Diagnostic Implications of NGS-Based Molecular Profiling in Mature B-Cell Lymphomas with Potential Bone Marrow Involvement

Background: Methods such as cytogenetics and immunocytology/immunohistology provide essential diagnostic insights but may be limited in ambiguous cases of mature B-cell lymphoma. Next-generation sequencing (NGS) has emerged as a potential tool to improve diagnostics. Methods: We validated the analyt...

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Veröffentlicht in:	Diagnostics (Basel) Jg. 15; H. 6; S. 727
Hauptverfasser:	Strasser, Bernhard, Mustafa, Sebastian, Seier, Josef, Wimmer, Erich, Tomasits, Josef
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Switzerland MDPI AG 14.03.2025 MDPI
Schlagworte:	B-cell lymphoma Bone marrow Classification Cytogenetics Decision making Development and progression Ethylenediaminetetraacetic acid Gene mutations Genes Genetic testing Genetics Hybridization Kinases Lymphoma Lymphomas Medical prognosis Medical research Medicine, Experimental molecular diagnostics Morphology Mutation next-generation-sequencing NGS Reproducibility Risk assessment Tumors California United States > US Switzerland molecular diagnostics NGS B-cell lymphoma next-generation-sequencing
ISSN:	2075-4418, 2075-4418
Online-Zugang:	Volltext
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