Targeted Metabolomics Shows Low Plasma Lysophosphatidylcholine 18:2 Predicts Greater Decline of Gait Speed in Older Adults: The Baltimore Longitudinal Study of Aging

Gait speed is an important measure of lower extremity physical performance in older adults and is predictive of disability and mortality. The biological pathways involved in the decline of lower extremity physical performance are not well understood. We used a targeted metabolomics approach to ident...

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Veröffentlicht in:	The journals of gerontology. Series A, Biological sciences and medical sciences Jg. 74; H. 1; S. 62
Hauptverfasser:	Gonzalez-Freire, Marta, Moaddel, Ruin, Sun, Kai, Fabbri, Elisa, Zhang, Pingbo, Khadeer, Mohammed, Salem, Jr, Norman, Ferrucci, Luigi, Semba, Richard D
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.01.2019
Schlagworte:	Aged Aging - physiology Baltimore - epidemiology Biomarkers - blood Cross-Sectional Studies Female Follow-Up Studies Gait - physiology Geriatric Assessment - methods Humans Incidence Lysophosphatidylcholines - blood Male Metabolomics - methods Middle Aged Mobility Limitation Retrospective Studies Sarcopenia - blood Sarcopenia - epidemiology Sarcopenia - physiopathology Survival Rate - trends Time Factors Walking Speed - physiology Baltimore
ISSN:	1758-535X, 1758-535X
Online-Zugang:	Weitere Angaben
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