Short-term pharmacologic RAGE inhibition differentially affects bone and skeletal muscle in middle-aged mice

Loss of bone and muscle mass are two major clinical complications among the growing list of chronic diseases that primarily affect elderly individuals. Persistent low-grade inflammation, one of the major drivers of aging, is also associated with both bone and muscle dysfunction in aging. Particularl...

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Veröffentlicht in:	Bone (New York, N.Y.) Jg. 124; S. 89 - 102
Hauptverfasser:	Davis, Hannah M., Essex, Alyson L., Valdez, Sinai, Deosthale, Padmini J., Aref, Mohammad W., Allen, Matthew R., Bonetto, Andrea, Plotkin, Lilian I.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Elsevier Inc 01.07.2019
Schlagworte:	Aging Inflammation Metabolism Osteoporosis RAGE Skeletal muscle Aging Osteoporosis Inflammation RAGE Metabolism Skeletal muscle
ISSN:	8756-3282, 1873-2763, 1873-2763
Online-Zugang:	Volltext
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