Recombination between non-structural and structural genes as a mechanism of selection in lagoviruses: The evolutionary dead-end of an RHDV2 isolated from European hare
•RHDV2_Bg12 originated in a hare through recombination at the RdP-VP60 junction.•Structural genes come from RHDV2, the non-structural ones from a new hare lagovirus.•Rabbits orally inoculated with RHDV2_Bg12 neither developed RHD nor seroconverted.•RHDV2_Bg12 has no longer been identified despite ac...
Gespeichert in:
| Veröffentlicht in: | Virus research Jg. 339; S. 199257 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Journal Article |
| Sprache: | Englisch |
| Veröffentlicht: |
Netherlands
Elsevier B.V
02.01.2024
Elsevier |
| Schlagworte: | |
| ISSN: | 0168-1702, 1872-7492, 1872-7492 |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Abstract | •RHDV2_Bg12 originated in a hare through recombination at the RdP-VP60 junction.•Structural genes come from RHDV2, the non-structural ones from a new hare lagovirus.•Rabbits orally inoculated with RHDV2_Bg12 neither developed RHD nor seroconverted.•RHDV2_Bg12 has no longer been identified despite active surveillance on lagomorphs.
The genus Lagovirus, belonging to the family Caliciviridae, emerged around the 1980s. It includes highly pathogenic species, rabbit hemorrhagic disease virus (RHDV/GI.1) and European brown hare syndrome virus (EBHSV/GII.1), which cause fatal hepatitis, and nonpathogenic viruses with enteric tropism, rabbit calicivirus (RCV/GI.3,4) and hare calicivirus (HaCV/GII.2). Lagoviruses have evolved along two independent genetic lineages: GI (RHDV and RCV) in rabbits and GII (EBHSV and HaCV) in hares. To be emphasized is that genomes of lagoviruses, like other caliciviruses, are highly conserved at RdRp-VP60 junctions, favoring intergenotypic recombination events at this point. The recombination between an RCV (genotype GI.3), donor of non-structural (NS) genes, and an unknown virus, donor of structural (S) genes, likely led to the emergence of a new lagovirus in the European rabbit, called RHDV type 2 (GI.2), identified in Europe in 2010. New RHDV2 intergenotypic recombinants isolated in rabbits in Europe and Australia originated from similar events between RHDV2 (GI.2) and RHDV (GI.1) or RCV (GI.3,4). RHDV2 (GI.2) rapidly spread worldwide, replacing RHDV and showing several lagomorph species as secondary hosts. The recombination events in RHDV2 viruses have led to a number of viruses with very different combinations of NS and S genes. Recombinant RHDV2 with NS genes from hare lineage (GII) was recently identified in the European hare. This study investigated the first RHDV2 (GI.2) identified in Italy in European hare (RHDV2_Bg12), demonstrating that it was a new virus that originated from the recombination between RHDV2, as an S-gene donor and a hare lagovirus, not yet identified but presumably nonpathogenic, as an NS gene donor. When rabbits were inoculated with RHDV2_Bg12, neither deaths nor seroconversions were recorded, demonstrating that RHDV2_Bg12 cannot infect the rabbit. Furthermore, despite intensive and continuous field surveillance, RHDV2_Bg12 has never again been identified in either hares or rabbits in Italy or elsewhere. This result showed that the host specificity of lagoviruses can depend not only on S genes, as expected until today, but potentially also on some species-specific NS gene sequences. Therefore, because RHDV2 (GI.2) infects several lagomorphs, which in turn probably harbor several specific nonpathogenic lagoviruses, the possibility of new speciation, especially in those other than rabbits, is real. RHDV2 Bg_12 demonstrated this, although the attempt apparently failed. |
|---|---|
| AbstractList | •RHDV2_Bg12 originated in a hare through recombination at the RdP-VP60 junction.•Structural genes come from RHDV2, the non-structural ones from a new hare lagovirus.•Rabbits orally inoculated with RHDV2_Bg12 neither developed RHD nor seroconverted.•RHDV2_Bg12 has no longer been identified despite active surveillance on lagomorphs.
The genus Lagovirus, belonging to the family Caliciviridae, emerged around the 1980s. It includes highly pathogenic species, rabbit hemorrhagic disease virus (RHDV/GI.1) and European brown hare syndrome virus (EBHSV/GII.1), which cause fatal hepatitis, and nonpathogenic viruses with enteric tropism, rabbit calicivirus (RCV/GI.3,4) and hare calicivirus (HaCV/GII.2). Lagoviruses have evolved along two independent genetic lineages: GI (RHDV and RCV) in rabbits and GII (EBHSV and HaCV) in hares. To be emphasized is that genomes of lagoviruses, like other caliciviruses, are highly conserved at RdRp-VP60 junctions, favoring intergenotypic recombination events at this point. The recombination between an RCV (genotype GI.3), donor of non-structural (NS) genes, and an unknown virus, donor of structural (S) genes, likely led to the emergence of a new lagovirus in the European rabbit, called RHDV type 2 (GI.2), identified in Europe in 2010. New RHDV2 intergenotypic recombinants isolated in rabbits in Europe and Australia originated from similar events between RHDV2 (GI.2) and RHDV (GI.1) or RCV (GI.3,4). RHDV2 (GI.2) rapidly spread worldwide, replacing RHDV and showing several lagomorph species as secondary hosts. The recombination events in RHDV2 viruses have led to a number of viruses with very different combinations of NS and S genes. Recombinant RHDV2 with NS genes from hare lineage (GII) was recently identified in the European hare. This study investigated the first RHDV2 (GI.2) identified in Italy in European hare (RHDV2_Bg12), demonstrating that it was a new virus that originated from the recombination between RHDV2, as an S-gene donor and a hare lagovirus, not yet identified but presumably nonpathogenic, as an NS gene donor. When rabbits were inoculated with RHDV2_Bg12, neither deaths nor seroconversions were recorded, demonstrating that RHDV2_Bg12 cannot infect the rabbit. Furthermore, despite intensive and continuous field surveillance, RHDV2_Bg12 has never again been identified in either hares or rabbits in Italy or elsewhere. This result showed that the host specificity of lagoviruses can depend not only on S genes, as expected until today, but potentially also on some species-specific NS gene sequences. Therefore, because RHDV2 (GI.2) infects several lagomorphs, which in turn probably harbor several specific nonpathogenic lagoviruses, the possibility of new speciation, especially in those other than rabbits, is real. RHDV2 Bg_12 demonstrated this, although the attempt apparently failed. The genus Lagovirus, belonging to the family Caliciviridae, emerged around the 1980s. It includes highly pathogenic species, rabbit hemorrhagic disease virus (RHDV/GI.1) and European brown hare syndrome virus (EBHSV/GII.1), which cause fatal hepatitis, and nonpathogenic viruses with enteric tropism, rabbit calicivirus (RCV/GI.3,4) and hare calicivirus (HaCV/GII.2). Lagoviruses have evolved along two independent genetic lineages: GI (RHDV and RCV) in rabbits and GII (EBHSV and HaCV) in hares. To be emphasized is that genomes of lagoviruses, like other caliciviruses, are highly conserved at RdRp-VP60 junctions, favoring intergenotypic recombination events at this point. The recombination between an RCV (genotype GI.3), donor of non-structural (NS) genes, and an unknown virus, donor of structural (S) genes, likely led to the emergence of a new lagovirus in the European rabbit, called RHDV type 2 (GI.2), identified in Europe in 2010. New RHDV2 intergenotypic recombinants isolated in rabbits in Europe and Australia originated from similar events between RHDV2 (GI.2) and RHDV (GI.1) or RCV (GI.3,4). RHDV2 (GI.2) rapidly spread worldwide, replacing RHDV and showing several lagomorph species as secondary hosts. The recombination events in RHDV2 viruses have led to a number of viruses with very different combinations of NS and S genes. Recombinant RHDV2 with NS genes from hare lineage (GII) was recently identified in the