Diagnosing COVID‐19 in the Emergency Department: A Scoping Review of Clinical Examinations, Laboratory Tests, Imaging Accuracy, and Biases

Objective Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) emerged as a global pandemic in early 2020 with rapidly evolving approaches to diagnosing the clinical illness called coronavirus disease (COVID‐19). The primary objective of this scoping review is to synthesize current research...

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Vydáno v:Academic emergency medicine Ročník 27; číslo 8; s. 653 - 670
Hlavní autoři: Carpenter, Christopher R., Mudd, Philip A., West, Colin P., Wilber, Erin, Wilber, Scott T., Zehtabchi, Shahriar
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States Wiley Subscription Services, Inc 01.08.2020
John Wiley and Sons Inc
Témata:
Accuracy
Adult
Coronaviruses
COVID-19 - diagnosis
COVID-19 Testing - statistics & numerical data
Diagnostic Tests, Routine
Editors' Pick
Emergency Service, Hospital
Evidence‐Based Diagnostics
Female
Humans
Laboratories
Medical diagnosis
Pandemics - statistics & numerical data
Physical Examination - statistics & numerical data
SARS-CoV-2 - isolation & purification
Serology
Severe acute respiratory syndrome coronavirus 2
Tomography, X-Ray Computed
ISSN:1069-6563, 1553-2712, 1553-2712
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Abstract Objective Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) emerged as a global pandemic in early 2020 with rapidly evolving approaches to diagnosing the clinical illness called coronavirus disease (COVID‐19). The primary objective of this scoping review is to synthesize current research of the diagnostic accuracy of history, physical examination, routine laboratory tests, real‐time reverse transcription–polymerase chain reaction (rRT‐PCR), immunology tests, and computed tomography (CT) for the emergency department (ED) diagnosis of COVID‐19. Secondary objectives included a synopsis of diagnostic biases likely with current COVID‐19 research as well as corresponding implications of false‐negative and false‐positive results for clinicians and investigators. Methods A Preferred Reporting Items for Systematic Reviews and Meta‐Analyses–Scoping Review (PRISMA‐ScR)–adherent synthesis of COVID‐19 diagnostic accuracy through May 5, 2020, was conducted. The search strategy was designed by a medical librarian and included studies indexed by PubMed and Embase since January 2020. Results A total of 1,907 citations were screened for relevance. Patients without COVID‐19 are rarely reported, so specificity and likelihood ratios were generally unavailable. Fever is the most common finding, while hyposmia and hypogeusia appear useful to rule in COVID‐19. Cough is not consistently present. Lymphopenia is the mostly commonly reported laboratory abnormality and occurs in over 50% of COVID‐19 patients. rRT‐PCR is currently considered the COVID‐19 criterion standard for most diagnostic studies, but a single test sensitivity ranges from 60% to 78%. Multiple reasons for false‐negatives rRT‐PCR exist, including sample site tested and disease stage during which sample was obtained. CT may increase COVID‐19 sensitivity in conjunction with rRT‐PCR, but guidelines for imaging patients most likely to benefit are emerging. IgM and IgG serology levels are undetectable in the first week of COVID‐19, but sensitivity (range = 82% to 100%) and specificity (range = 87% to 100%) are promising. Whether detectable COVID‐19 antibodies correspond to immunity remains unanswered. Current studies do not adhere to accepted diagnostic accuracy reporting standards and likely report significantly biased results if the same tests were to be applied to general ED populations with suspected COVID‐19. Conclusions With the exception of fever and disorders of smell/taste, history and physical examination findings are unhelpful to distinguish COVID‐19 from other infectious conditions that mimic SARS‐CoV‐2 like influenza. Routine laboratory tests are also nondiagnostic, although lymphopenia is a common finding and other abnormalities may predict severe disease. Although rRT‐PCR is the current criterion standard, more inclusive consensus‐based criteria will likely emerge because of the high false‐negative rate of PCR tests. The role of serology and CT in ED assessments remains undefined.
AbstractList Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged as a global pandemic in early 2020 with rapidly evolving approaches to diagnosing the clinical illness called coronavirus disease (COVID-19). The primary objective of this scoping review is to synthesize current research of the diagnostic accuracy of history, physical examination, routine laboratory tests, real-time reverse transcription-polymerase chain reaction (rRT-PCR), immunology tests, and computed tomography (CT) for the emergency department (ED) diagnosis of COVID-19. Secondary objectives included a synopsis of diagnostic biases likely with current COVID-19 research as well as corresponding implications of false-negative and false-positive results for clinicians and investigators.OBJECTIVESevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged as a global pandemic in early 2020 with rapidly evolving approaches to diagnosing the clinical illness called coronavirus disease (COVID-19). The primary objective of this scoping review is to synthesize current research of the diagnostic accuracy of history, physical examination, routine laboratory tests, real-time reverse transcription-polymerase chain reaction (rRT-PCR), immunology tests, and computed tomography (CT) for the emergency department (ED) diagnosis of COVID-19. Secondary objectives included a synopsis of diagnostic biases likely with current COVID-19 research as well as corresponding implications of false-negative and false-positive results for clinicians and investigators.A Preferred Reporting Items for Systematic Reviews and Meta-Analyses-Scoping Review (PRISMA-ScR)-adherent synthesis of COVID-19 diagnostic accuracy through May 5, 2020, was conducted. The search strategy was designed by a medical librarian and included studies indexed by PubMed and Embase since January 2020.METHODSA Preferred Reporting Items for Systematic Reviews and Meta-Analyses-Scoping Review (PRISMA-ScR)-adherent synthesis of COVID-19 diagnostic accuracy through May 5, 2020, was conducted. The search strategy was designed by a medical librarian and included studies indexed by PubMed and Embase since January 2020.A total of 1,907 citations were screened for relevance. Patients without COVID-19 are rarely reported, so specificity and