Application of glutathione depletion in cancer therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy

Glutathione (GSH) is an important member of cellular antioxidative system. In cancer cells, a high level of GSH is indispensable to scavenge excessive reactive oxygen species (ROS) and detoxify xenobiotics, which make it a potential target for cancer therapy. Plenty of studies have shown that loss o...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biomaterials Jg. 277; S. 121110
Hauptverfasser:	Niu, Boyi, Liao, Kaixin, Zhou, Yixian, Wen, Ting, Quan, Guilan, Pan, Xin, Wu, Chuanbin
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Elsevier Ltd 01.10.2021
Schlagworte:	biocompatible materials Cancer therapy drug delivery systems Drug resistance Ferroptosis glutathione Glutathione depletion metabolism Nanomaterials oxidative stress photochemotherapy Reactive oxygen species xenobiotics Ferroptosis Nanomaterials Reactive oxygen species Glutathione depletion Drug resistance Cancer therapy
ISSN:	0142-9612, 1878-5905, 1878-5905
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!