Dissociation of periodic leg movements from arousals in restless legs syndrome

Objective: The purpose of this study was to characterize the nature of the relation between periodic leg movements during sleep (PLMS) and cortical arousals to contribute to the debate on the clinical significance and treatment of PLMS. Methods: A prospective, placebo‐controlled, single‐blind, paral...

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Bibliographic Details
Published in:	Annals of neurology Vol. 71; no. 6; pp. 834 - 844
Main Authors:	Manconi, Mauro, Ferri, Raffaele, Zucconi, Marco, Bassetti, Claudio L., Fulda, Stephany, Aricò, Debora, Ferini-Strambi, Luigi
Format:	Journal Article
Language:	English
Published:	Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.06.2012 Wiley-Liss Wiley Subscription Services, Inc
Subjects:	Anticonvulsants - therapeutic use Antiparkinson Agents - therapeutic use Arousal - drug effects Arousal - physiology Benzothiazoles - therapeutic use Biological and medical sciences Clonazepam - therapeutic use Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes Electroencephalography Female Humans Leg - physiopathology Male Medical research Medical sciences Movement - drug effects Movement - physiology Nervous system (semeiology, syndromes) Neurology Pain Measurement Periodicity Polysomnography Prospective Studies Restless legs syndrome Restless Legs Syndrome - drug therapy Restless Legs Syndrome - pathology Restless Legs Syndrome - physiopathology Single-Blind Method Sleep deprivation Sensitivity disorder Restless legs syndrome Nervous system diseases Neurological disorder Arousal
ISSN:	0364-5134, 1531-8249, 1531-8249
Online Access:	Get full text
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