Angiopoietin 2 induces cell cycle arrest in endothelial cells: a possible mechanism involved in advanced plaque neovascularization

To characterize the molecules and the mechanisms regulating the neoangiogenetic process in advanced atherosclerotic plaques. Western blot and immunofluorescence analysis of atherosclerotic specimens demonstrated that unlike neovessels from early lesions that expressed vascular endothelial growth fac...

Celý popis

Uložené v:

Podrobná bibliografia
Vydané v:	Arteriosclerosis, thrombosis, and vascular biology Ročník 24; číslo 3; s. 511
Hlavní autori:	Calvi, Cristina, Dentelli, Patrizia, Pagano, Marco, Rosso, Arturo, Pegoraro, Marco, Giunti, Sara, Garbarino, Giovanni, Camussi, Giovanni, Pegoraro, Luigi, Brizzi, Maria Felice
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.03.2004
Predmet:	Angiopoietin-1 - biosynthesis Angiopoietin-1 - genetics Angiopoietin-1 - physiology Angiopoietin-2 - biosynthesis Angiopoietin-2 - genetics Angiopoietin-2 - pharmacology Angiopoietin-2 - physiology Arteriosclerosis - pathology Carotid Arteries - metabolism Carotid Arteries - pathology Carotid Artery Diseases - pathology Cell Cycle - drug effects Cell Cycle Proteins - biosynthesis Cell Cycle Proteins - genetics Cell Line, Tumor - metabolism Cells, Cultured - drug effects Cells, Cultured - metabolism Coronary Artery Disease - pathology Coronary Vessels - metabolism Coronary Vessels - pathology Cyclin-Dependent Kinase Inhibitor p21 Disease Progression DNA-Binding Proteins - genetics DNA-Binding Proteins - physiology Endothelial Cells - cytology Endothelial Cells - drug effects Endothelium, Vascular - pathology G1 Phase - drug effects Gene Expression Regulation - drug effects Gene Expression Regulation - physiology Humans Macromolecular Substances Milk Proteins - genetics Neovascularization, Physiologic - drug effects Neovascularization, Physiologic - physiology Proliferating Cell Nuclear Antigen - biosynthesis Proliferating Cell Nuclear Antigen - genetics Receptor, TIE-2 - physiology Signal Transduction - drug effects STAT5 Transcription Factor Trans-Activators - genetics Trans-Activators - physiology Transcription, Genetic Transfection Tunica Intima - pathology
ISSN:	1524-4636, 1524-4636
On-line prístup:	Zistit podrobnosti o prístupe
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!

Buďte prvý, kto okomentuje tento záznam!