likelihood ratios were generally unavailable. Fever is the most common finding, while hyposmia and hypogeusia appear useful to rule in COVID-19. Cough is not consistently present. Lymphopenia is the mostly commonly reported laboratory abnormality and occurs in over 50% of COVID-19 patients. rRT-PCR is currently considered the COVID-19 criterion standard for most diagnostic studies, but a single test sensitivity ranges from 60% to 78%. Multiple reasons for false-negatives rRT-PCR exist, including sample site tested and disease stage during which sample was obtained. CT may increase COVID-19 sensitivity in conjunction with rRT-PCR, but guidelines for imaging patients most likely to benefit are emerging. IgM and IgG serology levels are undetectable in the first week of COVID-19, but sensitivity (range = 82% to 100%) and specificity (range = 87% to 100%) are promising. Whether detectable COVID-19 antibodies correspond to immunity remains unanswered. Current studies do not adhere to accepted diagnostic accuracy reporting standards and likely report significantly biased results if the same tests were to be applied to general ED populations with suspected COVID-19.RESULTSA total of 1,907 citations were screened for relevance. Patients without COVID-19 are rarely reported, so specificity and likelihood ratios were generally unavailable. Fever is the most common finding, while hyposmia and hypogeusia appear useful to rule in COVID-19. Cough is not consistently present. Lymphopenia is the mostly commonly reported laboratory abnormality and occurs in over 50% of COVID-19 patients. rRT-PCR is currently considered the COVID-19 criterion standard for most diagnostic studies, but a single test sensitivity ranges from 60% to 78%. Multiple reasons for false-negatives rRT-PCR exist, including sample site tested and disease stage during which sample was obtained. CT may increase COVID-19 sensitivity in conjunction with rRT-PCR, but guidelines for imaging patients most likely to benefit are emerging. IgM and IgG serology levels are undetectable in the first week of COVID-19, but sensitivity (range = 82% to 100%) and specificity (range = 87% to 100%) are promising. Whether detectable COVID-19 antibodies correspond to immunity remains unanswered. Current studies do not adhere to accepted diagnostic accuracy reporting standards and likely report significantly biased results if the same tests were to be applied to general ED populations with suspected COVID-19.With the exception of fever and disorders of smell/taste, history and physical examination findings are unhelpful to distinguish COVID-19 from other infectious conditions that mimic SARS-CoV-2 like influenza. Routine laboratory tests are also nondiagnostic, although lymphopenia is a common finding and other abnormalities may predict severe disease. Although rRT-PCR is the current criterion standard, more inclusive consensus-based criteria will likely emerge because of the high false-negative rate of PCR tests. The role of serology and CT in ED assessments remains undefined.CONCLUSIONSWith the exception of fever and disorders of smell/taste, history and physical examination findings are unhelpful to distinguish COVID-19 from other infectious conditions that mimic SARS-CoV-2 like influenza. Routine laboratory tests are also nondiagnostic, although lymphopenia is a common finding and other abnormalities may predict severe disease. Although rRT-PCR is the current criterion standard, more inclusive consensus-based criteria will likely emerge because of the high false-negative rate of PCR tests. The role of serology and CT in ED assessments remains undefined.
ObjectiveSevere acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) emerged as a global pandemic in early 2020 with rapidly evolving approaches to diagnosing the clinical illness called coronavirus disease (COVID‐19). The primary objective of this scoping review is to synthesize current research of the diagnostic accuracy of history, physical examination, routine laboratory tests, real‐time reverse transcription–polymerase chain reaction (rRT‐PCR), immunology tests, and computed tomography (CT) for the emergency department (ED) diagnosis of COVID‐19. Secondary objectives included a synopsis of diagnostic biases likely with current COVID‐19 research as well as corresponding implications of false‐negative and false‐positive results for clinicians and investigators.MethodsA Preferred Reporting Items for Systematic Reviews and Meta‐Analyses–Scoping Review (PRISMA‐ScR)–adherent synthesis of COVID‐19 diagnostic accuracy through May 5, 2020, was conducted. The search strategy was designed by a medical librarian and included studies indexed by PubMed and Embase since January 2020.ResultsA total of 1,907 citations were screened for relevance. Patients without COVID‐19 are rarely reported, so specificity and likelihood ratios were generally unavailable. Fever is the most common finding, while hyposmia and hypogeusia appear useful to rule in COVID‐19. Cough is not consistently present. Lymphopenia is the mostly commonly reported laboratory abnormality and occurs in over 50% of COVID‐19 patients. rRT‐PCR is currently considered the COVID‐19 criterion standard for most diagnostic studies, but a single test sensitivity ranges from 60% to 78%. Multiple reasons for false‐negatives rRT‐PCR exist, including sample site tested and disease stage during which sample was obtained. CT may increase COVID‐19 sensitivity in conjunction with rRT‐PCR, but guidelines for imaging patients most likely to benefit are emerging. IgM and IgG serology levels are undetectable in the first week of COVID‐19, but sensitivity (range = 82% to 100%) and specificity (range = 87% to 100%) are promising. Whether detectable COVID‐19 antibodies correspond to immunity remains unanswered. Current studies do not adhere to accepted diagnostic accuracy reporting standards and likely report significantly biased results if the same tests were to be applied to general ED populations with suspected COVID‐19.ConclusionsWith the exception of fever and disorders of smell/taste, history and physical examination findings are unhelpful to distinguish COVID‐19 from other infectious conditions that mimic SARS‐CoV‐2 like influenza. Routine laboratory tests are also nondiagnostic, although lymphopenia is a common finding and other abnormalities may predict severe disease. Although rRT‐PCR is the current criterion standard, more inclusive consensus‐based criteria will likely emerge because of the high false‐negative rate of PCR tests. The role of serology and CT in ED assessments remains undefined.
