Potentiation of evoked calcitonin gene-related peptide release from oral mucosa: a potential basis for the pro-inflammatory effects of nicotine

Inflammation of the buccal mucosa, gingiva and periodontal tissues is a significant problem in users of nicotine‐containing tobacco products; however, the potential role of nicotine in the development of this inflammation is unclear. In many tissues, nicotine, acting through nicotinic acetylcholine...

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Bibliographic Details
Published in:	The European journal of neuroscience Vol. 18; no. 9; pp. 2515 - 2526
Main Authors:	Dussor, Gregory O., Leong, Anthony S., Gracia, Nicholas B., Kilo, Sonja, Price, Theodore J., Hargreaves, Kenneth M., Flores, Christopher M.
Format:	Journal Article
Language:	English
Published:	Oxford, UK Blackwell Science, Ltd 01.11.2003
Subjects:	Alkaloids - pharmacology Animals Azocines - pharmacology Bridged Bicyclo Compounds, Heterocyclic - pharmacology buccal mucosa Calcitonin Gene-Related Peptide - analysis Calcitonin Gene-Related Peptide - metabolism capsaicin Capsaicin - pharmacology cytisine epibatidine In Situ Hybridization Male Mecamylamine - pharmacology Mouth Mucosa - metabolism Nicotine - agonists Nicotine - antagonists & inhibitors Nicotine - pharmacology nicotinic acetylcholine receptor Nicotinic Agonists - pharmacology Nicotinic Antagonists - pharmacology Pyridines - pharmacology Quinolizines - pharmacology Radioimmunoassay Rats Rats, Sprague-Dawley Receptors, Drug - analysis Receptors, Drug - metabolism Receptors, Nicotinic - analysis Receptors, Nicotinic - drug effects Receptors, Nicotinic - metabolism sensory neuron Trigeminal Ganglion - chemistry
ISSN:	0953-816X, 1460-9568
Online Access:	Get full text
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