The NLRP3 inflammasome and the emerging role of colchicine to inhibit atherosclerosis-associated inflammation

Atherosclerosis is considered a chronic inflammatory disease of the arterial wall. Recently, compelling evidence has arisen for the role of monocytes and neutrophils and a particular protein complex that resides within these cells – the NLRP3 inflammasome – in atherosclerosis-associated inflammation...

Full description

Saved in:

Bibliographic Details
Published in:	Atherosclerosis Vol. 269; pp. 262 - 271
Main Authors:	Martínez, Gonzalo J., Celermajer, David S., Patel, Sanjay
Format:	Journal Article
Language:	English
Published:	Ireland Elsevier B.V 01.02.2018
Subjects:	Acute coronary syndrome Animals Anti-Inflammatory Agents - therapeutic use Arteries - drug effects Arteries - metabolism Arteries - pathology Atherosclerosis Atherosclerosis - drug therapy Atherosclerosis - metabolism Atherosclerosis - pathology Colchicine Colchicine - therapeutic use Cytokines - metabolism Humans Inflammasome Inflammasomes - antagonists & inhibitors Inflammasomes - metabolism Inflammation Inflammation - drug therapy Inflammation - metabolism Inflammation - pathology Inflammation Mediators - metabolism Macrophages - drug effects Macrophages - metabolism Monocytes - drug effects Monocytes - metabolism Myocardial infarction Neutrophils - drug effects Neutrophils - metabolism NLR Family, Pyrin Domain-Containing 3 Protein - antagonists & inhibitors NLR Family, Pyrin Domain-Containing 3 Protein - metabolism Plaque, Atherosclerotic Signal Transduction - drug effects Myocardial infarction Inflammation Inflammasome Colchicine Acute coronary syndrome Atherosclerosis
ISSN:	0021-9150, 1879-1484, 1879-1484
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!