Brief angiotensin converting enzyme inhibitor treatment in young spontaneously hypertensive rats reduces blood pressure long-term

Our study examines the long-term cardiovascular effects after a brief period of angiotensin converting enzyme (ACE) inhibitor treatment in young spontaneously hypertensive rats (SHR). SHR were treated with perindopril (3 mg/kg/day) by gavage from 2 to 6, from 6 to 10, or from 2 to 10 weeks of age. S...

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Bibliographic Details

Published in:	Hypertension (Dallas, Tex. 1979) Vol. 16; no. 6; p. 603
Main Authors:	Harrap, S B, Van der Merwe, W M, Griffin, S A, Macpherson, F, Lever, A F
Format:	Journal Article
Language:	English
Published:	United States 01.12.1990
Subjects:	Angiotensin II - pharmacology Angiotensin-Converting Enzyme Inhibitors - pharmacology Animals Antihypertensive Agents - pharmacology Blood Pressure - drug effects Blood Vessels - anatomy & histology Blood Vessels - drug effects Cardiovascular Physiological Phenomena Hemodynamics Hypertension - drug therapy Indoles - pharmacology Perindopril Rats Rats, Inbred SHR - growth & development Time Factors
ISSN:	0194-911X
Online Access:	Get more information
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