Dissection of Antibody Responses of Gam-COVID-Vac-Vaccinated Subjects Suggests Involvement of Epitopes Outside RBD in SARS-CoV-2 Neutralization

Millions of people have been vaccinated with Gam-COVID-Vac but fine specificities of induced antibodies have not been fully studied. Plasma from 12 naïve and 10 coronavirus disease 2019 (COVID-19) convalescent subjects was obtained before and after two immunizations with Gam-COVID-Vac. Antibody reac...

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Bibliographic Details
Published in:	International journal of molecular sciences Vol. 24; no. 6; p. 5104
Main Authors:	Byazrova, Maria, Gattinger, Pia, Astakhova, Ekaterina, Hofer, Gerhard, Khaitov, Musa, Filatov, Alexander, Valenta, Rudolf
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 07.03.2023 MDPI
Subjects:	Adenoviruses Allergens Antibodies Antibodies, Neutralizing Antibodies, Viral antibody Antibody Formation Antigenic determinants Antigens Coronaviruses COVID-19 COVID-19 vaccines epitope Epitopes Gam-COVID-Vac Health aspects Humans Immunoglobulin G Infections molecular interaction assay Omicron Pandemics Peptides Plasma Protein Subunits Proteins SARS-CoV-2 SARS-CoV-2 - metabolism Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Spike Glycoprotein, Coronavirus - metabolism Surgery Vaccination Viral antibodies Virus diseases virus-neutralization Austria Germany Russia COVID-19 SARS-CoV-2 antibody molecular interaction assay Gam-COVID-Vac virus-neutralization Omicron epitope
ISSN:	1422-0067, 1661-6596, 1422-0067
Online Access:	Get full text
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