More than 18,000 effectors in the Legionella genus genome provide multiple, independent combinations for replication in human cells

The genus comprises 65 species, among which is a human pathogen causing severe pneumonia. To understand the evolution of an environmental to an accidental human pathogen, we have functionally analyzed 80 genomes spanning 58 species. Uniquely, an immense repository of 18,000 secreted proteins encodin...

Celý popis

Uložené v:

Podrobná bibliografia
Vydané v:	Proceedings of the National Academy of Sciences - PNAS Ročník 116; číslo 6; s. 2265
Hlavní autori:	Gomez-Valero, Laura, Rusniok, Christophe, Carson, Danielle, Mondino, Sonia, Pérez-Cobas, Ana Elena, Rolando, Monica, Pasricha, Shivani, Reuter, Sandra, Demirtas, Jasmin, Crumbach, Johannes, Descorps-Declere, Stephane, Hartland, Elizabeth L, Jarraud, Sophie, Dougan, Gordon, Schroeder, Gunnar N, Frankel, Gad, Buchrieser, Carmen
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 05.02.2019
Predmet:	Bacterial Proteins - chemistry Bacterial Proteins - genetics Bacterial Secretion Systems - genetics Computational Biology - methods Evolution, Molecular Genome, Bacterial Genomics - methods Humans Intracellular Space - microbiology Legionella - classification Legionella - physiology Legionellosis - microbiology Phylogeny Protein Domains Legionella human pathogen horizontal gene transfer coevolution protozoa
ISSN:	1091-6490, 1091-6490
On-line prístup:	Zistit podrobnosti o prístupe
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!

Buďte prvý, kto okomentuje tento záznam!