Objective Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) emerged as a global pandemic in early 2020 with rapidly evolving approaches to diagnosing the clinical illness called coronavirus disease (COVID‐19). The primary objective of this scoping review is to synthesize current research of the diagnostic accuracy of history, physical examination, routine laboratory tests, real‐time reverse transcription–polymerase chain reaction (rRT‐PCR), immunology tests, and computed tomography (CT) for the emergency department (ED) diagnosis of COVID‐19. Secondary objectives included a synopsis of diagnostic biases likely with current COVID‐19 research as well as corresponding implications of false‐negative and false‐positive results for clinicians and investigators. Methods A Preferred Reporting Items for Systematic Reviews and Meta‐Analyses–Scoping Review (PRISMA‐ScR)–adherent synthesis of COVID‐19 diagnostic accuracy through May 5, 2020, was conducted. The search strategy was designed by a medical librarian and included studies indexed by PubMed and Embase since January 2020. Results A total of 1,907 citations were screened for relevance. Patients without COVID‐19 are rarely reported, so specificity and likelihood ratios were generally unavailable. Fever is the most common finding, while hyposmia and hypogeusia appear useful to rule in COVID‐19. Cough is not consistently present. Lymphopenia is the mostly commonly reported laboratory abnormality and occurs in over 50% of COVID‐19 patients. rRT‐PCR is currently considered the COVID‐19 criterion standard for most diagnostic studies, but a single test sensitivity ranges from 60% to 78%. Multiple reasons for false‐negatives rRT‐PCR exist, including sample site tested and disease stage during which sample was obtained. CT may increase COVID‐19 sensitivity in conjunction with rRT‐PCR, but guidelines for imaging patients most likely to benefit are emerging. IgM and IgG serology levels are undetectable in the first week of COVID‐19, but sensitivity (range = 82% to 100%) and specificity (range = 87% to 100%) are promising. Whether detectable COVID‐19 antibodies correspond to immunity remains unanswered. Current studies do not adhere to accepted diagnostic accuracy reporting standards and likely report significantly biased results if the same tests were to be applied to general ED populations with suspected COVID‐19. Conclusions With the exception of fever and disorders of smell/taste, history and physical examination findings are unhelpful to distinguish COVID‐19 from other infectious conditions that mimic SARS‐CoV‐2 like influenza. Routine laboratory tests are also nondiagnostic, although lymphopenia is a common finding and other abnormalities may predict severe disease. Although rRT‐PCR is the current criterion standard, more inclusive consensus‐based criteria will likely emerge because of the high false‐negative rate of PCR tests. The role of serology and CT in ED assessments remains undefined.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged as a global pandemic in early 2020 with rapidly evolving approaches to diagnosing the clinical illness called coronavirus disease (COVID-19). The primary objective of this scoping review is to synthesize current research of the diagnostic accuracy of history, physical examination, routine laboratory tests, real-time reverse transcription-polymerase chain reaction (rRT-PCR), immunology tests, and computed tomography (CT) for the emergency department (ED) diagnosis of COVID-19. Secondary objectives included a synopsis of diagnostic biases likely with current COVID-19 research as well as corresponding implications of false-negative and false-positive results for clinicians and investigators. A Preferred Reporting Items for Systematic Reviews and Meta-Analyses-Scoping Review (PRISMA-ScR)-adherent synthesis of COVID-19 diagnostic accuracy through May 5, 2020, was conducted. The search strategy was designed by a medical librarian and included studies indexed by PubMed and Embase since January 2020. A total of 1,907 citations were screened for relevance. Patients without COVID-19 are rarely reported, so specificity and likelihood ratios were generally unavailable. Fever is the most common finding, while hyposmia and hypogeusia appear useful to rule in COVID-19. Cough is not consistently present. Lymphopenia is the mostly commonly reported laboratory abnormality and occurs in over 50% of COVID-19 patients. rRT-PCR is currently considered the COVID-19 criterion standard for most diagnostic studies, but a single test sensitivity ranges from 60% to 78%. Multiple reasons for false-negatives rRT-PCR exist, including sample site tested and disease stage during which sample was obtained. CT may increase COVID-19 sensitivity in conjunction with rRT-PCR, but guidelines for imaging patients most likely to benefit are emerging. IgM and IgG serology levels are undetectable in the first week of COVID-19, but sensitivity (range = 82% to 100%) and specificity (range = 87% to 100%) are promising. Whether detectable COVID-19 antibodies correspond to immunity remains unanswered. Current studies do not adhere to accepted diagnostic accuracy reporting standards and likely report significantly biased results if the same tests were to be applied to general ED populations with suspected COVID-19. With the exception of fever and disorders of smell/taste, history and physical examination findings are unhelpful to distinguish COVID-19 from other infectious conditions that mimic SARS-CoV-2 like influenza. Routine laboratory tests are also nondiagnostic, although lymphopenia is a common finding and other abnormalities may predict severe disease. Although rRT-PCR is the current criterion standard, more inclusive consensus-based criteria will likely emerge because of the high false-negative rate of PCR tests. The role of serology and CT in ED assessments remains undefined.
Author West, Colin P.
Carpenter, Christopher R.
Mudd, Philip A.
Wilber, Erin
Wilber, Scott T.
Zehtabchi, Shahriar
AuthorAffiliation 1 From the Department of Emergency Medicine Washington University in St. Louis School of Medicine Emergency Care Research Core St. Louis MO USA
4 and the Asante Rogue Regional Medical Center Medford OR USA
2 the Division of General Internal Medicine Department of Medicine Division of Biomedical Statistics and Informatics Mayo Clinic Rochester MN USA
3 Columbus OH USA
AuthorAffiliation_xml – name: 3 Columbus OH USA
– name: 1 From the Department of Emergency Medicine Washington University in St. Louis School of Medicine Emergency Care Research Core St. Louis MO USA
– name: 4 and the Asante Rogue Regional Medical Center Medford OR USA
– name: 2 the Division of General Internal Medicine Department of Medicine Division of Biomedical Statistics and Informatics Mayo Clinic Rochester MN USA
Author_xml – sequence: 1
  givenname: Christopher R.
  orcidid: 0000-0002-2603-7157
  surname: Carpenter
  fullname: Carpenter, Christopher R.
  email: carpenterc@wustl.edu
  organization: Emergency Care Research Core
– sequence: 2
  givenname: Philip A.
  surname: Mudd
  fullname: Mudd, Philip A.
  organization: Emergency Care Research Core
– sequence: 3
  givenname: Colin P.
  surname: West
  fullname: West, Colin P.
  organization: Mayo Clinic
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  surname: Wilber
  fullname: Wilber, Erin
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  givenname: Scott T.
  surname: Wilber
  fullname: Wilber, Scott T.
