Health Organization; 2005. – reference: 2006. – volume: 161 start-page: 1758 year: 1998 end-page: 1764 ident: bib29 article-title: Granulysin-induced apoptosis. I. Involvement of at least two distinct pathways publication-title: J Immunol – volume: 4 start-page: 739 year: 2004 end-page: 749 ident: bib5 article-title: Human genetics of intracellular infectious diseases: molecular and cellular immunity against mycobacteria and salmonellae publication-title: Lancet Infect Dis – volume: 39 start-page: 1016 year: 2006 end-page: 1021 ident: bib20 article-title: Plasma granulysin concentrations and preeclampsia risk publication-title: Clin Biochem – volume: 82 start-page: 456 year: 2005 end-page: 457 ident: bib22 article-title: Transient increase of serum granulysin in a stage IVs neuroblastoma patient during spontaneous regression: case report publication-title: Int J Hematol – volume: 280 start-page: 1435 year: 1998 end-page: 1438 ident: bib7 article-title: Severe mycobacterial and Salmonella infections in interleukin-12 receptor-deficient patients publication-title: Science – volume: 353 start-page: 2654 year: 2005 end-page: 2666 ident: bib23 article-title: Effector memory T cells, early metastasis, and survival in colorectal cancer publication-title: N Engl J Med – volume: 81 start-page: 340 year: 2006 end-page: 348 ident: bib40 article-title: Analysis of serum granulysin in patients with hematopoietic stem-cell transplantation: its usefulness as a marker of graft-versus-host reaction publication-title: Am J Hematol – volume: 178 start-page: 2249 year: 1993 end-page: 2254 ident: bib4 article-title: An essential role for interferon gamma in resistance to publication-title: J Exp Med – volume: 165 start-page: 6463 year: 2000 end-page: 6471 ident: bib13 article-title: Identification of major epitopes of Mycobacterium tuberculosis AG85B that are recognized by HLA-A*0201-restricted CD8+ T cells in HLA-transgenic mice and humans publication-title: J Immunol – volume: 62 start-page: 21 year: 2001 end-page: 31 ident: bib33 article-title: Granulysin expression is a marker for acute rejection and steroid resistance in human renal transplantation publication-title: Hum Immunol – volume: 85 start-page: 53 year: 2005 end-page: 64 ident: bib3 article-title: Control of human host immunity to mycobacteria publication-title: Tuberculosis – volume: 78 start-page: 325 year: 2000 end-page: 333 ident: bib11 article-title: Role of CD8 T cells in mycobacterial infections publication-title: Immunol Cell Biol – volume: 276 start-page: 1684 year: 1997 end-page: 1687 ident: bib31 article-title: Differential effects of cytolytic T cell subsets on intracellular infection publication-title: Science – volume: 87 start-page: 339 year: 1996 end-page: 342 ident: bib9 article-title: Stimulation of human peripheral blood mononuclear cells with live publication-title: Immunology – volume: 173 start-page: 238 year: 2006 end-page: 245 ident: bib12 article-title: Mycobacterium tuberculosis growth control by lung macrophages and CD8 cells from patient contacts publication-title: Am J Respir Crit Care Med – volume: 36 start-page: 413 year: 1999 end-page: 422 ident: bib28 article-title: Biosynthesis of granulysin, a novel cytolytic molecule publication-title: Mol Immunol – volume: 282 start-page: 121 year: 1998 end-page: 125 ident: bib16 article-title: An antimicrobial activity of cytolytic T cells mediated by granulysin publication-title: Science – volume: 50 start-page: 604 year: 2002 end-page: 614 ident: bib21 article-title: Differential expression of granulysin and perforin by NK cells in cancer patients and correlation of impaired granulysin expression with progression of cancer publication-title: Cancer Immunol Immunother – volume: 7 start-page: 994 year: 2003 end-page: 1000 ident: bib39 article-title: The assessment of IFN-gamma and its regulatory cytokines in the plasma and bronchoalveolar lavage fluid of patients with active pulmonary tuberculosis publication-title: Int J Tuberc Lung Dis – volume: 15 start-page: 560 year: 2003 end-page: 565 ident: bib32 article-title: Granulysin publication-title: Curr Opin