European hare. This study investigated the first RHDV2 (GI.2) identified in Italy in European hare (RHDV2_Bg12), demonstrating that it was a new virus that originated from the recombination between RHDV2, as an S-gene donor and a hare lagovirus, not yet identified but presumably nonpathogenic, as an NS gene donor. When rabbits were inoculated with RHDV2_Bg12, neither deaths nor seroconversions were recorded, demonstrating that RHDV2_Bg12 cannot infect the rabbit. Furthermore, despite intensive and continuous field surveillance, RHDV2_Bg12 has never again been identified in either hares or rabbits in Italy or elsewhere. This result showed that the host specificity of lagoviruses can depend not only on S genes, as expected until today, but potentially also on some species-specific NS gene sequences. Therefore, because RHDV2 (GI.2) infects several lagomorphs, which in turn probably harbor several specific nonpathogenic lagoviruses, the possibility of new speciation, especially in those other than rabbits, is real. RHDV2 Bg_12 demonstrated this, although the attempt apparently failed.The genus Lagovirus, belonging to the family Caliciviridae, emerged around the 1980s. It includes highly pathogenic species, rabbit hemorrhagic disease virus (RHDV/GI.1) and European brown hare syndrome virus (EBHSV/GII.1), which cause fatal hepatitis, and nonpathogenic viruses with enteric tropism, rabbit calicivirus (RCV/GI.3,4) and hare calicivirus (HaCV/GII.2). Lagoviruses have evolved along two independent genetic lineages: GI (RHDV and RCV) in rabbits and GII (EBHSV and HaCV) in hares. To be emphasized is that genomes of lagoviruses, like other caliciviruses, are highly conserved at RdRp-VP60 junctions, favoring intergenotypic recombination events at this point. The recombination between an RCV (genotype GI.3), donor of non-structural (NS) genes, and an unknown virus, donor of structural (S) genes, likely led to the emergence of a new lagovirus in the European rabbit, called RHDV type 2 (GI.2), identified in Europe in 2010. New RHDV2 intergenotypic recombinants isolated in rabbits in Europe and Australia originated from similar events between RHDV2 (GI.2) and RHDV (GI.1) or RCV (GI.3,4). RHDV2 (GI.2) rapidly spread worldwide, replacing RHDV and showing several lagomorph species as secondary hosts. The recombination events in RHDV2 viruses have led to a number of viruses with very different combinations of NS and S genes. Recombinant RHDV2 with NS genes from hare lineage (GII) was recently identified in the European hare. This study investigated the first RHDV2 (GI.2) identified in Italy in European hare (RHDV2_Bg12), demonstrating that it was a new virus that originated from the recombination between RHDV2, as an S-gene donor and a hare lagovirus, not yet identified but presumably nonpathogenic, as an NS gene donor. When rabbits were inoculated with RHDV2_Bg12, neither deaths nor seroconversions were recorded, demonstrating that RHDV2_Bg12 cannot infect the rabbit. Furthermore, despite intensive and continuous field surveillance, RHDV2_Bg12 has never again been identified in either hares or rabbits in Italy or elsewhere. This result showed that the host specificity of lagoviruses can depend not only on S genes, as expected until today, but potentially also on some species-specific NS gene sequences. Therefore, because RHDV2 (GI.2) infects several lagomorphs, which in turn probably harbor several specific nonpathogenic lagoviruses, the possibility of new speciation, especially in those other than rabbits, is real. RHDV2 Bg_12 demonstrated this, although the attempt apparently failed. The genus Lagovirus, belonging to the family Caliciviridae, emerged around the 1980s. It includes highly pathogenic species, rabbit hemorrhagic disease virus (RHDV/GI.1) and European brown hare syndrome virus (EBHSV/GII.1), which cause fatal hepatitis, and nonpathogenic viruses with enteric tropism, rabbit calicivirus (RCV/GI.3,4) and hare calicivirus (HaCV/GII.2). Lagoviruses have evolved along two independent genetic lineages: GI (RHDV and RCV) in rabbits and GII (EBHSV and HaCV) in hares. To be emphasized is that genomes of lagoviruses, like other caliciviruses, are highly conserved at RdRp-VP60 junctions, favoring intergenotypic recombination events at this point. The recombination between an RCV (genotype GI.3), donor of non-structural (NS) genes, and an unknown virus, donor of structural (S) genes, likely led to the emergence of a new lagovirus in the European rabbit, called RHDV type 2 (GI.2), identified in Europe in 2010. New RHDV2 intergenotypic recombinants isolated in rabbits in Europe and Australia originated from similar events between RHDV2 (GI.2) and RHDV (GI.1) or RCV (GI.3,4). RHDV2 (GI.2) rapidly spread worldwide, replacing RHDV and showing several lagomorph species as secondary hosts. The recombination events in RHDV2 viruses have led to a number of viruses with very different combinations of NS and S genes. Recombinant RHDV2 with NS genes from hare lineage (GII) was recently identified in the European hare. This study investigated the first RHDV2 (GI.2) identified in Italy in European hare (RHDV2_Bg12), demonstrating that it was a new virus that originated from the recombination between RHDV2, as an S-gene donor and a hare lagovirus, not yet identified but presumably nonpathogenic, as an NS gene donor. When rabbits were inoculated with RHDV2_Bg12, neither deaths nor seroconversions were recorded, demonstrating that RHDV2_Bg12 cannot infect the rabbit. Furthermore, despite intensive and continuous field surveillance, RHDV2_Bg12 has never again been identified in either hares or rabbits in Italy or elsewhere. This result showed that the host specificity of lagoviruses can depend not only on S genes, as expected until today, but potentially also on some species-specific NS gene sequences. Therefore, because RHDV2 (GI.2) infects several lagomorphs, which in turn probably harbor several specific nonpathogenic lagoviruses, the possibility of new speciation, especially in those other than rabbits, is real. RHDV2 Bg_12 demonstrated this, although the attempt apparently failed. |
| ArticleNumber | 199257 |
| Author | Velarde, Roser Cavadini, Patrizia Lavazza, Antonio Capucci, Lorenzo Trogu, Tiziana |
| Author_xml | – sequence: 1 givenname: Patrizia surname: Cavadini fullname: Cavadini, Patrizia organization: Istituto Zooprofilattico Sperimentale della Lombardia ed Emilia Romagna Via Bianchi 9, 25124 Brescia, Italy – sequence: 2 givenname: Tiziana surname: Trogu fullname: Trogu, Tiziana organization: Istituto Zooprofilattico Sperimentale della Lombardia ed Emilia Romagna Via Bianchi 9, 25124 Brescia, Italy – sequence: 3 givenname: Roser surname: Velarde fullname: Velarde, Roser organization: Wildlife Ecology & Health group (WEH) and Servei d'Ecopatologia de Fauna Salvatge (SEFaS), Departament de Medicina i Cirurgia Animals, Universitat Autònoma de Barcelona, Bellaterra, Spain – sequence: 4 givenname: Antonio surname: Lavazza fullname: Lavazza, Antonio email: antonio.lavazza@izsler.it organization: Istituto Zooprofilattico Sperimentale della Lombardia ed Emilia Romagna Via Bianchi 9, 25124 Brescia, Italy – sequence: 5 givenname: Lorenzo orcidid: 0000-0002-1830-3929 surname: Capucci fullname: Capucci, Lorenzo organization: Istituto Zooprofilattico Sperimentale della Lombardia ed Emilia Romagna Via Bianchi 9, 25124 Brescia, Italy |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/38347757$$D View this record in MEDLINE/PubMed |
| BookMark | eNqFkt9qFDEUxgep2G31FUouvZk1yfxJRrxQarWFglCqt-FMcmY3y0yyJjNbfCJf0-xOV8SbhUBI8n2_c8j5LrIz5x1m2RWjS0ZZ_W6z3NkwxYBxySkvlqxpeCVeZAsmBc9F2fCzbJGEMmeC8vPsIsYNpbQuRP0qOy9kUQpRiUX2-wG1H1rrYLTekRbHJ0RHUrU8jmHS4xSgJ-AM-ee4QoeRQFpkQL0GZ-NAfEci9qgPHOtIDyt_6BHje_K4RoI730_7Vwi_iEEwOSZssoEjD7eff3Bio-9hREO64AdyMwW_xfS4hoCvs5cd9BHfPO-X2fcvN4_Xt_n9t69315_uc12xasxRam5qA0YYwSQIoBUHLTpmBJYVBS5KwxrDjeyAa9kaLosKGW9MI1EKWVxmdzPXeNiobbBD6lZ5sOpw4cNKQRit7lE1qKHVHYApaMnbTiYYFKl2yzXTpU6stzNrG_zPCeOoBhs19j049FNUyUaLqq4bflLKG15TSXlTJ-nVs3RqBzR_ezzONAk-zAIdfEwJ6ZS242G8YwDbK0bVPkJqo44RUvsIqTlCyV7_Zz9WOGn8OBsxzWdnMaioLTqNxoYUi_SB9hTiDzsB6TQ |
