Emerging role of long noncoding RNAs as regulators of innate immune cell development and inflammatory gene expression

The innate immune system represents the first line of defense during infection and is initiated by the detection of conserved microbial products by germline‐encoded pattern recognition receptors (PRRs). Sensing through PRRs induces broad transcriptional changes that elicit powerful inflammatory resp...

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Vydáno v:	European journal of immunology Ročník 46; číslo 3; s. 504 - 512
Hlavní autoři:	Elling, Roland, Chan, Jennie, Fitzgerald, Katherine A.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Germany Wiley Subscription Services, Inc 01.03.2016
Témata:	Cell Nucleus - genetics CRISPR-Cas Systems - genetics Gene Deletion Gene expression Gene Expression Regulation Gene expression · Immune regulation · Inflammation · Innate immunity · (Long) noncoding RNA Immunity, Innate Inflammation - genetics MicroRNAs - genetics Receptors, Pattern Recognition - genetics Receptors, Pattern Recognition - immunology RNA Interference RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism Transcription Factors - genetics Gene expression · Immune regulation · Inflammation · Innate immunity · (Long) noncoding RNA
ISSN:	0014-2980, 1521-4141
On-line přístup:	Získat plný text
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