Immunol – volume: 9 start-page: 117 year: 1997 end-page: 125 ident: bib15 article-title: Granulysin, a new human cytolytic granule-associated protein with possible involvement in cell-mediated cytotoxicity publication-title: Semin Immunol – volume: 33 start-page: 1925 year: 2003 end-page: 1933 ident: bib18 article-title: Granulysin in human serum as a marker of cell-mediated immunity publication-title: Eur J Immunol – volume: 9 start-page: R97 year: 1999 end-page: R99 ident: bib6 article-title: Cell-mediated immunity: dealing a direct blow to pathogens publication-title: Curr Biol – volume: 5 start-page: 1789 year: 2005 end-page: 1792 ident: bib17 article-title: Granulysin: a novel host defense molecule publication-title: Am J Transplant – volume: 7 start-page: 174 year: 2001 end-page: 179 ident: bib24 article-title: T-cell release of granulysin contributes to host defense in leprosy publication-title: Nat Med – volume: 52 start-page: 96 year: 2000 end-page: 102 ident: bib36 article-title: Change of Th0 to Th1 cell-cytokine profile following tuberculosis chemotherapy publication-title: Scand J Immunol – volume: 186 start-page: 1835 year: 2002 end-page: 1839 ident: bib25 article-title: Selective depression of interferon-gamma and granulysin production with increase of proliferative response by Vgamma9/Vdelta2 T cells in children with tuberculosis publication-title: J Infect Dis – volume: 20 start-page: 390 year: 1999 end-page: 394 ident: bib34 article-title: Granulysin: a lethal weapon of cytolytic T cells publication-title: Immunol Today – volume: 15 start-page: 560 issue: 5 year: 2003 ident: 10.1016/j.tube.2007.01.002_bib32 article-title: Granulysin publication-title: Curr Opin Immunol doi: 10.1016/S0952-7915(03)00097-9 – volume: 78 start-page: 325 issue: 4 year: 2000 ident: 10.1016/j.tube.2007.01.002_bib11 article-title: Role of CD8 T cells in mycobacterial infections publication-title: Immunol Cell Biol doi: 10.1046/j.1440-1711.2000.00936.x – volume: 82 start-page: 456 issue: 5 year: 2005 ident: 10.1016/j.tube.2007.01.002_bib22 article-title: Transient increase of serum granulysin in a stage IVs neuroblastoma patient during spontaneous regression: case report publication-title: Int J Hematol doi: 10.1532/IJH97.05091 – volume: 280 start-page: 1435 issue: 5368 year: 1998 ident: 10.1016/j.tube.2007.01.002_bib7 article-title: Severe mycobacterial and Salmonella infections in interleukin-12 receptor-deficient patients publication-title: Science doi: 10.1126/science.280.5368.1435 – volume: 36 start-page: 413 issue: 7 year: 1999 ident: 10.1016/j.tube.2007.01.002_bib28 article-title: Biosynthesis of granulysin, a novel cytolytic molecule publication-title: Mol Immunol doi: 10.1016/S0161-5890(99)00063-2 – volume: 20 start-page: 390 issue: 9 year: 1999 ident: 10.1016/j.tube.2007.01.002_bib34 article-title: Granulysin: a lethal weapon of cytolytic T cells publication-title: Immunol Today doi: 10.1016/S0167-5699(99)01449-8 – volume: 87 start-page: 339 issue: 3 year: 1996 ident: 10.1016/j.tube.2007.01.002_bib9 article-title: Stimulation of human peripheral blood mononuclear cells with live Mycobacterium bovis BCG activates cytolytic CD8+ T cells in vitro publication-title: Immunology doi: 10.1046/j.1365-2567.1996.512590.x – volume: 7 start-page: 994 issue: 10 year: 2003 ident: 10.1016/j.tube.2007.01.002_bib39 article-title: The assessment of IFN-gamma and its regulatory cytokines in the plasma and bronchoalveolar lavage fluid of patients with active pulmonary tuberculosis publication-title: Int J Tuberc Lung Dis – volume: 39 start-page: 1016 issue: 10 year: 2006 ident: 10.1016/j.tube.2007.01.002_bib20 article-title: Plasma granulysin concentrations and preeclampsia risk publication-title: Clin Biochem doi: 10.1016/j.clinbiochem.2006.07.008 – volume: 81 start-page: 340 issue: 5 year: 2006 ident: 10.1016/j.tube.2007.01.002_bib40 article-title: Analysis of serum granulysin in patients with hematopoietic stem-cell transplantation: its usefulness as a marker of graft-versus-host reaction publication-title: Am J Hematol doi: 10.1002/ajh.20570 – volume: 136 start-page: 114 issue: 1 year: 2004 