| CitedBy_id | crossref_primary_10_1038_s41598_024_79670_y crossref_primary_10_1155_tbed_1129135 crossref_primary_10_1016_j_vetmic_2025_110478 crossref_primary_10_3390_v16060927 crossref_primary_10_3390_v17050710 crossref_primary_10_3390_v16030437 |
| Cites_doi | 10.1128/jvi.64.7.3331-3336.1990 10.1136/vr.104132 10.1038/s41598-017-13902-2 10.1128/JVI.01759-17 10.1371/journal.ppat.1003132 10.1093/ve/veaa080 10.1136/vr.104034 10.1093/molbev/msy096 10.1186/1297-9716-44-96 10.1007/s00705-016-3082-6 10.1016/0042-6822(91)90436-F 10.1099/jgv.0.000840 10.20506/rst.21.2.1337 10.1099/vir.0.81537-0 10.1186/1297-9716-43-12 10.7589/0090-3558-34.2.221 10.1128/jvi.64.8.4013-4015.1990 10.1111/tbed.13706 10.1016/j.virol.2008.11.004 10.1099/vir.0.83321-0 10.1111/tbed.12779 10.1177/10406387211006353 10.1128/JVI.73.1.152-160.1999 10.1017/S0950268899003994 10.1016/j.virol.2010.12.001 10.3201/eid2112.151210 10.1128/JVI.01937-15 10.3201/eid1812.120341 10.1093/ve/vev003 10.1111/tbed.14264 10.3201/eid2401.170412 10.1099/jgv.0.001332 10.1111/tbed.14315 10.3201/eid1107.041273 10.1177/10406387211022466 10.1128/mra.01224-18 10.1099/vir.0.000070 10.1016/0168-1702(96)01285-3 10.20506/rst.10.2.549 10.1093/ve/veab080 10.1111/tbed.12830 10.1086/315591 10.1016/0042-6822(91)90437-G 10.3201/eid1512.090839 10.20506/rst.10.2.560 10.1016/j.rvsc.2014.10.008 10.1186/1743-422X-4-96 10.1111/tbed.12562 10.1186/1297-9716-44-81 10.1016/0168-1702(95)00033-M 10.20506/rst.10.2.561 10.1136/vr.d697 10.3390/genes11080910 10.1093/ve/vez005 10.1186/s13567-017-0473-y 10.1038/s41598-020-71303-4 10.1128/jvi.70.12.8614-8623.1996 10.1186/s13567-015-0149-4 10.20506/rst.10.2.555 |
| ContentType | Journal Article |
| Copyright | 2023 Copyright © 2023. Published by Elsevier B.V. |
| Copyright_xml | – notice: 2023 – notice: Copyright © 2023. Published by Elsevier B.V. |
| DBID | 6I. AAFTH AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 7S9 L.6 DOA |
| DOI | 10.1016/j.virusres.2023.199257 |
| DatabaseName | ScienceDirect Open Access Titles Elsevier:ScienceDirect:Open Access CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic AGRICOLA AGRICOLA - Academic DOAJ Directory of Open Access Journals |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic AGRICOLA AGRICOLA - Academic |
| DatabaseTitleList | MEDLINE - Academic AGRICOLA MEDLINE |
| Database_xml | – sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Biology |
| EISSN | 1872-7492 |
| ExternalDocumentID | oai_doaj_org_article_9ecabcfaad3042bf8d28a3dadb2c1c4c 38347757 10_1016_j_virusres_2023_199257 S0168170223002198 |
| Genre | Journal Article |
| GeographicLocations | Australia Italy |
| GeographicLocations_xml | – name: Australia – name: Italy |
| GroupedDBID | --- --K --M .~1 0R~ 0SF 123 1B1 1RT 1~. 1~5 4.4 457 4G. 5RE 5VS 6I. 7-5 71M 8P~ 9JM AAAJQ AABNK AACTN AAEDT AAEDW AAFTH AAIAV AAIKJ AAKOC AALRI AAOAW AAQFI AARKO AAXUO ABBQC ABFRF ABJNI ABLVK ABMAC ABMZM ABYKQ ACDAQ ACGFO ACGFS ACIUM ACRLP ADBBV ADEZE AEBSH AEFWE AEKER AENEX AFKWA AFTJW AFXIZ AGEKW AGHFR AGUBO AGYEJ AIEXJ AIKHN AITUG AJOXV AJRQY AKRWK ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ ANZVX AXJTR BKOJK BLXMC BNPGV CJTIS CNWQP CS3 DU5 EBS EFJIC EO8 EO9 EP2 EP3 F5P FDB FIRID FNPLU FYGXN G-Q GBLVA GROUPED_DOAJ IH2 IHE J1W KOM LUGTX M41 MO0 N9A O-L O9- OAUVE OZT P-8 P-9 P2P PC. Q38 RIG ROL RPM RPZ SCC SDF SDG SDP SES SEW SIN SPCBC SSH SSI SSZ T5K WH7 ~G- .GJ 29Q 53G 9DU AAHBH AAQXK AATTM AAXKI AAYWO AAYXX ABFNM ABWVN ABXDB ACIEU ACLOT ACRPL ACVFH ADCNI ADMUD ADNMO ADVLN AEIPS AEUPX AFJKZ AFPUW AGQPQ AHHHB AIGII AIIUN AKBMS AKYEP ANKPU APXCP ASPBG AVWKF AZFZN CITATION EFKBS EFLBG EJD FEDTE FGOYB G-2 HMG HVGLF HZ~ R2- WUQ ZGI ~HD CGR CUY CVF ECM EIF NPM 7X8 7S9 L.6 |
| ID | FETCH-LOGICAL-c515t-e8c2d6dad7d718a7a052ac7f1d7e450a274d19d2d8fa2c8bd2835e129d98e8783 |
| IEDL.DBID | DOA |
| ISICitedReferencesCount | 7 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=001166945400001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 0168-1702 1872-7492 |
| IngestDate | Fri Oct 03 12:37:11 EDT 2025 Thu Oct 02 22:49:41 EDT 2025 Thu Oct 02 10:16:34 EDT 2025 Mon Nov 10 01:25:23 EST 2025 Tue Nov 18 20:53:15 EST 2025 Sat Nov 29 07:24:27 EST 2025 Sat May 04 15:43:12 EDT 2024 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Keywords | Virus selection Recombination Animal experiments Lagovirus RHDV2 |
| Language | English |
| License | This is an open access article under the CC BY-NC license. Copyright © 2023. Published by Elsevier B.V. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c515t-e8c2d6dad7d718a7a052ac7f1d7e450a274d19d2d8fa2c8bd2835e129d98e8783 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ORCID | 0000-0002-1830-3929 |
| OpenAccessLink | https://doaj.org/article/9ecabcfaad3042bf8d28a3dadb2c1c4c |
| PMID | 38347757 |
| PQID | 2926080296 |
| PQPubID | 23479 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_9ecabcfaad3042bf8d28a3dadb2c1c4c proquest_miscellaneous_3040356692 proquest_miscellaneous_2926080296 pubmed_primary_38347757 crossref_citationtrail_10_1016_j_virusres_2023_199257 crossref_primary_10_1016_j_virusres_2023_199257 elsevier_sciencedirect_doi_10_1016_j_virusres_2023_199257 |
| PublicationCentury | 2000 |
| PublicationDate | 2024-01-02 |
| PublicationDateYYYYMMDD | 2024-01-02 |
| PublicationDate_xml | – month: 01 year: 2024 text: 2024-01-02 day: 02 |
| PublicationDecade | 2020 |
| PublicationPlace | Netherlands |
| PublicationPlace_xml | – name: Netherlands |
| PublicationTitle | Virus research |
| PublicationTitleAlternate | Virus Res |
| PublicationYear | 2024 |
| Publisher | Elsevier B.V Elsevier |
| Publisher_xml | – name: Elsevier B.V – name: Elsevier |
| References | Capucci, Scicluna, Lavazza (bib0015) 1991; 10 Dalton, Nicieza, Balseiro, Muguerza, Rosell, Casais (bib0020) 2012; 18 Lavazza, Cavadini, Barbieri, Tizzani, Pinheiro, Abrantes (bib0031) 2015; 46 Liu (bib0039) 1984; 16 Lavazza, Scicluna, Capucci (bib0033) 1996; 43 Abrantes, Lopes, Lemaitre, Ahola, Banihashem, Droillard (bib0002) 2020; 11 Mahar, Jenckel, Huang, Smertina, Holmes, Strive (bib0045) 2021; 7 Cavadini, Molinari, Merzoni, Vismarra, Posautz, Gil, Chiari, Giannini, Capucci, Lavazza (bib0016) 2021; 68 Vinje, Estes, Esteves, Green, Katayama, Knowles (bib0062) 2019; 100 Abrantes, van der Loo, Le Pendu, Esteves (bib0003) 2012; 43 Mahar, Hall, Shi, Mourant, Huang, Strive (bib0044) 2019; 5 Cooke (bib0018) 2002; 21 Capucci, Frigoli, Ronshold, Lavazza, Brocchi, Rossi (bib0013) 1995; 37 Hall, Mahar, Haboury, Stevens, Holmes, Strive (bib0026) 2015; 21 Szillat, Hoper, Beer, Konig (bib0059) 2020; 6 Coyne, Reed, Porter, Dawson, Gaskell, Radford (bib0019) 2006; 87 Droillard, Lemaitre, Chatel, Guitton, Marchandeau, Eterradossi, Le Gall-Reculé (bib0021) 2018; 7 Le Gall-Recule, Lavazza, Marchandeau, Bertagnoli, Zwingelstein, Cavadini (bib0034) 2013; 44 Bull, Hansman, Clancy, Tanaka, Rawlinson, White (bib0008) 2005; 11 Kumar, Stecher, Li, Knyaz, Tamura (bib0030) 2018; 35 Camarda, Pugliese, Cavadini, Circella, Capucci, Caroli (bib0010) 2014; 97 Lole, Bollinger, Paranjape, Gadkari, Kulkarni, Novak, Ingersoll, Sheppard, Ray (bib0040) 1999; 73 Meyers, Wirblich, Thiel (bib0050) 1991; 184 Hall, Mahar, Read, Mourant, Piper, Huang (bib0027) 2018; 65 Cooke, Robinson, Merchant, Nardin, Capucci (bib0017) 2000; 124 Lopes, Breiman, Lora, Le Moullac-Vaidye, Galanina, Nystrom (bib0041) 2018; 92 Ohlinger, Haas, Meyers, Weiland, Thiel (bib0054) 1990; 64 Eden, Read, Duckworth, Strive, Holmes (bib0022) 2015; 89 Meyers, Wirblich, Thiel (bib0051) 1991; 184 Silverio, Lopes, Melo-Ferreira, Magalhaes, Monterroso, Serronha (bib0057) 2018; 65 Martin, Murrell, Golden, Khoosal, Muhire (bib0048) 2015; 1 Lopes, Silverio, Magalhaes, Areal, Alves, Esteves (bib0043) 2017; 7 Mahar, Read, Gu, Urakova, Mourant, Piper (bib0046) 2018; 24 Lavazza, Pascucci, Gelmetti (bib0032) 1990; 126 Le Pendu, Abrantes, Bertagnoli, Guitton, Le