Airway Thiol-NO Adducts as Determinants of Exhaled NO

Thiol-NO adducts such as S-nitrosoglutathione (GSNO) are endogenous bronchodilators in human airways. Decreased airway S-nitrosothiol concentrations are associated with asthma. Nitric oxide (NO), a breakdown product of GSNO, is measured in exhaled breath as a biomarker in asthma; an elevated fractio...

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Veröffentlicht in:	Antioxidants Jg. 10; H. 10; S. 1527
Hauptverfasser:	Pophal, Megan, Grimmett, Zachary W., Chu, Clara, Margevicius, Seunghee, Raffay, Thomas, Ross, Kristie, Jafri, Anjum, Giddings, Olivia, Stamler, Jonathan S., Gaston, Benjamin, Reynolds, James D.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Switzerland MDPI AG 26.09.2021 MDPI
Schlagworte:	Adducts Asthma biomarkers bronchodilators Cardiovascular disease catabolism Clinical trials evolution GSNO reductase humans Hypotheses inflammation Informed consent Laboratory animals Lungs Nitric oxide oxidoreductases Pediatrics Respiratory tract Respiratory tract diseases S-nitrosoglutathione Smooth muscle Spirometry Ventilators United States > US nitric oxide asthma GSNO reductase S-nitrosoglutathione
ISSN:	2076-3921, 2076-3921
Online-Zugang:	Volltext
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