  organization: Asante Rogue Regional Medical Center
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  givenname: Shahriar
  surname: Zehtabchi
  fullname: Zehtabchi, Shahriar
BackLink https://www.ncbi.nlm.nih.gov/pubmed/32542934$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1111/all.14316
10.7326/0003-4819-149-11-200812020-00009
10.1016/j.medmal.2020.04.006
10.1001/jama.2020.6437
10.1016/S1473-3099(20)30297-8
10.1111/acem.13225
10.1016/j.jhin.2020.03.012
10.1016/j.arcmed.2020.04.003
10.1016/S0140-6736(20)30211-7
10.1002/jmv.25855
10.7326/M18-0850
10.1136/bmj.m1403
10.1016/j.jclinepi.2016.03.022
10.1093/cid/ciaa345
10.7326/M20-1301
10.1128/JCM.00743-20
10.1016/j.cmi.2020.04.040
10.3934/mbe.2020149
10.1093/cid/ciaa414
10.2196/19054
10.1148/radiol.2020200432
10.1016/S2589-7500(20)30079-0
10.1016/j.mayocp.2020.04.004
10.34172/aim.2020.10
10.1016/j.jhin.2020.03.001
10.1016/j.intimp.2020.106504
10.1093/cid/ciaa443
10.5867/medwave.2020.03.7891
10.1016/j.tmaid.2020.101623
10.1093/cid/ciaa531
10.1067/mem.2003.273
10.1148/radiol.2020201214
10.1016/j.acra.2020.03.002
10.5152/dir.2020.20231
10.1093/cid/ciaa398
10.5858/arpa.2020-0196-LE
10.1111/acem.12255
10.1128/JCM.00783-20
10.1148/ryct.2020200110
10.1016/S1473-3099(20)30113-4
10.1148/radiol.2020200330
10.1093/clinchem/hvaa099
10.1111/j.1538-7836.2008.02944.x
10.1067/mem.2003.274
10.1515/cclm-2020-0240
10.1002/jmv.25822
10.1515/cclm-2020-0187
10.1093/cid/ciaa207
10.1515/cclm-2020-0398
10.1007/s10916-020-01562-1
10.1007/s00330-020-06829-2
10.2214/AJR.20.23202
10.1016/j.ajem.2020.04.016
10.4193/Rhin20.140
10.1370/afm.1192
10.1128/JCM.00760-20
10.1001/jama.2020.4269
10.1148/radiol.2020200343
10.1002/hed.26204
10.1172/jci.insight.137799
10.1148/radiol.2020201160
10.1016/j.jmoldx.2020.03.006
10.1136/bmj.m1328
10.1016/S0196-0644(99)70346-X
10.1016/S1473-3099(20)30241-3
10.1111/acem.13992
10.1002/ijgo.13182
10.1503/cmaj.121286
10.1136/thoraxjnl-2020-214916
10.1111/joim.13089
10.1093/cid/ciaa460
10.1080/14737159.2020.1757437
10.1007/s11606-008-0583-3
10.1002/jmv.25721
10.1007/s11604-020-00958-w
10.1128/JCM.00557-20
10.1111/acem.13071
10.1111/acem.13233
10.1002/alr.22602
10.1016/j.jinf.2020.02.008
10.1016/S1473-3099(20)30247-4
10.2214/AJR.20.23119
10.1007/s11604-020-00967-9
10.1016/j.cca.2020.03.032
10.1093/ajcp/aqaa064
10.1148/radiol.2020201491
10.1016/j.jinf.2020.03.016
10.1111/joim.13091
10.1002/jmv.25770
10.1016/j.jinf.2020.04.005
10.1016/S1473-3099(20)30196-1
10.1148/ryct.2020200034
10.1038/s41374-020-0431-6
10.1186/s41182-020-00201-2
10.15557/PiMR.2020.0024
10.1080/22221751.2020.1756698
10.5811/westjem.2020.1.46760
10.1016/j.ijid.2020.02.050
10.1016/j.dsx.2020.03.015
10.1016/j.ijid.2020.04.023
10.1016/j.jrid.2020.04.003
10.1016/j.crad.2020.03.008
10.1111/1751-7915.13586
10.1016/j.ejrad.2020.108961
10.7326/0003-4819-155-8-201110180-00009
10.1001/jamahealthforum.2020.0448
10.1097/CM9.0000000000000792
10.3390/jcm9030623
10.5152/dir.2020.20260
10.1148/radiol.2020200823
10.1111/ene.14273
10.1016/j.jcv.2020.104374
10.1002/jmv.25763
10.1177/0194599820922992
10.1136/bmj.h5527
10.1016/j.jcv.2020.104384
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ISSN 1069-6563
1553-2712
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Issue 8
Language English
License 2020 by the Society for Academic Emergency Medicine.
This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.
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Notes The authors have no relevant financial information or potential conflicts to disclose.
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References 2020; 20
2020; 163
2013; 20
2018; 169
2020; 369
2020; 126
2020; 17
2020; 127
2020; 58
2020; 14
2020; 13
2008; 149
2008; 6
2020; 323
2011; 155
2016; 78
2020; 8
2020; 7
2020; 6
2020; 5
2020; 2
2020; 295
2020; 95
2020; 51
2020; 94
2020; 296
2020; 93
2020; 92
2020; 172
2020; 9
2020; 215
2008; 23
2020; 48
2020; 133
2020; 44
2003; 42
2011; 2
2020; 42
2020; 84
2020; 81
2020; 80
2017; 24
2009
2020; 105
2020; 38
2020; 100
2020; 35
2013; 185
2020; 34
2020; 506
2020; 75
2020; 153
2020
2020; 395
2015; 351
2020; 150
2020; 27
2020; 26
1999; 33
2016
2020; 23
2020; 22
2020; 21
2013
2016; 23
e_1_2_8_49_1
e_1_2_8_68_1
Khazaei M (e_1_2_8_84_1) 2020; 8
e_1_2_8_132_1
e_1_2_8_5_1
Bendavid E (e_1_2_8_103_1) 2020
e_1_2_8_9_1
e_1_2_8_117_1
e_1_2_8_22_1
e_1_2_8_45_1
e_1_2_8_64_1
e_1_2_8_87_1
Villalba NL (e_1_2_8_26_1) 2020; 7
e_1_2_8_113_1
e_1_2_8_136_1
e_1_2_8_41_1
e_1_2_8_60_1
e_1_2_8_83_1
e_1_2_8_19_1
e_1_2_8_109_1
e_1_2_8_15_1
e_1_2_8_38_1
e_1_2_8_57_1
e_1_2_8_120_1
e_1_2_8_91_1
e_1_2_8_95_1
e_1_2_8_99_1
e_1_2_8_105_1
e_1_2_8_128_1
e_1_2_8_11_1
e_1_2_8_34_1
e_1_2_8_53_1
e_1_2_8_101_1
e_1_2_8_124_1
e_1_2_8_30_1
e_1_2_8_72_1
e_1_2_8_29_1
Kim ES (e_1_2_8_79_1) 2020; 35
e_1_2_8_48_1
Ren X (e_1_2_8_47_1) 2020
Rubin GD (e_1_2_8_111_1) 2020; 296
Carpenter CR (e_1_2_8_116_1) 2013
e_1_2_8_2_1
e_1_2_8_133_1
e_1_2_8_110_1
e_1_2_8_6_1
Mardani R (e_1_2_8_31_1) 2020; 8
e_1_2_8_21_1
e_1_2_8_67_1
e_1_2_8_44_1
e_1_2_8_86_1
e_1_2_8_118_1
e_1_2_8_63_1
e_1_2_8_137_1
e_1_2_8_40_1
e_1_2_8_82_1
e_1_2_8_114_1
e_1_2_8_18_1
e_1_2_8_14_1
e_1_2_8_37_1
e_1_2_8_94_1
e_1_2_8_90_1
e_1_2_8_121_1
e_1_2_8_98_1
e_1_2_8_10_1
e_1_2_8_56_1
e_1_2_8_106_1
e_1_2_8_33_1
e_1_2_8_75_1
e_1_2_8_129_1
e_1_2_8_52_1
Chen SG (e_1_2_8_76_1) 2020
e_1_2_8_71_1
e_1_2_8_125_1
e_1_2_8_28_1
e_1_2_8_24_1
e_1_2_8_3_1
e_1_2_8_81_1
e_1_2_8_130_1
e_1_2_8_7_1
e_1_2_8_20_1
e_1_2_8_43_1
e_1_2_8_66_1
e_1_2_8_89_1
e_1_2_8_119_1
e_1_2_8_138_1
e_1_2_8_62_1
e_1_2_8_85_1
e_1_2_8_115_1
e_1_2_8_134_1
e_1_2_8_17_1
Call SA (e_1_2_8_25_1) 2009
e_1_2_8_13_1
e_1_2_8_36_1
e_1_2_8_59_1
e_1_2_8_70_1
e_1_2_8_122_1
Whitman JD (e_1_2_8_102_1) 2020
e_1_2_8_97_1
e_1_2_8_32_1
e_1_2_8_55_1
e_1_2_8_78_1
e_1_2_8_107_1
e_1_2_8_51_1
e_1_2_8_74_1
e_1_2_8_126_1
e_1_2_8_93_1
Hunter BR (e_1_2_8_123_1) 2016
e_1_2_8_46_1
e_1_2_8_27_1
e_1_2_8_69_1
e_1_2_8_80_1
e_1_2_8_4_1
e_1_2_8_131_1
e_1_2_8_8_1
e_1_2_8_42_1
e_1_2_8_88_1
e_1_2_8_23_1
e_1_2_8_65_1
Abbasi J (e_1_2_8_104_1) 2020
e_1_2_8_112_1
e_1_2_8_61_1
e_1_2_8_135_1
e_1_2_8_39_1
e_1_2_8_35_1
e_1_2_8_16_1
e_1_2_8_58_1
e_1_2_8_92_1
e_1_2_8_96_1
e_1_2_8_100_1
e_1_2_8_77_1
e_1_2_8_127_1
e_1_2_8_12_1
