P-Value Precision and Reproducibility

P-values are useful statistical measures of evidence against a null hypothesis. In contrast to other statistical estimates, however, their sample-to-sample variability is usually not considered or estimated, and therefore not fully appreciated. Via a systematic study of log-scale p-value standard er...

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Veröffentlicht in:The American statistician Jg. 65; H. 4; S. 213 - 221
Hauptverfasser: Boos, Dennis D., Stefanski, Leonard A.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Alexandria, VA Taylor & Francis 01.11.2011
American Statistical Association
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ISSN:0003-1305, 1537-2731
Online-Zugang:Volltext
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Zusammenfassung:P-values are useful statistical measures of evidence against a null hypothesis. In contrast to other statistical estimates, however, their sample-to-sample variability is usually not considered or estimated, and therefore not fully appreciated. Via a systematic study of log-scale p-value standard errors, bootstrap prediction bounds, and reproducibility probabilities for future replicate p-values, we show that p-values exhibit surprisingly large variability in typical data situations. In addition to providing context to discussions about the failure of statistical results to replicate, our findings shed light on the relative value of exact p-values vis-a-vis approximate p-values, and indicate that the use of *, **, and *** to denote levels 0.05, 0.01, and 0.001 of statistical significance in subject-matter journals is about the right level of precision for reporting p-values when judged by widely accepted rules for rounding statistical estimates.
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ISSN:0003-1305
1537-2731
DOI:10.1198/tas.2011.10129