Prophylactic furosemide to prevent transfusion-associated circulatory overload: a randomized controlled study in rats

Transfusion-associated circulatory overload (TACO) is the leading cause of transfusion related morbidity and mortality. The only treatment is empirical use of furosemide. Our aim was to investigate if furosemide can prevent TACO. A randomized controlled trial was performed using a previously validat...

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Bibliographic Details
Published in:	Scientific reports Vol. 12; no. 1; pp. 12127 - 9
Main Authors:	Klanderman, Robert B., Bosboom, Joachim J., Veelo, Denise P., Roelofs, Joris J. T. H., de Korte, Dirk, van Bruggen, Robin, Vogt, Liffert, van Buul, Jaap D., Hollmann, Markus W., Vroom, Margreeth B., Juffermans, Nicole P., Geerts, Bart F., Vlaar, Alexander P. J.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 15.07.2022 Nature Publishing Group Nature Portfolio
Subjects:	692/1807/1809 692/308/2778 Anemia Anesthesiology Animals Blood Blood pressure Catheters Contractility Ejection fraction Furosemide Heart Heart failure Heart rate Humanities and Social Sciences Intensive care Laboratories Morbidity multidisciplinary Ostomy Placebos Science Science (multidisciplinary) Stroke Transfusion Urine Ventricle
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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