e_1_2_8_54_1
e_1_2_8_108_1
e_1_2_8_73_1
e_1_2_8_50_1
References_xml – volume: 58
  start-page: 1063
  year: 2020
  end-page: 9
  article-title: The critical role of laboratory medicine during coronavirus disease 2019 (COVID‐19) and other viral outbreaks
  publication-title: Clin Chem Lab Med
– year: 2020
  article-title: Limits of detection of six approved RT‐PCR kits for the novel SARS‐coronavirus‐2 (SARS‐CoV‐2)
  publication-title: Clin Chem
– year: 2020
  article-title: Acute‐onset smell and taste disorders in the context of Covid‐19: a pilot multicenter PCR‐based case‐control study
  publication-title: Eur J Neurol
– volume: 6
  start-page: 772
  year: 2008
  end-page: 80
  article-title: Prospective multicenter evaluation of the pulmonary embolism rule‐out criteria
  publication-title: J Thromb Haemost
– volume: 153
  start-page: 715
  year: 2020
  end-page: 8
  article-title: Assessment of specimen pooling to conserve SARS CoV‐2 testing resources
  publication-title: Am J Clin Pathol
– year: 2020
  article-title: Targeted early chest CT in COVID‐19 outbreaks as diagnostic tool for containment of the pandemic ‐ A multinational opinion
  publication-title: Diagn Interv Radiol
– volume: 13
  start-page: 950
  year: 2020
  end-page: 61
  article-title: RT‐LAMP for rapid diagnosis of coronavirus SARS‐CoV‐2
  publication-title: Microb Biotechnol
– start-page: 200343
  year: 2020
  article-title: Chest CT for typical 2019‐nCoV pneumonia: relationship to negative RT‐PCR testing
  publication-title: Radiology
– volume: 58
  start-page: e00557
  year: 2020
  end-page: e620
  article-title: Comparative performance of SARS‐CoV‐2 detection assays using seven different primer/probe sets and one assay kit
  publication-title: J Clin Microbiol
– volume: 27
  start-page: 609
  year: 2020
  end-page: 13
  article-title: Imaging features of coronavirus disease 2019 (COVID‐19): evaluation on thin‐section CT
  publication-title: Acad Radiol
– volume: 81
  year: 2020
  article-title: Saliva is a reliable tool to detect SARS‐CoV‐2
  publication-title: J Infect
– volume: 80
  start-page: e27
  year: 2020
  end-page: e28
  article-title: Multiple parameters required for diagnosis of COVID‐19 in clinical practice
  publication-title: J Infect
– year: 2020
  article-title: COVID‐19 diagnosis and management: a comprehensive review
  publication-title: J Intern Med.
– volume: 100
  start-page: 794
  year: 2020
  end-page: 800
  article-title: Retrospective analysis of laboratory testing in 54 patients with severe‐ or critical‐type 2019 novel coronavirus pneumonia
  publication-title: Lab Invest
– year: 2020
  article-title: Distinct characteristics of COVID‐19 patients with initial rRT‐PCR positive and negative results for SARS‐CoV‐2
  publication-title: Allergy
– year: 2020
  article-title: Imaging and clinical features of patients with 2019 novel coronavirus SARS‐CoV‐2: a systematic review and meta‐analysis
  publication-title: J Med Virol
– volume: 34
  start-page: 101623
  year: 2020
  article-title: Clinical, laboratory and imaging features of COVID‐19: a systematic review and meta‐analysis
  publication-title: Travel Med Infect Dis
– volume: 24
  start-page: 914
  year: 2017
  end-page: 9
  article-title: Adherence to standards for reporting diagnostic accuracy in emergency medicine research
  publication-title: Acad Emerg Med
– volume: 506
  start-page: 172
  year: 2020
  end-page: 5
  article-title: Dynamic change process of target genes by RT‐PCR testing of SARS‐Cov‐2 during the course of a coronavirus disease 2019 patient
  publication-title: Clin Chim Acta
– volume: 20
  start-page: 565
  year: 2020
  end-page: 74
  article-title: Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS‐CoV‐2: an observational cohort study
  publication-title: Lancet Infect Dis
– start-page: 201491
  year: 2020
  article-title: AI augmentation of radiologist performance in distinguishing COVID‐19 from pneumonia of other etiology on chest CT
  publication-title: Radiology
– volume: 295
  start-page: E8
  year: 2020
  article-title: Radiology department preparedness for COVID‐19: facing an unexpected outbreak of the disease
  publication-title: Radiology
– volume: 42
  start-page: 298
  year: 2003
  end-page: 303
  article-title: Emergency medicine/editorial. The problem with sensitivity and specificity
  publication-title: Ann Emerg Med
– volume: 105
  start-page: 154
  year: 2020
  end-page: 5
  article-title: Diagnosis of SARS‐CoV‐2 Infection based on CT scan vs. RT‐PCR: reflecting on experience from MERS‐CoV
  publication-title: J Hosp Infect
– volume: 8
  year: 2020
  article-title: Incidentally diagnosed COVID‐19 Infection in trauma patients; a clinical experience
  publication-title: Arch Acad Emerg Med
– volume: 23
  start-page: 272
  year: 2020
  end-page: 6
  article-title: Improved early recognition of coronavirus disease‐2019 (COVID‐19): single‐center data from a Shanghai screening hospital
  publication-title: Arch Iran Med
– year: 2020
  article-title: Use of radiographic features in COVID‐19 diagnosis: challenges and perspectives
  publication-title: J Chin Med Assoc
– volume: 2
  year: 2020
  article-title: Chest CT findings in cases from the cruise ship “Diamond Princess” with coronavirus disease 2019 (COVID‐19)
  publication-title: Radiol Cardiothorac Imaging
– volume: 105
  start-page: 1
  year: 2020
  end-page: 2
  article-title: Experience of different upper respiratory tract sampling strategies for detection of COVID‐19
  publication-title: J Hosp Infect
– volume: 38
  start-page: 400
  year: 2020
  end-page: 6
  article-title: Diagnostic performance of chest CT to differentiate COVID‐19 pneumonia in non‐high‐epidemic area in Japan
  publication-title: Jpn J Radiol
– volume: 296
  start-page: 172
  year: 2020
  end-page: 80
  article-title: The role of chest imaging in patient management during the COVID‐19 pandemic: a multinational consensus statement from the Fleischner Society
  publication-title: Chest
– volume: 149
  start-page: 816
  year: 2008
  end-page: 21
  article-title: When should a new test become the current reference standard?