Gall-Recule, Lopes (bib0038) 2017; 98 Capucci, Fusi, Lavazza, Pacciarini, Rossi (bib0014) 1996; 70 Gavier-Widen, Morner (bib0023) 1991; 10 Strive, Wright, Robinson (bib0058) 2009; 384 Velarde, Abrantes, Lopes, Estruch, Corte-Real, Esteves (bib0060) 2021; 68 Hu, Wang, Fan, Song, Abrantes, Zuo (bib0029) 2017; 162 Le Gall-Recule, Lemaitre, Bertagnoli, Hubert, Top, Decors (bib0035) 2017; 48 Granzow, Weiland, Strebelow, Liu, Schirrmeier (bib0024) 1996; 41 Bergin, Wise, Bolin, Mullaney, Kiupel, Maes (bib0007) 2009; 15 Le Gall-Recule, Zwingelstein, Boucher, Le Normand, Plassiart, Portejoie (bib0036) 2011; 168 Mutze, Cooke, Alexander (bib0053) 1998; 34 Williams, Edmonds, Kerr, Broughton-Neiswanger, Snekvik (bib0064) 2021; 33 Hall, Peacock, Kovaliski, Mahar, Mourant, Piper, Strive (bib0028) 2017; 180 Asin, Nyaoke, Moore, Gonzalez-Astudillo, Clifford, Lantz (bib0004) 2021; 33 Morisse, Le Gall, Boilletot (bib0052) 1991; 10 (bib0065) 2023 Asin, Rejmanek, Clifford, Mikolon, Henderson, Nyaoke (bib0005) 2022; 69 Marcato, Benazzi, Vecchi, Galeotti, Della Salda, Sarli (bib0047) 1991; 10 Bull, Tanaka, White (bib0009) 2007; 88 Capucci, Cavadini, Schiavitto, Lombardi, Lavazza (bib0012) 2017; 180 Velarde, Cavadini, Neimanis, Cabezon, Chiari, Gaffuri (bib0061) 2017; 64 Capucci, Cavadini, Lavazza (bib0011) 2017 Puggioni, Cavadini, Maestrale, Scivoli, Botti, Ligios (bib0056) 2013; 44 Abrantes, Droillard, Lopes, Lemaitre, Lucas, Blanchard (bib0001) 2020; 10 McIntosh, Behan, Mohamed, Lu, Moran, Burrage (bib0049) 2007; 4 Lopes, Dalton, Magalhaes, Parra, Esteves, Holmes (bib0042) 2015; 96 Le Gall-Recule, Zwingelstein, Fages, Bertagnoli, Gelfi, Aubineau (bib0037) 2011; 410 Parra, Prieto (bib0055) 1990; 64 Green, Ando, Balayan, Berke, Clarke, Estes (bib0025) 2000; 181 Ben Chehida, Lopes, Corte-Real, Sghaier, Aouini, Messadi (bib0006) 2021; 10 Wang, Xu, Liu, Gao, Liu, Zhai (bib0063) 2013; 9 Dalton (10.1016/j.virusres.2023.199257_bib0020) 2012; 18 Morisse (10.1016/j.virusres.2023.199257_bib0052) 1991; 10 Puggioni (10.1016/j.virusres.2023.199257_bib0056) 2013; 44 Abrantes (10.1016/j.virusres.2023.199257_bib0001) 2020; 10 Meyers (10.1016/j.virusres.2023.199257_bib0050) 1991; 184 Mahar (10.1016/j.virusres.2023.199257_bib0045) 2021; 7 Asin (10.1016/j.virusres.2023.199257_bib0005) 2022; 69 Cooke (10.1016/j.virusres.2023.199257_bib0018) 2002; 21 Lole (10.1016/j.virusres.2023.199257_bib0040) 1999; 73 Lopes (10.1016/j.virusres.2023.199257_bib0043) 2017; 7 Ben Chehida (10.1016/j.virusres.2023.199257_bib0006) 2021; 10 Capucci (10.1016/j.virusres.2023.199257_bib0012) 2017; 180 Mahar (10.1016/j.virusres.2023.199257_bib0046) 2018; 24 Velarde (10.1016/j.virusres.2023.199257_bib0061) 2017; 64 Silverio (10.1016/j.virusres.2023.199257_bib0057) 2018; 65 Gavier-Widen (10.1016/j.virusres.2023.199257_bib0023) 1991; 10 Hall (10.1016/j.virusres.2023.199257_bib0026) 2015; 21 Bergin (10.1016/j.virusres.2023.199257_bib0007) 2009; 15 Lavazza (10.1016/j.virusres.2023.199257_bib0032) 1990; 126 Lopes (10.1016/j.virusres.2023.199257_bib0041) 2018; 92 Kumar (10.1016/j.virusres.2023.199257_bib0030) 2018; 35 Ohlinger (10.1016/j.virusres.2023.199257_bib0054) 1990; 64 Lopes (10.1016/j.virusres.2023.199257_bib0042) 2015; 96 Hall (10.1016/j.virusres.2023.199257_bib0028) 2017; 180 Le Pendu (10.1016/j.virusres.2023.199257_bib0038) 2017; 98 Capucci (10.1016/j.virusres.2023.199257_bib0013) 1995; 37 Green (10.1016/j.virusres.2023.199257_bib0025) 2000; 181 Abrantes (10.1016/j.virusres.2023.199257_bib0002) 2020; 11 Lavazza (10.1016/j.virusres.2023.199257_bib0031) 2015; 46 Granzow (10.1016/j.virusres.2023.199257_bib0024) 1996; 41 Bull (10.1016/j.virusres.2023.199257_bib0009) 2007; 88 Lavazza (10.1016/j.virusres.2023.199257_bib0033) 1996; 43 Le Gall-Recule (10.1016/j.virusres.2023.199257_bib0034) 2013; 44 Le Gall-Recule (10.1016/j.virusres.2023.199257_bib0036) 2011; 168 Coyne (10.1016/j.virusres.2023.199257_bib0019) 2006; 87 Szillat (10.1016/j.virusres.2023.199257_bib0059) 2020; 6 (10.1016/j.virusres.2023.199257_bib0065) 2023 Mutze (10.1016/j.virusres.2023.199257_bib0053) 1998; 34 Asin (10.1016/j.virusres.2023.199257_bib0004) 2021; 33 Liu (10.1016/j.virusres.2023.199257_bib0039) 1984; 16 Hu (10.1016/j.virusres.2023.199257_bib0029) 2017; 162 Vinje (10.1016/j.virusres.2023.199257_bib0062) 2019; 100 Camarda (10.1016/j.virusres.2023.199257_bib0010) 2014; 97 Mahar (10.1016/j.virusres.2023.199257_bib0044) 2019; 5 Meyers (10.1016/j.virusres.2023.199257_bib0051) 1991; 184 Cooke (10.1016/j.virusres.2023.199257_bib0017) 2000; 124 Bull (10.1016/j.virusres.2023.199257_bib0008) 2005; 11 Eden (10.1016/j.virusres.2023.199257_bib0022) 2015; 89 Williams (10.1016/j.virusres.2023.199257_bib0064) 2021; 33 Capucci (10.1016/j.virusres.2023.199257_bib0015) 1991; 10 Le Gall-Recule (10.1016/j.virusres.2023.199257_bib0035) 2017; 48 Hall (10.1016/j.virusres.2023.199257_bib0027) 2018; 65 Capucci (10.1016/j.virusres.2023.199257_bib0014) 1996; 70 Wang (10.1016/j.virusres.2023.199257_bib0063) 2013; 9 Le Gall-Recule (10.1016/j.virusres.2023.199257_bib0037) 2011; 410 Velarde (10.1016/j.virusres.2023.199257_bib0060) 2021; 68 Martin (10.1016/j.virusres.2023.199257_bib0048) 2015; 1 Strive (10.1016/j.virusres.2023.199257_bib0058) 2009; 384 Capucci (10.1016/j.virusres.2023.199257_bib0011) 2017 McIntosh (10.1016/j.virusres.2023.199257_bib0049) 2007; 4 Cavadini (10.1016/j.virusres.2023.199257_bib0016) 2021; 68 Droillard (10.1016/j.virusres.2023.199257_bib0021) 2018; 7 Marcato (10.1016/j.virusres.2023.199257_bib0047) 1991; 10 Parra (10.1016/j.virusres.2023.199257_bib0055) 1990; 64 Abrantes (10.1016/j.virusres.2023.199257_bib0003) 2012; 43 |
| References_xml | – volume: 43 start-page: 12 year: 2012 ident: bib0003 article-title: Rabbit haemorrhagic disease (RHD) and rabbit haemorrhagic disease virus (RHDV): a review publication-title: Vet. Res. – volume: 44 start-page: 96 year: 2013 ident: bib0056 article-title: The new French 2010 Rabbit Hemorrhagic Disease Virus causes an RHD-like disease in the Sardinian Cape hare (Lepus capensis mediterraneus) publication-title: Vet. Res. – volume: 65 start-page: 983 year: 2018 end-page: 992 ident: bib0057 article-title: Insights into the evolution of the new variant rabbit haemorrhagic disease virus (GI.2) and the identification of novel recombinant strains publication-title: Transbound Emerg. Dis. – volume: 21 start-page: 347 year: 2002 end-page: 358 ident: bib0018 article-title: Rabbit haemorrhagic disease: field epidemiology and the management of wild rabbit populations publication-title: Rev. Sci. Tech. – volume: 4 start-page: 96 year: 2007 ident: bib0049 article-title: A pandemic strain of calicivirus threatens rabbit industries in the Americas publication-title: Virol. J. – volume: 168 start-page: 137 year: 2011 end-page: 138 ident: bib0036 article-title: Detection of a new variant of rabbit haemorrhagic disease virus in France publication-title: Vet. Rec. – volume: 180 start-page: 121 year: 2017 ident: bib0028 article-title: Detection of RHDV2 in European brown hares (Lepus europaeus) in Australia publication-title: Vet. Rec. – volume: 73 start-page: 152 year: 1999 end-page: 160 ident: bib0040 article-title: Full-length human immunodeficiency virus type 1 genomes from subtype C-infected seroconverters in India, with evidence of intersubtype recombination publication-title: J. Virol. – volume: 10 start-page: 14502 year: 2020 end-page: 14504 ident: bib0001 article-title: Recombination at the emergence of the pathogenic rabbit haemorrhagic disease virus Lagovirus europaeus/GI.2 publication-title: Sci. Rep. – volume: 7 start-page: e01224 year: 2018 ident: bib0021 article-title: First complete genome sequence of a hare calicivirus strain isolated from Lepus europaeus publication-title: Microbiol. Resour. Announc. – volume: 98 start-page: 1658 year: 2017 end-page: 1666 ident: bib0038 article-title: Proposal for a unified classification system and nomenclature of lagoviruses publication-title: J. Gen. Virol. – volume: 64 start-page: 3331 year: 1990 end-page: 