Lamins at the crossroads of mechanosignaling

The intermediate filament proteins, A- and B-type lamins, form the nuclear lamina scaffold adjacent to the inner nuclear membrane. B-type lamins confer elasticity, while A-type lamins lend viscosity and stiffness to nuclei. Lamins also contribute to chromatin regulation and various signaling pathway...

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Bibliographic Details
Published in:	Genes & development Vol. 29; no. 3; p. 225
Main Authors:	Osmanagic-Myers, Selma, Dechat, Thomas, Foisner, Roland
Format:	Journal Article
Language:	English
Published:	United States 01.02.2015
Subjects:	Animals Cell Movement Extracellular Matrix - genetics Extracellular Matrix - metabolism Gene Expression Regulation Humans Lamins - chemistry Lamins - metabolism Mechanotransduction, Cellular Mutation LINC complex mechanosensing lamins cytoskeleton mechanotransduction extracellular matrix
ISSN:	1549-5477, 1549-5477
Online Access:	Get more information
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