The role of alternative splicing in cancer: From oncogenesis to drug resistance

Alternative splicing is a tightly regulated process whereby non-coding sequences of pre-mRNA are removed and protein-coding segments are assembled in diverse combinations, ultimately giving rise to proteins with distinct or even opposing functions. In the past decade, whole genome/transcriptome sequ...

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Veröffentlicht in:	Drug resistance updates Jg. 53; S. 100728
Hauptverfasser:	Sciarrillo, Rocco, Wojtuszkiewicz, Anna, Assaraf, Yehuda G., Jansen, Gerrit, Kaspers, Gertjan J.L., Giovannetti, Elisa, Cloos, Jacqueline
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Scotland Elsevier Ltd 01.12.2020
Schlagworte:	Alternative splicing Cancer Drug resistance Oncogenesis SF3B1 inhibition Splicing factor mutation Splicing modulation Alternative splicing SF3B1 inhibition Splicing modulation Splicing factor mutation Oncogenesis Drug resistance Cancer
ISSN:	1368-7646, 1532-2084, 1532-2084
Online-Zugang:	Volltext
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