3336 ident: bib0054 article-title: Identification and characterization of the virus causing rabbit hemorrhagic disease publication-title: J. Virol. – volume: 410 start-page: 395 year: 2011 end-page: 402 ident: bib0037 article-title: Characterisation of a non-pathogenic and non-protective infectious rabbit lagovirus related to RHDV publication-title: Virology – volume: 69 start-page: e394 year: 2022 end-page: e405 ident: bib0005 article-title: Early circulation of rabbit haemorrhagic disease virus type 2 in domestic and wild lagomorphs in southern California, USA (2020-2021) publication-title: Transbound Emerg. Dis. – volume: 10 start-page: 371 year: 1991 end-page: 392 ident: bib0047 article-title: Clinical and pathological features of viral haemorrhagic disease of rabbits and the European brown hare syndrome publication-title: Rev. Sci. Tech. – volume: 184 start-page: 664 year: 1991 end-page: 676 ident: bib0051 article-title: Rabbit hemorrhagic disease virus–molecular cloning and nucleotide sequencing of a calicivirus genome publication-title: Virology – volume: 64 start-page: 1750 year: 2017 end-page: 1761 ident: bib0061 article-title: Spillover events of infection of brown hares (Lepus europaeus) with Rabbit Haemorrhagic Disease Type 2 Virus (RHDV2) caused sporadic cases of an european brown hare syndrome-like disease in Italy and Spain publication-title: Transbound Emerg. Dis. – volume: 10 start-page: 453 year: 1991 end-page: 458 ident: bib0023 article-title: Epidemiology and diagnosis of the European brown hare syndrome in Scandinavian countries: a review publication-title: Rev. Sci. Tech. – volume: 7 start-page: veab080 year: 2021 ident: bib0045 article-title: Frequent intergenotypic recombination between the non-structural and structural genes is a major driver of epidemiological fitness in caliciviruses publication-title: Virus Evol. – volume: 96 start-page: 1309 year: 2015 end-page: 1319 ident: bib0042 article-title: Full genomic analysis of new variant rabbit hemorrhagic disease virus revealed multiple recombination events publication-title: J. Gen. Virol. – volume: 10 start-page: 269 year: 1991 end-page: 310 ident: bib0052 article-title: Hepatitis of viral origin in Leporidae: introduction and aetiological hypotheses publication-title: Rev. Sci. Tech. – volume: 87 start-page: 921 year: 2006 end-page: 926 ident: bib0019 article-title: Recombination of Feline calicivirus within an endemically infected cat colony publication-title: J. Gen. Virol. – volume: 41 start-page: 163 year: 1996 end-page: 172 ident: bib0024 article-title: Rabbit hemorrhagic disease virus (RHDV): ultrastructure and biochemical studies of typical and core-like particles present in liver homogenates publication-title: Virus Res. – volume: 184 start-page: 677 year: 1991 end-page: 686 ident: bib0050 article-title: Genomic and subgenomic RNAs of rabbit hemorrhagic disease virus are both protein-linked and packaged into particles publication-title: Virology – volume: 5 start-page: vez005 year: 2019 ident: bib0044 article-title: The discovery of three new hare lagoviruses reveals unexplored viral diversity in this genus publication-title: Virus Evol. – volume: 21 start-page: 2276 year: 2015 end-page: 2278 ident: bib0026 article-title: Emerging Rabbit Hemorrhagic Disease Virus 2 (RHDVb) publication-title: Australia. Emerg. Infect. Dis. – volume: 16 start-page: 253 year: 1984 end-page: 255 ident: bib0039 article-title: A new viral disease in rabbits publication-title: J. Vet. Diagn. Investig. – volume: 65 start-page: e444 year: 2018 end-page: e456 ident: bib0027 article-title: A strain-specific multiplex RT-PCR for Australian rabbit haemorrhagic disease viruses uncovers a new recombinant virus variant in rabbits and hares publication-title: Transbound Emerg. Dis. – volume: 68 start-page: 509 year: 2021 end-page: 518 ident: bib0016 article-title: Widespread occurrence of the non-pathogenic hare calicivirus (HaCV Lagovirus GII.2) in captive-reared and free-living wild hares in Europe publication-title: Transbound Emerg. Dis. – volume: 35 start-page: 1547 year: 2018 end-page: 1549 ident: bib0030 article-title: MEGA X: Molecular Evolutionary Genetics Analysis across computing platforms publication-title: Mol. Biol. Evol. – volume: 89 start-page: 12217 year: 2015 end-page: 12220 ident: bib0022 article-title: Resolving the origin of rabbit hemorrhagic disease virus: insights from an investigation of the viral stocks released in Australia publication-title: J. Virol. – volume: 126 start-page: 581 year: 1990 ident: bib0032 article-title: Rod-shaped virus-like particles in intestinal contents of three avian species publication-title: Vet. Rec. – volume: 180 start-page: 426 year: 2017 ident: bib0012 article-title: Increased pathogenicity in rabbit haemorrhagic disease virus type 2 (RHDV2) publication-title: Vet. Rec. – volume: 11 start-page: 1079 year: 2005 end-page: 1085 ident: bib0008 article-title: Norovirus recombination in ORF1/ORF2 overlap publication-title: Emerg. Infect. Dis. – volume: 10 start-page: 347 year: 1991 end-page: 370 ident: bib0015 article-title: Diagnosis of viral haemorrhagic disease of rabbits and the European brown hare syndrome publication-title: Rev. Sci. Tech. – volume: 1 start-page: vev003 year: 2015 ident: bib0048 article-title: RDP4: detection and analysis of recombination patterns in virus genomes publication-title: Virus Evol. – volume: 70 start-page: 8614 year: 1996 end-page: 8623 ident: bib0014 article-title: Detection and preliminary characterization of a new rabbit calicivirus related to rabbit hemorrhagic disease virus but nonpathogenic publication-title: J. Virol. – volume: 15 start-page: 1955 year: 2009 end-page: 1962 ident: bib0007 article-title: Novel calicivirus identified in rabbits, Michigan, USA publication-title: Emerg. Infect. Dis. – volume: 162 start-page: 269 year: 2017 end-page: 272 ident: bib0029 article-title: Recombination between G2 and G6 strains of rabbit hemorrhagic disease virus (RHDV) in China publication-title: Arch. Virol. – volume: 88 start-page: 3347 year: 2007 end-page: 3359 ident: bib0009 article-title: Norovirus recombination publication-title: J. Gen. Virol. – volume: 181 start-page: 322 year: 2000 ident: bib0025 article-title: Taxonomy of the caliciviruses publication-title: J. Infect. Dis. – volume: 48 start-page: 70 year: 2017 ident: bib0035 article-title: Large-scale lagovirus disease outbreaks in European brown hares (Lepus europaeus) in France caused by RHDV2 strains spatially shared with rabbits (Oryctolagus cuniculus) publication-title: Vet. Res. – volume: 44 start-page: 81 year: 2013 ident: bib0034 article-title: Emergence of a new lagovirus related to Rabbit Haemorrhagic Disease Virus publication-title: Vet. Res. – volume: 43 start-page: 401 year: 1996 end-page: 410 ident: bib0033 article-title: Susceptibility of hares and rabbits to the European brown hare syndrome virus (EBHSV) and rabbit haemorrhagic disease virus (RHDV) under experimental conditions publication-title: Zentralbl Veterinarmed B – volume: 24 start-page: 22 year: 2018 end-page: 31 ident: bib0046 article-title: Detection and circulation of a novel Rabbit Hemorrhagic Disease Virus in Australia publication-title: Emerg. Infect. Dis. – volume: 7 start-page: 13599 year: 2017 end-page: 13602 ident: bib0043 article-title: Characterization of old RHDV strains by complete genome sequencing identifies a novel genetic group publication-title: Sci. Rep. – volume: 9 year: 2013 ident: bib0063 article-title: Atomic model of rabbit hemorrhagic disease virus by cryo-electron microscopy and crystallography publication-title: PLoS Pathog. – volume: 11 start-page: 910 year: 2020 ident: bib0002 article-title: Retrospective analysis shows that most RHDV GI.1 strains circulating since the late 1990s in France and Sweden were recombinant GI.3P-GI.1d strains publication-title: Genes (Basel) – volume: 34 start-page: 221 year: 1998 end-page: 227 ident: bib0053 article-title: The initial impact of