Genetic contributions to brain serotonin transporter levels in healthy adults

The serotonin transporter (5-HTT) critically shapes serotonin neurotransmission by regulating extracellular brain serotonin levels; it remains unclear to what extent 5-HTT levels in the human brain are genetically determined. Here we applied [ 11 C]DASB positron emission tomography to image brain 5-...

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Vydané v:	Scientific reports Ročník 13; číslo 1; s. 16426 - 11
Hlavní autori:	Bruzzone, Silvia Elisabetta Portis, Nasser, Arafat, Aripaka, Sagar Sanjay, Spies, Marie, Ozenne, Brice, Jensen, Peter Steen, Knudsen, Gitte Moos, Frokjaer, Vibe Gedsoe, Fisher, Patrick MacDonald
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	London Nature Publishing Group UK 30.09.2023 Nature Publishing Group Nature Portfolio
Predmet:	631/378/2583 631/378/2587 631/378/548/1964 Amygdala Brain Brain-derived neurotrophic factor Genetic diversity Genetic variance Genotypes Homozygotes Humanities and Social Sciences Mesencephalon multidisciplinary Neocortex Neuroimaging Neurotransmission Positron emission tomography Prediction models Putamen Science Science (multidisciplinary) Serotonin Serotonin transporter Statistical analysis Thalamus
ISSN:	2045-2322, 2045-2322
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