Recombination between non-structural and structural genes as a mechanism of selection in lagoviruses: The evolutionary dead-end of an RHDV2 isolated from European hare

•RHDV2_Bg12 originated in a hare through recombination at the RdP-VP60 junction.•Structural genes come from RHDV2, the non-structural ones from a new hare lagovirus.•Rabbits orally inoculated with RHDV2_Bg12 neither developed RHD nor seroconverted.•RHDV2_Bg12 has no longer been identified despite ac...

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Bibliographic Details
Published in:	Virus research Vol. 339; p. 199257
Main Authors:	Cavadini, Patrizia, Trogu, Tiziana, Velarde, Roser, Lavazza, Antonio, Capucci, Lorenzo
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 02.01.2024 Elsevier
Subjects:	Animal experiments Animals Australia Biological Evolution Caliciviridae Infections - epidemiology Caliciviridae Infections - veterinary European brown hare syndrome virus family genes genotype genus Hares Hemorrhagic Disease Virus, Rabbit - genetics hepatitis host specificity Italy Lagovirus Lepus europaeus monitoring Phylogeny Rabbit hemorrhagic disease virus Rabbits Recombination Recombination, Genetic RHDV2 species Vesivirus Virus selection viruses Australia Italy Virus selection Recombination Animal experiments Lagovirus RHDV2
ISSN:	0168-1702, 1872-7492, 1872-7492
Online Access:	Get full text
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