rabbit hemorrhagic disease on European rabbit populations in South Australia publication-title: J. Wildl. Dis. – volume: 33 start-page: 732 year: 2021 end-page: 735 ident: bib0064 article-title: Clinical and pathologic findings in an outbreak in rabbits of natural infection by rabbit hemorrhagic disease virus 2 in the northwestern United States publication-title: J. Vet. Diagn. Invest. – volume: 97 start-page: 642 year: 2014 end-page: 645 ident: bib0010 article-title: Detection of the new emerging rabbit haemorrhagic disease type 2 virus (RHDV2) in Sicily from rabbit (Oryctolagus cuniculus) and Italian hare (Lepus corsicanus) publication-title: Res. Vet. Sci. – volume: 68 start-page: 3187 year: 2021 end-page: 3193 ident: bib0060 article-title: Spillover event of recombinant Lagovirus europaeus/GI.2 into the Iberian hare (Lepus granatensis) in Spain publication-title: Transbound Emerg. Dis. – volume: 6 start-page: veaa080 year: 2020 ident: bib0059 article-title: Full-genome sequencing of German rabbit haemorrhagic disease virus uncovers recombination between RHDV (GI.2) and EBHSV (GII.1) publication-title: Virus Evol. – volume: 64 start-page: 4013 year: 1990 end-page: 4015 ident: bib0055 article-title: Purification and characterization of a calicivirus as the causative agent of a lethal hemorrhagic disease in rabbits publication-title: J. Virol. – volume: 124 start-page: 563 year: 2000 end-page: 576 ident: bib0017 article-title: Use of ELISAs in field studies of rabbit haemorrhagic disease (RHD) in Australia publication-title: Epidemiol. Infect. – volume: 100 start-page: 1469 year: 2019 end-page: 1470 ident: bib0062 article-title: ICTV virus taxonomy profile: caliciviridae publication-title: J. Gen. Virol. – year: 2023 ident: bib0065 article-title: Manual of Diagnostic Tests and Vaccines For Terrestrial Animals – volume: 37 start-page: 221 year: 1995 end-page: 238 ident: bib0013 article-title: Antigenicity of the rabbit hemorrhagic disease virus studied by its reactivity with monoclonal antibodies publication-title: Virus Res. – year: 2017 ident: bib0011 article-title: Rabbit Hemorrhagic Disease Virus and European Brown Hare Syndrome Virus – volume: 10 start-page: 883 year: 2021 ident: bib0006 article-title: Multiple introductions of rabbit hemorrhagic disease virus lagovirus europaeus/GI.2 in Africa publication-title: Biology (Basel) – volume: 92 start-page: e01759 year: 2018 ident: bib0041 article-title: Host-specific glycans are correlated with susceptibility to infection by lagoviruses, but not with their virulence publication-title: J. Virol. – volume: 46 start-page: 13 year: 2015 end-page: 14 ident: bib0031 article-title: Field and experimental data indicate that the eastern cottontail (Sylvilagus floridanus) is susceptible to infection with European brown hare syndrome (EBHS) virus and not with rabbit haemorrhagic disease (RHD) virus publication-title: Vet. Res. – volume: 33 start-page: 728 year: 2021 end-page: 731 ident: bib0004 article-title: Outbreak of rabbit hemorrhagic disease virus 2 in the southwestern United States: first detections in southern California publication-title: J. Vet. Diagn. Invest. – volume: 18 start-page: 2009 year: 2012 end-page: 2012 ident: bib0020 article-title: Variant rabbit hemorrhagic disease virus in young rabbits publication-title: Spain. Emerg. Infect Dis. – volume: 384 start-page: 97 year: 2009 end-page: 105 ident: bib0058 article-title: Identification and partial characterisation of a new Lagovirus in Australian wild rabbits publication-title: Virology – volume: 64 start-page: 3331 year: 1990 ident: 10.1016/j.virusres.2023.199257_bib0054 article-title: Identification and characterization of the virus causing rabbit hemorrhagic disease publication-title: J. Virol. doi: 10.1128/jvi.64.7.3331-3336.1990 – volume: 180 start-page: 426 year: 2017 ident: 10.1016/j.virusres.2023.199257_bib0012 article-title: Increased pathogenicity in rabbit haemorrhagic disease virus type 2 (RHDV2) publication-title: Vet. Rec. doi: 10.1136/vr.104132 – volume: 126 start-page: 581 year: 1990 ident: 10.1016/j.virusres.2023.199257_bib0032 article-title: Rod-shaped virus-like particles in intestinal contents of three avian species publication-title: Vet. Rec. – volume: 7 start-page: 13599 year: 2017 ident: 10.1016/j.virusres.2023.199257_bib0043 article-title: Characterization of old RHDV strains by complete genome sequencing identifies a novel genetic group publication-title: Sci. Rep. doi: 10.1038/s41598-017-13902-2 – volume: 92 start-page: e01759 year: 2018 ident: 10.1016/j.virusres.2023.199257_bib0041 article-title: Host-specific glycans are correlated with susceptibility to infection by lagoviruses, but not with their virulence publication-title: J. Virol. doi: 10.1128/JVI.01759-17 – volume: 9 year: 2013 ident: 10.1016/j.virusres.2023.199257_bib0063 article-title: Atomic model of rabbit hemorrhagic disease virus by cryo-electron microscopy and crystallography publication-title: PLoS Pathog. doi: 10.1371/journal.ppat.1003132 – volume: 16 start-page: 253 year: 1984 ident: 10.1016/j.virusres.2023.199257_bib0039 article-title: A new viral disease in rabbits publication-title: J. Vet. Diagn. Investig. – volume: 6 start-page: veaa080 year: 2020 ident: 10.1016/j.virusres.2023.199257_bib0059 article-title: Full-genome sequencing of German rabbit haemorrhagic disease virus uncovers recombination between RHDV (GI.2) and EBHSV (GII.1) publication-title: Virus Evol. doi: 10.1093/ve/veaa080 – volume: 180 start-page: 121 year: 2017 ident: 10.1016/j.virusres.2023.199257_bib0028 article-title: Detection of RHDV2 in European brown hares (Lepus europaeus) in Australia publication-title: Vet. Rec. doi: 10.1136/vr.104034 – volume: 35 start-page: 1547 year: 2018 ident: 10.1016/j.virusres.2023.199257_bib0030 article-title: MEGA X: Molecular Evolutionary Genetics Analysis across computing platforms publication-title: Mol. Biol. Evol. doi: 10.1093/molbev/msy096 – volume: 44 start-page: 96 year: 2013 ident: 10.1016/j.virusres.2023.199257_bib0056 article-title: The new French 2010 Rabbit Hemorrhagic Disease Virus causes an RHD-like disease in the Sardinian Cape hare (Lepus capensis mediterraneus) publication-title: Vet. Res. doi: 10.1186/1297-9716-44-96 – volume: 162 start-page: 269 year: 2017 ident: 10.1016/j.virusres.2023.199257_bib0029 article-title: Recombination between G2 and G6 strains of rabbit hemorrhagic disease virus (RHDV) in China publication-title: Arch. Virol. doi: 10.1007/s00705-016-3082-6 – volume: 184 start-page: 664 year: 1991 ident: 10.1016/j.virusres.2023.199257_bib0051 article-title: Rabbit hemorrhagic disease virus–molecular cloning and nucleotide sequencing of a calicivirus genome publication-title: Virology doi: 10.1016/0042-6822(91)90436-F – volume: 98 start-page: 1658 year: 2017 ident: 10.1016/j.virusres.2023.199257_bib0038 article-title: Proposal for a unified classification system and nomenclature of lagoviruses publication-title: J. Gen. Virol. doi: 10.1099/jgv.0.000840 – volume: 21 start-page: 347 year: 2002 ident: 10.1016/j.virusres.2023.199257_bib0018 article-title: Rabbit haemorrhagic disease: field epidemiology and the management of wild rabbit populations publication-title: Rev. Sci. Tech. doi: 10.20506/rst.21.2.1337 – volume: 87 start-page: 921 year: 2006 ident: 10.1016/j.virusres.2023.199257_bib0019 article-title: Recombination of Feline calicivirus within an endemically infected cat colony publication-title: J. Gen. Virol. doi: 10.1099/vir.0.81537-0 – volume: 43 start-page: 12 year: 2012 ident: 10.1016/j.virusres.2023.199257_bib0003 article-title: Rabbit haemorrhagic disease (RHD) and rabbit haemorrhagic disease virus (RHDV): a review publication-title: Vet. Res. doi: 10.1186/1297-9716-43-12 – volume: 34 start-page: 221 year: 1998 ident: 10.1016/j.virusres.2023.199257_bib0053 article-title: The initial impact of rabbit hemorrhagic disease on European rabbit populations in South Australia publication-title: J. Wildl. Dis. doi: 10.7589/0090-3558-34.2.221 – volume: 64 start-page: 4013 year: 1990 ident: 10.1016/j.virusres.2023.199257_bib0055 article-title: Purification and characterization of a calicivirus as the causative agent of a lethal hemorrhagic disease in rabbits publication-title: J. Virol. doi: 10.1128/jvi.64.8.4013-4015.1990 – volume: 68 start-page: 509 issue: 2 year: 2021 ident: 10.1016/j.virusres.2023.199257_bib0016 article-title: Widespread occurrence of the non-pathogenic hare calicivirus (HaCV Lagovirus GII.2) in captive-reared and free-living wild hares in Europe publication-title: Transbound Emerg. Dis. doi: 10.1111/tbed.13706 – volume: 384 start-page: 97 year: 2009 ident: 10.1016/j.virusres.2023.199257_bib0058 article-title: Identification and partial characterisation of a new Lagovirus in Australian wild rabbits publication-title: Virology doi: 10.1016/j.virol.2008.11.004 – volume: 88 start-page: 3347 year: 2007 ident: 10.1016/j.virusres.2023.199257_bib0009 article-title: Norovirus recombination publication-title: J. Gen. Virol. doi: 10.1099/vir.0.83321-0 – volume: 65 start-page: e444 year: 2018 ident: 10.1016/j.virusres.2023.199257_bib0027 article-title: A strain-specific multiplex RT-PCR for Australian rabbit haemorrhagic disease viruses uncovers a new recombinant virus variant in rabbits and hares publication-title: Transbound Emerg. Dis. doi: 10.1111/tbed.12779 – volume: 33 start-page: 728 year: 2021 ident: 10.1016/j.virusres.2023.199257_bib0004 article-title: Outbreak of rabbit hemorrhagic disease virus 2 in the southwestern United States: first detections in southern California publication-title: J. Vet. Diagn. Invest. doi: 10.1177/10406387211006353 – volume: 73 start-page: 152 issue: 1 year: 1999 ident: 10.1016/j.virusres.2023.199257_bib0040 article-title: Full-length human immunodeficiency virus type 1 genomes from subtype C-infected seroconverters in India, with evidence of intersubtype recombination publication-title: J. Virol. doi: 10.1128/JVI.73.1.152-160.1999 – volume: 124 start-page: 563 year: 2000 ident: 10.1016/j.virusres.2023.199257_bib0017 article-title: Use of ELISAs in field studies of rabbit haemorrhagic disease (RHD) in Australia publication-title: Epidemiol. Infect. doi: 10.1017/S0950268899003994 – volume: 410 start-page: 395 year: 2011 ident: 10.1016/j.virusres.2023.199257_bib0037 article-title: Characterisation of a non-pathogenic and non-protective infectious rabbit lagovirus related to RHDV publication-title: Virology doi: 10.1016/j.virol.2010.12.001 – volume: 21 start-page: 2276 year: 2015 ident: 10.1016/j.virusres.2023.199257_bib0026 article-title: Emerging Rabbit Hemorrhagic Disease Virus 2 (RHDVb) publication-title: Australia. Emerg. Infect. Dis. doi: 10.3201/eid2112.151210 – volume: 89 start-page: 12217 year: 2015 ident: 10.1016/j.virusres.2023.199257_bib0022 article-title: Resolving the origin of rabbit hemorrhagic disease virus: insights from an investigation of the viral stocks released in Australia publication-title: J. Virol. doi: 10.1128/JVI.01937-15 – volume: 18 start-page: 2009 year: 2012 ident: 10.1016/j.virusres.2023.199257_bib0020 article-title: Variant rabbit hemorrhagic disease virus in young rabbits publication-title: Spain. Emerg. Infect Dis. doi: 10.3201/eid1812.120341 – volume: 1 start-page: vev003 issue: 1 year: 2015 ident: 10.1016/j.virusres.2023.199257_bib0048 article-title: RDP4: detection and analysis of recombination patterns in virus genomes publication-title: Virus Evol. doi: 10.1093/ve/vev003 – volume: 68 start-page: 3187 year: 2021 ident: 10.1016/j.virusres.2023.199257_bib0060 article-title: Spillover event of recombinant Lagovirus europaeus/GI.2 into the Iberian hare (Lepus granatensis) in Spain publication-title: Transbound Emerg. Dis. doi: 10.1111/tbed.14264 – volume: 24 start-page: 22 year: 2018 ident: 10.1016/j.virusres.2023.199257_bib0046 article-title: Detection and circulation of a novel Rabbit Hemorrhagic Disease Virus in Australia publication-title: Emerg. Infect. Dis. doi: 10.3201/eid2401.170412 – volume: 100 start-page: 1469 year: 2019 ident: 10.1016/j.virusres.2023.199257_bib0062 article-title: ICTV virus taxonomy profile: caliciviridae publication-title: J. Gen. Virol. doi: 10.1099/jgv.0.001332 – volume: 69 start-page: e394 year: 2022 ident: 10.1016/j.virusres.2023.199257_bib0005 article-title: Early circulation of rabbit haemorrhagic disease virus type 2 in domestic and wild lagomorphs in southern California, USA (2020-2021) publication-title: Transbound Emerg. Dis. doi: 10.1111/tbed.14315 – volume: 11 start-page: 1079 year: 2005 ident: 10.1016/j.virusres.2023.199257_bib0008 article-title: Norovirus recombination in ORF1/ORF2 overlap publication-title: Emerg. Infect. Dis. doi: 10.3201/eid1107.041273 – volume: 33 start-page: 732 year: 2021 ident: 10.1016/j.virusres.2023.199257_bib0064 article-title: Clinical and pathologic findings in an outbreak in rabbits of natural infection by rabbit hemorrhagic disease virus 2 in the northwestern United States publication-title: J. Vet. Diagn. Invest. doi: 10.1177/10406387211022466 – volume: 7 start-page: e01224 year: 2018 ident: 10.1016/j.virusres.2023.199257_bib0021 article-title: First complete genome sequence of a hare calicivirus strain isolated from Lepus europaeus publication-title: Microbiol. Resour. Announc. doi: 10.1128/mra.01224-18 – volume: 96 start-page: 1309 year: 2015 ident: 10.1016/j.virusres.2023.199257_bib0042 article-title: Full genomic analysis of new variant rabbit hemorrhagic disease virus revealed multiple recombination events publication-title: J. Gen. Virol. doi: 10.1099/vir.0.000070 – volume: 10 start-page: 883 year: 2021 ident: 10.1016/j.virusres.2023.199257_bib0006 article-title: Multiple introductions of rabbit hemorrhagic disease virus lagovirus europaeus/GI.2 in Africa publication-title: Biology (Basel) – volume: 41 start-page: 163 year: 1996 ident: 10.1016/j.virusres.2023.199257_bib0024 article-title: Rabbit hemorrhagic disease virus (RHDV): ultrastructure and biochemical studies of typical and core-like particles present in liver homogenates publication-title: Virus Res. doi: 10.1016/0168-1702(96)01285-3 – volume: 10 start-page: 269 year: 1991 ident: 10.1016/j.virusres.2023.199257_bib0052 article-title: Hepatitis of viral origin in Leporidae: introduction and aetiological hypotheses publication-title: Rev. Sci. Tech. doi: 10.20506/rst.10.2.549 – volume: 7 start-page: veab080 year: 2021 ident: 10.1016/j.virusres.2023.199257_bib0045 article-title: Frequent intergenotypic recombination between the non-structural and structural genes is a major driver of epidemiological fitness in caliciviruses publication-title: Virus Evol. doi: 10.1093/ve/veab080 – volume: 65 start-page: 983 year: 2018 ident: 10.1016/j.virusres.2023.199257_bib0057 article-title: Insights into the evolution of the new variant rabbit haemorrhagic disease virus (GI.2) and the identification of novel recombinant strains publication-title: Transbound Emerg. Dis. doi: 10.1111/tbed.12830 – year: 2017 ident: 10.1016/j.virusres.2023.199257_bib0011 – volume: 181 start-page: 322 issue: 2 year: 2000 ident: 10.1016/j.virusres.2023.199257_bib0025 article-title: Taxonomy of the caliciviruses publication-title: J. Infect. Dis. doi: 10.1086/315591 – volume: 184 start-page: 677 year: 1991 ident: 10.1016/j.virusres.2023.199257_bib0050 article-title: Genomic and subgenomic RNAs of rabbit hemorrhagic disease virus are both protein-linked and packaged into particles publication-title: Virology doi: 10.1016/0042-6822(91)90437-G – volume: 15 start-page: 1955 year: 2009 ident: 10.1016/j.virusres.2023.199257_bib0007 article-title: Novel calicivirus identified in rabbits, Michigan, USA publication-title: Emerg. Infect. Dis. doi: 10.3201/eid1512.090839 – volume: 10 start-page: 371 year: 1991 ident: 10.1016/j.virusres.2023.199257_bib0047 article-title: Clinical and pathological features of viral haemorrhagic disease of rabbits and the European brown hare syndrome publication-title: Rev. Sci. Tech. doi: 10.20506/rst.10.2.560 – volume: 