Robust Image Population Based Stain Color Normalization: How Many Reference Slides Are Enough?

Histopathologic evaluation of Hematoxylin & Eosin (H&E) stained slides is essential for disease diagnosis, revealing tissue morphology, structure, and cellular composition. Variations in staining protocols and equipment result in images with color nonconformity. Although pathologists compens...

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Bibliographic Details
Published in:	IEEE open journal of engineering in medicine and biology Vol. 3; pp. 218 - 226
Main Authors:	Agraz, Jose L., Grenko, Caleb M., Chen, Andrew A., Viaene, Angela N., Nasrallah, MacLean D., Pati, Sarthak, Kurc, Tahsin, Saltz, Joel, Feldman, Michael D., Akbari, Hamed, Sharma, Parth, Shinohara, Russell T., Bakas, Spyridon
Format:	Journal Article
Language:	English
Published:	United States IEEE 01.01.2022 The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subjects:	Aggregates Cellular structure Color Computer applications Convergence Deconvolution Histograms Image color analysis Image processing Ivy GAP Medical imaging Pareto optimization Pareto principle rule Pathology Permutations Power law Principles Robustness (mathematics) Stain normalization bias problem Stains Strain Whole slide image Ivy GAP Pareto principle rule Stain normalization bias problem Whole slide image Power law
ISSN:	2644-1276, 2644-1276
Online Access:	Get full text
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