Apoptosis in Skeletal Myocytes: A Potential Target for Interventions against Sarcopenia and Physical Frailty – A Mini-Review

Background: Sarcopenia, the age-related loss of muscle mass and function, represents a relevant public health issue due to its high prevalence and detrimental consequences. While the exact mechanisms underlying the pathogenesis of sarcopenia are not clear, growing experimental evidence indicates tha...

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Bibliographic Details
Published in:	Gerontology (Basel) Vol. 58; no. 2; pp. 99 - 106
Main Authors:	Marzetti, Emanuele, Calvani, Riccardo, Bernabei, Roberto, Leeuwenburgh, Christiaan
Format:	Journal Article
Language:	English
Published:	Basel, Switzerland Karger 01.02.2012 S. Karger AG
Subjects:	Age Age differences Aged Aging Animals Antibodies Apoptosis Apoptosis - drug effects Apoptosis - genetics Apoptosis - physiology Atrophy Biological and medical sciences Caloric Restriction Cell Nucleus - pathology Cells Clinical Section / Mini-Review Development. Metamorphosis. Moult. Ageing Diet Drug therapy Drugs Elimination Exercise Exercise Therapy Frail Elderly Frailty Function Fundamental and applied biological sciences. Psychology Genetics Hormones Humans Intervention Literature reviews Models, Biological Morality Muscle Fibers, Skeletal - drug effects Muscle Fibers, Skeletal - pathology Muscle Fibers, Skeletal - physiology Musculoskeletal diseases Novels Physical ability Preservation Property Public health Sarcopenia Sarcopenia - pathology Sarcopenia - physiopathology Sarcopenia - prevention & control Sarcopenia - therapy Signal Transduction - physiology Signaling Vertebrates: anatomy and physiology, studies on body, several organs or systems Angiotensin-converting enzyme inhibitors Mitochondria Exercise Calorie restriction Resveratrol Muscle Hormones Physical exercise Senescence Enzyme inhibitor Review Antioxidant Striated muscle Stilbene derivatives Myocyte Sarcopenia Renin angiotensin system Vertebrata Mammalia Angiotensin Apoptosis
ISSN:	0304-324X, 1423-0003, 1423-0003
Online Access:	Get full text
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