A multiple-template approach to protein threading

Most threading methods predict the structure of a protein using only a single template. Due to the increasing number of solved structures, a protein without solved structure is very likely to have more than one similar template structures. Therefore, a natural question to ask is if we can improve mo...

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Veröffentlicht in:	Proteins, structure, function, and bioinformatics Jg. 79; H. 6; S. 1930 - 1939
Hauptverfasser:	Peng, Jian, Xu, Jinbo
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.06.2011 Wiley Subscription Services, Inc
Schlagworte:	Algorithms Databases, Protein multiple sequence/template alignment multiple-template threading probabilistic alignment matrix probabilistic-consistency algorithm Protein Conformation protein modeling Proteins - chemistry Sequence Alignment - methods
ISSN:	0887-3585, 1097-0134, 1097-0134
Online-Zugang:	Volltext
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