Role of type I interferons in the activation of autoreactive B cells

Type I interferons (IFNs) are a family of cytokines involved in the defense against viral infections that play a key role in the activation of both the innate and adaptive immune system. IFNs both directly and indirectly enhance the capacity of B lymphocytes to respond to viral challenge and produce...

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Bibliographic Details

Published in:	Immunology and cell biology Vol. 90; no. 5; pp. 498 - 504
Main Authors:	Kiefer, Kerstin, Oropallo, Michael A, Cancro, Michael P, Marshak‐Rothstein, Ann
Format:	Journal Article
Language:	English
Published:	United States Nature Publishing Group 01.05.2012 Blackwell Science Ltd
Subjects:	Adaptive Immunity Animals Autoimmune Diseases - immunology Autoimmunity B cell B-Cell Activating Factor - immunology B-Lymphocytes - immunology Cell Survival - immunology Humans Immunity, Innate Interferon Type I - immunology Lymphocyte Activation SLE type I IFN Virus Diseases - immunology
ISSN:	0818-9641, 1440-1711, 1440-1711
Online Access:	Get full text
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