97 start-page: 642 year: 2014 ident: 10.1016/j.virusres.2023.199257_bib0010 article-title: Detection of the new emerging rabbit haemorrhagic disease type 2 virus (RHDV2) in Sicily from rabbit (Oryctolagus cuniculus) and Italian hare (Lepus corsicanus) publication-title: Res. Vet. Sci. doi: 10.1016/j.rvsc.2014.10.008 – volume: 4 start-page: 96 year: 2007 ident: 10.1016/j.virusres.2023.199257_bib0049 article-title: A pandemic strain of calicivirus threatens rabbit industries in the Americas publication-title: Virol. J. doi: 10.1186/1743-422X-4-96 – volume: 64 start-page: 1750 year: 2017 ident: 10.1016/j.virusres.2023.199257_bib0061 article-title: Spillover events of infection of brown hares (Lepus europaeus) with Rabbit Haemorrhagic Disease Type 2 Virus (RHDV2) caused sporadic cases of an european brown hare syndrome-like disease in Italy and Spain publication-title: Transbound Emerg. Dis. doi: 10.1111/tbed.12562 – volume: 44 start-page: 81 year: 2013 ident: 10.1016/j.virusres.2023.199257_bib0034 article-title: Emergence of a new lagovirus related to Rabbit Haemorrhagic Disease Virus publication-title: Vet. Res. doi: 10.1186/1297-9716-44-81 – volume: 37 start-page: 221 year: 1995 ident: 10.1016/j.virusres.2023.199257_bib0013 article-title: Antigenicity of the rabbit hemorrhagic disease virus studied by its reactivity with monoclonal antibodies publication-title: Virus Res. doi: 10.1016/0168-1702(95)00033-M – volume: 10 start-page: 347 year: 1991 ident: 10.1016/j.virusres.2023.199257_bib0015 article-title: Diagnosis of viral haemorrhagic disease of rabbits and the European brown hare syndrome publication-title: Rev. Sci. Tech. doi: 10.20506/rst.10.2.561 – volume: 168 start-page: 137 year: 2011 ident: 10.1016/j.virusres.2023.199257_bib0036 article-title: Detection of a new variant of rabbit haemorrhagic disease virus in France publication-title: Vet. Rec. doi: 10.1136/vr.d697 – volume: 11 start-page: 910 year: 2020 ident: 10.1016/j.virusres.2023.199257_bib0002 article-title: Retrospective analysis shows that most RHDV GI.1 strains circulating since the late 1990s in France and Sweden were recombinant GI.3P-GI.1d strains publication-title: Genes (Basel) doi: 10.3390/genes11080910 – volume: 5 start-page: vez005 year: 2019 ident: 10.1016/j.virusres.2023.199257_bib0044 article-title: The discovery of three new hare lagoviruses reveals unexplored viral diversity in this genus publication-title: Virus Evol. doi: 10.1093/ve/vez005 – volume: 48 start-page: 70 year: 2017 ident: 10.1016/j.virusres.2023.199257_bib0035 article-title: Large-scale lagovirus disease outbreaks in European brown hares (Lepus europaeus) in France caused by RHDV2 strains spatially shared with rabbits (Oryctolagus cuniculus) publication-title: Vet. Res. doi: 10.1186/s13567-017-0473-y – year: 2023 ident: 10.1016/j.virusres.2023.199257_bib0065 – volume: 43 start-page: 401 year: 1996 ident: 10.1016/j.virusres.2023.199257_bib0033 article-title: Susceptibility of hares and rabbits to the European brown hare syndrome virus (EBHSV) and rabbit haemorrhagic disease virus (RHDV) under experimental conditions publication-title: Zentralbl Veterinarmed B – volume: 10 start-page: 14502 year: 2020 ident: 10.1016/j.virusres.2023.199257_bib0001 article-title: Recombination at the emergence of the pathogenic rabbit haemorrhagic disease virus Lagovirus europaeus/GI.2 publication-title: Sci. Rep. doi: 10.1038/s41598-020-71303-4 – volume: 70 start-page: 8614 year: 1996 ident: 10.1016/j.virusres.2023.199257_bib0014 article-title: Detection and preliminary characterization of a new rabbit calicivirus related to rabbit hemorrhagic disease virus but nonpathogenic publication-title: J. Virol. doi: 10.1128/jvi.70.12.8614-8623.1996 – volume: 46 start-page: 13 year: 2015 ident: 10.1016/j.virusres.2023.199257_bib0031 article-title: Field and experimental data indicate that the eastern cottontail (Sylvilagus floridanus) is susceptible to infection with European brown hare syndrome (EBHS) virus and not with rabbit haemorrhagic disease (RHD) virus publication-title: Vet. Res. doi: 10.1186/s13567-015-0149-4 – volume: 10 start-page: 453 year: 1991 ident: 10.1016/j.virusres.2023.199257_bib0023 article-title: Epidemiology and diagnosis of the European brown hare syndrome in Scandinavian countries: a review publication-title: Rev. Sci. Tech. doi: 10.20506/rst.10.2.555 |
| SSID | ssj0006376 |
| Score | 2.4431129 |
| Snippet | •RHDV2_Bg12 originated in a hare through recombination at the RdP-VP60 junction.•Structural genes come from RHDV2, the non-structural ones from a new hare... The genus Lagovirus, belonging to the family Caliciviridae, emerged around the 1980s. It includes highly pathogenic species, rabbit hemorrhagic disease virus... |
| SourceID | doaj proquest pubmed crossref elsevier |
| SourceType | Open Website Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 199257 |
| SubjectTerms | Animal experiments Animals Australia Biological Evolution Caliciviridae Infections - epidemiology Caliciviridae Infections - veterinary European brown hare syndrome virus family genes genotype genus Hares Hemorrhagic Disease Virus, Rabbit - genetics hepatitis host specificity Italy Lagovirus Lepus europaeus monitoring Phylogeny Rabbit hemorrhagic disease virus Rabbits Recombination Recombination, Genetic RHDV2 species Vesivirus Virus selection viruses |
| Title | Recombination between non-structural and structural genes as a mechanism of selection in lagoviruses: The evolutionary dead-end of an RHDV2 isolated from European hare |
| URI | https://dx.doi.org/10.1016/j.virusres.2023.199257 https://www.ncbi.nlm.nih.gov/pubmed/38347757 https://www.proquest.com/docview/2926080296 https://www.proquest.com/docview/3040356692 https://doaj.org/article/9ecabcfaad3042bf8d28a3dadb2c1c4c |
| Volume | 339 |
| WOSCitedRecordID | wos001166945400001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVAON databaseName: DOAJ Directory of Open Access Journals customDbUrl: eissn: 1872-7492 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0006376 issn: 0168-1702 databaseCode: DOA dateStart: 20230101 isFulltext: true titleUrlDefault: https://www.doaj.org/ providerName: Directory of Open Access Journals – providerCode: PRVESC databaseName: Elsevier SD Freedom Collection Journals 2021 customDbUrl: eissn: 1872-7492 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0006376 issn: 0168-1702 databaseCode: AIEXJ dateStart: 19950101 isFulltext: true titleUrlDefault: https://www.sciencedirect.com providerName: Elsevier |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Lb9QwELaggMQF8WZ5rIzENTRxEj-4FWhVEKoQArQ3a-JxSqpuFu22K_UX8TeZyWO1HKq9IOWSyLY8ns-eGcf-Rog3KSqNUekkFLpIikJhAqrWCaQZli6D4GKXteSLOTmxs5n7upXqi8-E9fTA_cDtuxigCjUAcuBd1RaVhRwBKxWyUARefVPjxmBqWIM1zZut-8Bnb9fN8pJsDhN0q5yv6Ck2SFumqGPs_8ciXedxdpbn6L64N7iM8qDv6gNxI7YPxZ0-ieTVI_GHI8g5BbjdGMvh4JWksD7pyWGZWENCi3Lr9ZSXOAn0yHnky7_Nai4XtVx1aXG4naaV53C66CSKq3eS8CTjegAqLK8kEjqSSM1SNWjlt-OPP5VsCMrkvaLkayty3OqXv2AZH4sfR4ffPxwnQ_qFJJCTc5FEGxRqGmmDZMDAQFoqCKbO0MSiTIHiWcwcKrQ1qGArZOq2SP4DOhutsfkTsUeyxmdCkgJzdDpYTi9jdQppqHVUVcnUNMHgRJSjJnwYuMk5Rca5Hw-hnflRg5416HsNTsT-pt7vnp1jZ433rOhNaWbX7j4Q5vyAOb8LcxPhRpj4wVHpHRBqqtnZgdcjrjzNZP49A21cXFIhR7GlTZXT15eh_qQ5eeBOTcTTHpQbUXKbF8aU5vn_EPGFuEudLrrNJvVS7BFA4ytxO6wvmtVyKm6amZ2KWwefDmefp93U-wvRtDnv |
| linkProvider | Directory of Open Access Journals |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Recombination+between+non-structural+and+structural+genes+as+a+mechanism+of+selection+in+lagoviruses%3A+The+evolutionary+dead-end+of+an+RHDV2+isolated+from+European+hare&rft.jtitle=Virus+research&rft.au=Cavadini%2C+Patrizia&rft.au=Trogu%2C+Tiziana&rft.au=Velarde%2C+Roser&rft.au=Lavazza%2C+Antonio&rft.date=2024-01-02&rft.issn=0168-1702&rft.volume=339+p.199257-&rft_id=info:doi/10.1016%2Fj.virusres.2023.199257&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0168-1702&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0168-1702&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0168-1702&client=summon |