Establishment of a fluorescent reporter of RNA-polymerase II activity to identify dormant cells

Dormancy, a reversible quiescent cellular state characterized by greatly reduced metabolic activity, protects from genetic damage, prolongs survival and is crucial for tissue homeostasis and cellular response to injury or transplantation. Dormant cells have been characterized in many tissues, but th...

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Bibliographic Details
Published in:	Nature communications Vol. 12; no. 1; pp. 3318 - 16
Main Authors:	Freter, Rasmus, Falletta, Paola, Omrani, Omid, Rasa, Mahdi, Herbert, Katharine, Annunziata, Francesco, Minetti, Alberto, Krepelova, Anna, Adam, Lisa, Käppel, Sandra, Rüdiger, Tina, Wang, Zhao-Qi, Goding, Colin R., Neri, Francesco
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 03.06.2021 Nature Publishing Group Nature Portfolio
Subjects:	14 14/35 38 38/91 631/136/532/2118/2437 631/61/2320 631/80 631/80/641/2350 Chromosome aberrations Differentiation (biology) DNA-directed RNA polymerase Dormancy Elongation Epithelial cells Epithelium Fluorescence Homeostasis Humanities and Social Sciences Intestine multidisciplinary Phosphorylation Populations Ribonucleic acid RNA RNA polymerase RNA polymerase II Science Science (multidisciplinary) Small intestine Stem cells Transcription elongation Transplantation
ISSN:	2041-1723, 2041-1723
Online Access:	Get full text
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