Emerging role of long noncoding RNAs as regulators of innate immune cell development and inflammatory gene expression

The innate immune system represents the first line of defense during infection and is initiated by the detection of conserved microbial products by germline‐encoded pattern recognition receptors (PRRs). Sensing through PRRs induces broad transcriptional changes that elicit powerful inflammatory resp...

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Bibliographic Details
Published in:	European journal of immunology Vol. 46; no. 3; pp. 504 - 512
Main Authors:	Elling, Roland, Chan, Jennie, Fitzgerald, Katherine A.
Format:	Journal Article
Language:	English
Published:	Germany Wiley Subscription Services, Inc 01.03.2016
Subjects:	Cell Nucleus - genetics CRISPR-Cas Systems - genetics Gene Deletion Gene expression Gene Expression Regulation Gene expression · Immune regulation · Inflammation · Innate immunity · (Long) noncoding RNA Immunity, Innate Inflammation - genetics MicroRNAs - genetics Receptors, Pattern Recognition - genetics Receptors, Pattern Recognition - immunology RNA Interference RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism Transcription Factors - genetics Gene expression · Immune regulation · Inflammation · Innate immunity · (Long) noncoding RNA
ISSN:	0014-2980, 1521-4141
Online Access:	Get full text
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