  publication-title: Ann Intern Med
– volume: 127
  start-page: 104374
  year: 2020
  article-title: Interpret with caution: an evaluation of the commercial AusDiagnostics versus in‐house developed assays for the detection of SARS‐CoV‐2 virus
  publication-title: J Clin Virol
– volume: 7
  start-page: 001
  year: 2020
  end-page: 641
  article-title: Anosmia and dysgeusia in the absence of other respiratory diseases: should COVID‐19 infection be considered?
  publication-title: Eur J Case Rep Intern Med
– volume: 75
  start-page: 329
  year: 2020
  end-page: 34
  article-title: A British Society of Thoracic Imaging statement: considerations in designing local imaging diagnostic algorithms for the COVID‐19 pandemic
  publication-title: Clin Radiol
– volume: 323
  start-page: 2103
  year: 2020
  article-title: Masks and coronavirus disease 2019 (COVID‐19)
  publication-title: JAMA
– volume: 23
  start-page: 1325
  year: 2016
  end-page: 31
  article-title: State of the science: tools and measurement for shared decision making
  publication-title: Acad Emerg Med
– year: 2020
  article-title: Prediction for progression risk in patients with COVID‐19 pneumonia: the CALL score
  publication-title: Clin Infect Dis
– volume: 22
  start-page: 729
  year: 2020
  end-page: 35
  article-title: Development of reverse transcription loop‐mediated isothermal amplification assays targeting severe acute respiratory syndrom coronavirus 2 (SARS‐CoV‐2)
  publication-title: J Mol Diagn
– year: 2020
  article-title: Test performance evaluation of SARS‐CoV‐2 serological assays
  publication-title: medRxiv
– year: 2020
  article-title: Clinical and imaging features of COVID‐19
  publication-title: Radiol Infect Dis
– year: 2020
  article-title: A tool to early predict severe corona virus disease 2019 (COVID‐19): a multicenter study using the risk nomogram in Wuhan and Guangdong, China
  publication-title: Clin Infect Dis
– volume: 78
  start-page: 73
  year: 2016
  end-page: 82
  article-title: Partial verification bias and incorporation bias affected accuracy estimates of diagnostic studies for biomarkers that were part of an existing composite gold standard
  publication-title: J Clin Epidemiol
– volume: 126
  start-page: 108961
  year: 2020
  article-title: Diagnosis of the coronavirus disease (COVID‐19): rRT‐PCR or CT?
  publication-title: Eur J Radiol
– year: 2020
  article-title: Comparison of four molecular in vitro diagnostic assays for the detection of SARS‐CoV‐2 in nasopharyngeal specimens
  publication-title: J Clin Microbiol
– volume: 92
  start-page: 791
  year: 2020
  end-page: 6
  article-title: Diagnostic utility of clinical laboratory data determinations for patients with the severe COVID‐19
  publication-title: J Med Virol
– year: 2020
  article-title: Computed tomographic imaging of 3 patients with coronavirus disease 2019 pneumonia with negative virus real‐time reverse‐transcription polymerase chain reaction test
  publication-title: Clin Infect Dis
– volume: 323
  start-page: 1516
  year: 2020
  article-title: Stopping the spread of COVID‐19
  publication-title: JAMA
– volume: 95
  start-page: 1127
  year: 2020
  end-page: 9
  article-title: COVID‐19 testing: the threat of false‐negative results
  publication-title: Mayo Clin Proc
– volume: 84
  year: 2020
  article-title: The diagnostic and predictive role of NLR, d‐NLR and PLR in COVID‐19 patients
  publication-title: Int Immunopharmacol
– year: 2020
  article-title: Managing high clinical suspicion COVID‐19 inpatients with negative RT‐PCR: a pragmatic and limited role for thoracic CT
  publication-title: Thorax
– volume: 295
  start-page: 22
  year: 2020
  end-page: 3
  article-title: Use of chest CT in combination with negative RT‐PCR assay for the 2019 novel coronavirus but high clinical suspicion
  publication-title: Radiology
– year: 2020
  article-title: Radiological approach to COVID‐19 pneumonia with an emphasis on chest CT
  publication-title: Diagn Interv Radiol
– volume: 24
  start-page: 1030
  year: 2017
  end-page: 3
  article-title: Overcoming the Tower of Babel in medical science by finding the "EQUATOR": research reporting guidelines
  publication-title: Acad Emerg Med
– volume: 58
  start-page: 1095
  year: 2020
  end-page: 9
  article-title: Routine blood tests as a potential diagnostic tool for COVID‐19
  publication-title: Clin Chem Lab Med
– year: 2020
  article-title: Frequency and distribution of chest radiographic findings in COVID‐19 positive patients
  publication-title: Radiology
– volume: 27
  start-page: 461
  year: 2020
  end-page: 8
  article-title: Comparing rapid scoring systems in mortality prediction of critically ill patients with novel coronavirus disease
  publication-title: Acad Emerg Med
– year: 2020
  article-title: Profile of RT‐PCR for SARS‐CoV‐2: a preliminary study from 56 COVID‐19 patients
  publication-title: Clin Infect Dis
– volume: 42
  start-page: 1252
  year: 2020
  end-page: 8
  article-title: Objective evaluation of anosmia and ageusia in COVID‐19 patients: single‐center experience on 72 cases
  publication-title: Head Neck
– year: 2020
  article-title: Quantitative detection and viral load analysis of SARS‐CoV‐2 in infected patients
  publication-title: Clin Infect Dis
– volume: 215
  start-page: W19
  year: 2020
  article-title: Differential diagnosis for coronavirus disease (COVID‐ 19): beyond radiologic features
  publication-title: AJR Am J Roentgenol
– volume: 48
  start-page: 14
  year: 2020
  article-title: Coronavirus disease‐2019: is fever an adequate screening for the returning travelers?
