Percutaneous absorption of vanilloids: in vivo and in vitro studies

The percutaneous absorption of three highly lipophilic analogs of capsaicin--vanillylnonanamide (VN), olvanil, and NE-21610--was measured in vivo in the CD:VAF rat, and in vitro through excised CD: VAF and SkH:Fz rat skin and human cadaver skin. Absorption and skin metabolism were monitored by radio...

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Bibliographic Details

Published in:	Journal of pharmaceutical sciences Vol. 86; no. 1; p. 142
Main Authors:	Kasting, G B, Francis, W R, Bowman, L A, Kinnett, G O
Format:	Journal Article
Language:	English
Published:	United States 01.01.1997
Subjects:	Animals Capsaicin - analogs & derivatives Capsaicin - pharmacokinetics Humans In Vitro Techniques Male Rats Skin Absorption Vanillic Acid - analogs & derivatives Vanillic Acid - pharmacokinetics
ISSN:	0022-3549
Online Access:	Get more information
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