Improving acetoin production through construction of a genome-scale metabolic model

Acetoin was widely used in food, medicine, and other industries, because of its unique fragrance. Bacillus amyloliquefaciens was recognized as a safe strain and a promising acetoin producer in fermentation. However, due to the complexity of its metabolic network, it had not been fully utilized. Ther...

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Bibliographic Details
Published in:	Computers in biology and medicine Vol. 158; p. 106833
Main Authors:	Qian, Jinyi, Wang, Yuzhou, Liu, Xiner, Hu, Zijian, Xu, Nan, Wang, Yuetong, Shi, Tianqiong, Ye, Chao
Format:	Journal Article
Language:	English
Published:	United States Elsevier Ltd 01.05.2023 Elsevier Limited
Subjects:	Acetoin Acetoin - metabolism Algorithms Amino acids Automation Bacillus amyloliquefaciens Biosynthesis Carbon Chemical synthesis Enzymes Fermentation Food industry Genes Genome-scale metabolic network model Genomes Glucose isomerase Glucose-6-phosphate isomerase Gram-positive bacteria Industrial production Internal Medicine Ketoglutaric acid Magnesium Medical research Metabolic engineering Metabolic Engineering - methods Metabolic networks Metabolic Networks and Pathways - genetics Metabolism Metabolites Nitrogen Other Potential targets Pyruvic acid Acetoin Potential targets Bacillus amyloliquefaciens Genome-scale metabolic network model
ISSN:	0010-4825, 1879-0534, 1879-0534
Online Access:	Get full text
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