  publication-title: Trop Med Health
– volume: 172
  start-page: 726
  year: 2020
  end-page: 34
  article-title: Diagnostic testing for severe acute respiratory syndrome‐related coronavirus‐2: a narrative review
  publication-title: Ann Intern Med
– volume: 26
  start-page: 948.e1
  year: 2020
  end-page: .e3
  article-title: Clinical characteristics of asymptomatic and symptomatic patients with mild COVID‐19
  publication-title: Clin Microbiol Infect
– volume: 2
  year: 2020
  article-title: Imaging profile of the COVID‐19 infection: radiologic findings and literature review
  publication-title: Radiol Cardiothorac Imaging
– year: 2020
  article-title: False‐negative of RT‐PCR and prolonged nucleic acid conversion in COVID‐19: rather than recurrence
  publication-title: J Med Virol
– volume: 133
  start-page: 1385
  year: 2020
  end-page: 6
  article-title: High‐throughput sequencing for confirmation of suspected 2019‐nCoV infection identified by fluorescence quantitative polymerase chain reaction
  publication-title: Chin Med J
– volume: 395
  start-page: 507
  year: 2020
  end-page: 13
  article-title: Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
  publication-title: Lancet
– volume: 92
  start-page: 538
  year: 2020
  end-page: 9
  article-title: Combination of RT‐qPCR testing and clinical features for diagnosis of COVID‐19 facilitates management of SARS‐CoV‐2 outbreak
  publication-title: J Med Virol
– volume: 94
  start-page: 107
  year: 2020
  end-page: 9
  article-title: Comparison of nasopharyngeal and oropharyngeal swabs for SARS‐CoV‐2 detection in 353 patients received tests with both specimens simultaneously
  publication-title: Int J Infect Dis
– year: 2020
  article-title: Comparison of Abbott ID Now, Diasorin Simplexa, and CDC FDA EUA methods for the detection of SARS‐CoV‐2 from nasopharyngeal and nasal swabs from individuals diagnosed with COVID‐19
  publication-title: J Clin Microbiol.
– volume: 127
  start-page: 104384
  year: 2020
  article-title: Comparing the analytical performance of three SARS‐CoV‐2 molecular diagnostic assays
  publication-title: J Clin Virol
– volume: 58
  start-page: 302
  year: 2020
  end-page: 3
  article-title: Anosmia as a prominent symptom of COVID‐19 infection
  publication-title: Rhinology
– volume: 14
  start-page: 317
  year: 2020
  end-page: 8
  article-title: Rapid sputum testing and not thermal screening alone should be the first‐line screening test at airports: a Bayesian analysis
  publication-title: Diabetes Metab Syndr
– start-page: 1
  year: 2020
  end-page: 4
  article-title: Chest CT and coronavirus disease (COVID‐19): a critical review of the literature to date
  publication-title: AJR Am J Roentgenol
– volume: 20
  year: 2020
  article-title: Do we know the diagnostic properties of the tests used in COVID‐19? A rapid review of recently published literature
  publication-title: Medwave
– year: 2020
  article-title: Features of anosmia in COVID‐19
  publication-title: Med Mal Infect
– volume: 6
  year: 2020
  article-title: Detection of SARS‐CoV‐2 RNA and antibodies in diverse samples: protocol to validate the sufficiency of provider‐observed home‐collected blood, saliva and oropharyngeal samples
  publication-title: JMIR Public Health Surveill.
– volume: 35
  year: 2020
  article-title: Clinical course and outcomes of patients with severe acute respiratory syndrome coronavirus 2 infection: a preliminary report of the first 28 patients from the Korean Cohort Study on COVID‐19
  publication-title: J Korean Med Sci
– volume: 20
  start-page: 1194
  year: 2013
  end-page: 206
  article-title: Understanding the direction of bias in studies of diagnostic test accuracy
  publication-title: Acad Emerg Med
– volume: 93
  start-page: 264
  year: 2020
  end-page: 7
  article-title: Comparison of different samples for 2019 novel coronavirus detection by nucleic acid amplification tests
  publication-title: Int J Infect Dis
– year: 2020
  article-title: A Bayesian analysis of strategies to rule out COVID19 using reverse transcriptase‐polymerase chain reaction (RT‐PCR)
  publication-title: Arch Pathol Lab Med
– volume: 20
  start-page: 453
  year: 2020
  end-page: 4
  article-title: Real‐time RT‐PCR in COVID‐19 detection: issues affecting the results
  publication-title: Expert Rev Mol Diagn
– volume: 44
  year: 2020
  article-title: AI‐driven tools for coronavirus outbreak: need of active learning and cross‐population train/test models on multitudinal/multimodal data
  publication-title: J Med Syst
– volume: 9
  start-page: 623
  year: 2020
  article-title: Potential rapid diagnostics, vaccine and therapeutics for 2019 novel coronavirus (2019‐nCoV): a systematic review
  publication-title: J Clin Med
– year: 2020
  article-title: Evaluation of COVID‐19 RT‐qPCR test in multi‐sample pools
  publication-title: Clin Infect Dis
– start-page: 139
  year: 2016
  end-page: 47
– year: 2020
  article-title: Clinical and epidemiological characteristics of 1,420 European patients with mild‐to‐moderate coronavirus disease 2019
  publication-title: J Intern Med
– volume: 20
  start-page: 411
  year: 2020
  end-page: 2
  article-title: Viral load of SARS‐CoV‐2 in clinical samples
  publication-title: Lancet Infect Dis
– start-page: 200432
  year: 2020
  article-title: Sensitivity of chest CT for COVID‐19: comparison to RT‐PCR
  publication-title: Radiology
– year: 2020
  article-title: A diagnostic model for coronavirus disease 2019 (COVID‐19) based on radiological semantic and clinical features: a multi‐center study
  publication-title: Eur Radiol
– year: 2020
  article-title: CT screening for early diagnosis of SARS‐CoV‐2 infection
  publication-title: Lancet Infect Dis
– volume: 150
  start-page: 47
  year: 2020
  end-page: 52
  article-title: A systematic scoping review of COVID‐19 during pregnancy and childbirth
