Functional characterization of bitter-taste receptors expressed in mammalian testis

Mammalian spermatogenesis and sperm maturation are susceptible to the effects of internal and external factors. However, how male germ cells interact with and respond to these elements including those potentially toxic substances is poorly understood. Here, we show that many bitter-taste receptors (...

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Vydáno v:	Molecular human reproduction Ročník 19; číslo 1; s. 17
Hlavní autoři:	Xu, Jiang, Cao, Jie, Iguchi, Naoko, Riethmacher, Dieter, Huang, Liquan
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	England 01.01.2013
Témata:	Animals Benzyl Alcohols - pharmacology Caffeine - pharmacology Calcium - metabolism Gene Expression - drug effects Glucosides - pharmacology Heterotrimeric GTP-Binding Proteins - deficiency Heterotrimeric GTP-Binding Proteins - genetics Humans Male Meiosis - drug effects Meiosis - genetics Mice Phenylthiourea - pharmacology Probenecid - pharmacology Protein Isoforms - genetics Protein Isoforms - metabolism Protein Subunits - deficiency Protein Subunits - genetics Receptors, G-Protein-Coupled - genetics Receptors, G-Protein-Coupled - metabolism RNA, Messenger - biosynthesis RNA, Messenger - genetics Seminiferous Tubules - anatomy & histology Seminiferous Tubules - drug effects Seminiferous Tubules - metabolism Signal Transduction - drug effects Spermatids - drug effects Spermatids - physiology Spermatogenesis - physiology Taste - physiology
ISSN:	1460-2407, 1460-2407
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