ident: 10.1016/j.tube.2007.01.002_bib19 article-title: Serum granulysin is a marker for Th1 type immunity in pre-eclampsia publication-title: Clin Exp Immunol doi: 10.1111/j.1365-2249.2004.02414.x – volume: 115 start-page: 110 issue: 1 year: 1999 ident: 10.1016/j.tube.2007.01.002_bib38 article-title: Serum concentrations of cytokines in patients with active tuberculosis (TB) and after treatment publication-title: Clin Exp Immunol doi: 10.1046/j.1365-2249.1999.00783.x – volume: 99 start-page: 699 issue: 9 year: 2005 ident: 10.1016/j.tube.2007.01.002_bib30 article-title: T cell immune responses to mycobacterial antigens in Brazilian tuberculosis patients and controls publication-title: Trans R Soc Trop Med Hyg doi: 10.1016/j.trstmh.2005.05.002 – volume: 52 start-page: 96 issue: 1 year: 2000 ident: 10.1016/j.tube.2007.01.002_bib36 article-title: Change of Th0 to Th1 cell-cytokine profile following tuberculosis chemotherapy publication-title: Scand J Immunol doi: 10.1046/j.1365-3083.2000.00744.x – ident: 10.1016/j.tube.2007.01.002_bib26 – volume: 67 start-page: 5223 issue: 10 year: 1999 ident: 10.1016/j.tube.2007.01.002_bib10 article-title: Characterization of human Mycobacterium bovis bacille Calmette-Guerin-reactive CD8+ T cells publication-title: Infect Immun doi: 10.1128/IAI.67.10.5223-5230.1999 – ident: 10.1016/j.tube.2007.01.002_bib14 doi: 10.1182/blood-2006-03-009720 – volume: 165 start-page: 6463 issue: 11 year: 2000 ident: 10.1016/j.tube.2007.01.002_bib13 article-title: Identification of major epitopes of Mycobacterium tuberculosis AG85B that are recognized by HLA-A*0201-restricted CD8+ T cells in HLA-transgenic mice and humans publication-title: J Immunol doi: 10.4049/jimmunol.165.11.6463 – volume: 178 start-page: 2249 issue: 6 year: 1993 ident: 10.1016/j.tube.2007.01.002_bib4 article-title: An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection publication-title: J Exp Med doi: 10.1084/jem.178.6.2249 – volume: 9 start-page: R97 issue: 3 year: 1999 ident: 10.1016/j.tube.2007.01.002_bib6 article-title: Cell-mediated immunity: dealing a direct blow to pathogens publication-title: Curr Biol doi: 10.1016/S0960-9822(99)80059-1 – volume: 161 start-page: 1758 issue: 4 year: 1998 ident: 10.1016/j.tube.2007.01.002_bib29 article-title: Granulysin-induced apoptosis. I. Involvement of at least two distinct pathways publication-title: J Immunol doi: 10.4049/jimmunol.161.4.1758 – volume: 173 start-page: 238 issue: 2 year: 2006 ident: 10.1016/j.tube.2007.01.002_bib12 article-title: Mycobacterium tuberculosis growth control by lung macrophages and CD8 cells from patient contacts publication-title: Am J Respir Crit Care Med doi: 10.1164/rccm.200503-411OC – volume: 61 start-page: 3482 issue: 8 year: 1993 ident: 10.1016/j.tube.2007.01.002_bib37 article-title: Cytokine production at the site of disease in human tuberculosis publication-title: Infect Immun doi: 10.1128/IAI.61.8.3482-3489.1993 – volume: 186 start-page: 1835 issue: 12 year: 2002 ident: 10.1016/j.tube.2007.01.002_bib25 article-title: Selective depression of interferon-gamma and granulysin production with increase of proliferative response by Vgamma9/Vdelta2 T cells in children with tuberculosis publication-title: J Infect Dis doi: 10.1086/345766 – volume: 99 start-page: 3302 issue: 9 year: 2002 ident: 10.1016/j.tube.2007.01.002_bib35 article-title: Cytokine production and cytolytic mechanism of CD4(+) cytotoxic T lymphocytes in ex vivo expanded therapeutic Epstein-Barr virus-specific T-cell cultures publication-title: Blood doi: 10.1182/blood.V99.9.3302 – volume: 7 start-page: 174 issue: 2 year: 2001 ident: 10.1016/j.tube.2007.01.002_bib24 article-title: T-cell release of granulysin contributes to host defense in leprosy publication-title: Nat Med doi: 10.1038/84620 – volume: 50 start-page: 604 issue: 11 year: 2002 ident: 10.1016/j.tube.2007.01.002_bib21 article-title: Differential expression of granulysin and perforin by NK cells in cancer patients and correlation of impaired granulysin expression with progression of cancer publication-title: Cancer Immunol Immunother doi: 10.1007/s002620100228 – volume: 353 start-page: 