Cooler: scalable storage for Hi-C data and other genomically labeled arrays

Abstract Motivation Most existing coverage-based (epi)genomic datasets are one-dimensional, but newer technologies probing interactions (physical, genetic, etc.) produce quantitative maps with two-dimensional genomic coordinate systems. Storage and computational costs mount sharply with data resolut...

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Bibliographic Details
Published in:Bioinformatics Vol. 36; no. 1; pp. 311 - 316
Main Authors: Abdennur, Nezar, Mirny, Leonid A
Format: Journal Article
Language:English
Published: England Oxford University Press 01.01.2020
Subjects:
ISSN:1367-4803, 1367-4811, 1460-2059, 1367-4811
Online Access:Get full text
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