A rigorous multi-laboratory study of known PDAC biomarkers identifies increased sensitivity and specificity over CA19-9 alone

A blood test that enables surveillance for early-stage pancreatic ductal adenocarcinoma (PDAC) is an urgent need. Independent laboratories have reported PDAC biomarkers that could improve biomarker performance over CA19-9 alone, but the performance of the previously reported biomarkers in combinatio...

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Bibliographic Details
Published in:	Cancer letters Vol. 604; p. 217245
Main Authors:	Haab, Brian, Qian, Lu, Staal, Ben, Jain, Maneesh, Fahrmann, Johannes, Worthington, Christine, Prosser, Denise, Velokokhatnaya, Liudmila, Lopez, Camden, Tang, Runlong, Hurd, Mark W., Natarajan, Gopalakrishnan, Kumar, Sushil, Smith, Lynette, Hanash, Sam, Batra, Surinder K., Maitra, Anirban, Lokshin, Anna, Huang, Ying, Brand, Randall E.
Format:	Journal Article
Language:	English
Published:	Ireland Elsevier B.V 01.11.2024
Subjects:	Aged Antigens, Tumor-Associated, Carbohydrate - blood Biomarkers Biomarkers, Tumor - blood CA 19–9 CA-19-9 Antigen - blood Carcinoma, Pancreatic Ductal - blood Carcinoma, Pancreatic Ductal - diagnosis Carcinoma, Pancreatic Ductal - pathology Case-Control Studies Early detection Female Humans Male Middle Aged Pancreatic adenocarcinoma Pancreatic Neoplasms - blood Pancreatic Neoplasms - diagnosis Pancreatic Neoplasms - pathology Panel Sensitivity and Specificity Pancreatic adenocarcinoma Biomarkers Panel CA 19–9 Early detection
ISSN:	0304-3835, 1872-7980, 1872-7980
Online Access:	Get full text
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