2654 issue: 25 year: 2005 ident: 10.1016/j.tube.2007.01.002_bib23 article-title: Effector memory T cells, early metastasis, and survival in colorectal cancer publication-title: N Engl J Med doi: 10.1056/NEJMoa051424 – ident: 10.1016/j.tube.2007.01.002_bib27 – volume: 5 start-page: 1789 issue: 8 year: 2005 ident: 10.1016/j.tube.2007.01.002_bib17 article-title: Granulysin: a novel host defense molecule publication-title: Am J Transplant doi: 10.1111/j.1600-6143.2005.00970.x – volume: 19 start-page: 93 year: 2001 ident: 10.1016/j.tube.2007.01.002_bib2 article-title: Immunology of tuberculosis publication-title: Annu Rev Immunol doi: 10.1146/annurev.immunol.19.1.93 – volume: 4 start-page: 739 issue: 12 year: 2004 ident: 10.1016/j.tube.2007.01.002_bib5 article-title: Human genetics of intracellular infectious diseases: molecular and cellular immunity against mycobacteria and salmonellae publication-title: Lancet Infect Dis doi: 10.1016/S1473-3099(04)01203-4 – volume: 9 start-page: 117 issue: 2 year: 1997 ident: 10.1016/j.tube.2007.01.002_bib15 article-title: Granulysin, a new human cytolytic granule-associated protein with possible involvement in cell-mediated cytotoxicity publication-title: Semin Immunol doi: 10.1006/smim.1997.0061 – volume: 33 start-page: 1925 issue: 7 year: 2003 ident: 10.1016/j.tube.2007.01.002_bib18 article-title: Granulysin in human serum as a marker of cell-mediated immunity publication-title: Eur J Immunol doi: 10.1002/eji.200323977 – volume: 282 start-page: 121 issue: 5386 year: 1998 ident: 10.1016/j.tube.2007.01.002_bib16 article-title: An antimicrobial activity of cytolytic T cells mediated by granulysin publication-title: Science doi: 10.1126/science.282.5386.121 – volume: 30 start-page: 3689 issue: 12 year: 2000 ident: 10.1016/j.tube.2007.01.002_bib8 article-title: Control of latent Mycobacterium tuberculosis infection is dependent on CD8 T cells publication-title: Eur J Immunol doi: 10.1002/1521-4141(200012)30:12<3689::AID-IMMU3689>3.0.CO;2-4 – volume: 15 start-page: 294 issue: 2 year: 2002 ident: 10.1016/j.tube.2007.01.002_bib1 article-title: Innate immunity to Mycobacterium tuberculosis publication-title: Clin Microbiol Rev doi: 10.1128/CMR.15.2.294-309.2002 – volume: 62 start-page: 21 issue: 1 year: 2001 ident: 10.1016/j.tube.2007.01.002_bib33 article-title: Granulysin expression is a marker for acute rejection and steroid resistance in human renal transplantation publication-title: Hum Immunol doi: 10.1016/S0198-8859(00)00228-7 – volume: 85 start-page: 53 issue: 1–2 year: 2005 ident: 10.1016/j.tube.2007.01.002_bib3 article-title: Control of human host immunity to mycobacteria publication-title: Tuberculosis doi: 10.1016/j.tube.2004.09.011 – volume: 276 start-page: 1684 issue: 5319 year: 1997 ident: 10.1016/j.tube.2007.01.002_bib31 article-title: Differential effects of cytolytic T cell subsets on intracellular infection publication-title: Science doi: 10.1126/science.276.5319.1684 |
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| Snippet | Granulysin is a recently identified cytolytic protein which is expressed by human cytotoxic T-lymphocytes and natural killer (NK)-cells, and has broad... Summary Granulysin is a recently identified cytolytic protein which is expressed by human cytotoxic T-lymphocytes and natural killer (NK)-cells, and has broad... |
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| SubjectTerms | Adolescent Adult Aged Antigens, Differentiation, T-Lymphocyte - blood Case-Control Studies Cellular granulysin Cellular IFN-γ Disease severity Enzyme-Linked Immunosorbent Assay Female Humans Immunity, Cellular - physiology Infectious Disease Interferon-gamma - blood Interferon-gamma - metabolism Male Middle Aged Mycobacterium Plasma granulysin Plasma IFN-γ Pulmonary/Respiratory Severity of Illness Index Tuberculosis Tuberculosis, Pulmonary - blood |
| Title | Plasma granulysin levels and cellular interferon-γ production correlate with curative host responses in tuberculosis, while plasma interferon-γ levels correlate with tuberculosis disease activity in adults |
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