  publication-title: Int J Gynaecol Obstet
– year: 2020
  article-title: Utility of hyposmia and hypogeusia for the diagnosis of COVID‐19
  publication-title: Lancet Infect Dis
– year: 2020
  article-title: CT screening for early diagnosis of SARS‐CoV‐2 infection ‐ authors' reply
  publication-title: Lancet Infect Dis
– volume: 38
  start-page: 409
  year: 2020
  end-page: 10
  article-title: A case report of COVID‐19 with false negative RT‐PCR test: necessity of chest CT
  publication-title: Jpn J Radiol
– start-page: 200823
  year: 2020
  article-title: Performance of radiologists in differentiating COVID‐19 from viral pneumonia on chest CT
  publication-title: Radiology
– year: 2020
  article-title: COVID‐19 antibody seroprevalence in Santa Clara County, California
  publication-title: medRxIV
– volume: 58
  start-page: 1089
  year: 2020
  end-page: 94
  article-title: Comparison of throat swabs and sputum specimens for viral nucleic acid detection in 52 cases of novel coronavirus (SARS‐Cov‐2)‐infected pneumonia (COVID‐19)
  publication-title: Clin Chem Lab Med
– volume: 23
  start-page: 768
  year: 2008
  end-page: 74
  article-title: The STARD statement for reporting diagnostic accuracy studies: application to the history and physical examination
  publication-title: J Gen Intern Med
– year: 2020
  article-title: Initial clinical features of suspected coronavirus disease 2019 in two emergency departments outside of Hubei, China
  publication-title: J Med Virol
– year: 2020
  article-title: Chest CT in patients suspected of COVID‐19 infection: a reliable alternative for RT‐PCR
  publication-title: Am J Emerg Med
– start-page: 54
  year: 2013
  end-page: 64
– volume: 169
  start-page: 476
  year: 2018
  end-page: 3
  article-title: PRISMA extension for scoping reviews (PRISMA‐ScR): checklist and explanation
  publication-title: Ann Intern Med
– volume: 163
  start-page: 132
  year: 2020
  end-page: 34
  article-title: COVID‐19 anosmia reporting tool: initial findings
  publication-title: Otolaryngol Head Neck Surg
– year: 2020
  article-title: PCR Assays turned positive in 25 discharged COVID‐19 patients
  publication-title: Clin Infect Dis
– volume: 185
  start-page: E537
  year: 2013
  end-page: E544
  article-title: Variation of a test's sensitivity and specificity with disease prevalence
  publication-title: CMAJ
– volume: 9
  start-page: 998
  year: 2020
  end-page: 1007
  article-title: Development of a reverse transcription‐loop‐mediated isothermal amplification as a rapid early‐detection method for novel SARS‐CoV‐2
  publication-title: Emerg Microbes Infect
– volume: 351
  start-page: h5527
  year: 2015
  article-title: STARD 2015: an updated list of essential items for reporting diagnostic accuracy studies
  publication-title: BMJ
– start-page: 343
  year: 2009
  end-page: 54
– volume: 2
  year: 2020
  article-title: Cautions about radiologic diagnosis of COVID‐19 infection driven by artificial intelligence
  publication-title: Lancet Digital Health
– volume: 33
  start-page: 575
  year: 1999
  end-page: 80
  article-title: Likelihood ratio: A powerful tool for incorporating the results of a diagnostic test into clinical decisionmaking
  publication-title: Annals of Emergency Medicine
– year: 2020
  article-title: Application and optimization of RT‐PCR in diagnosis of SARS‐CoV‐2 infection
  publication-title: medRxiv
– year: 2020
  article-title: Smell and taste symptom‐based predictive model for COVID‐19 diagnosis
  publication-title: Int Forum Allergy Rhinol
– volume: 51
  start-page: 450
  year: 2020
  end-page: 2
  article-title: Global threat of SARS‐CoV‐2/COVID‐19 and the need for more and better diagnostic tools
  publication-title: Arch Med Res
– year: 2020
  article-title: Clinical evaluation of three sample‐to‐answer platforms for the detection of SARS‐CoV‐2
  publication-title: J Clin Microbiol
– volume: 369
  start-page: m1328
  year: 2020
  article-title: Prediction models for diagnosis and prognosis of covid‐19 infection: systematic review and critical appraisal
  publication-title: BMJ
– volume: 21
  start-page: 184
  year: 2020
  end-page: 90
  article-title: 2019‐nCoV: the identify‐isolate‐inform (3I) tool applied to a novel emerging coronavirus
  publication-title: West J Emerg Med
– volume: 17
  start-page: 2725
  year: 2020
  end-page: 40
  article-title: Effect of delay in diagnosis on transmission of COVID‐19
  publication-title: Math Biosci Eng
– volume: 2
  start-page: 69
  year: 2011
  end-page: 77
  article-title: A systematic review of clinical decision rules for the diagnosis of influenza
  publication-title: Ann Fam Med
– volume: 80
  start-page: 671
  year: 2020
  end-page: 93
  article-title: Clinical features of atypical 2019 novel coronavirus pneumonia with an initially negative RT‐PCR assay
  publication-title: J Infect
– volume: 155
  start-page: 529
  year: 2011
  end-page: 36
  article-title: QUADAS‐2: a revised tool for the quality assessment of diagnostic accuracy studies
  publication-title: Ann Intern Med
– year: 2020
– volume: 369
  start-page: m1403
  year: 2020
  article-title: Covid‐19: testing times
  publication-title: BMJ
– volume: 5
  year: 2020
  article-title: The laboratory tests and host immunity of COVID‐19 patients with different severity of illness
  publication-title: JCI Insight
– volume: 42
  start-page: 292
  year: 2003
  end-page: 7
  article-title: Interval likelihood ratios: Another advantage for the evidence‐based diagnostician
  publication-title: Annals of Emergency Medicine
– volume: 8
  year: 2020
  article-title: Laboratory parameters in detection of COVID‐19 patients with positive RT‐PCR; a diagnostic accuracy study
  publication-title: Arch Acad Emerg Med
– year: 2020
  article-title: The promise and perils of antibody testing for COVID‐19
  publication-title: JAMA
– ident: e_1_2_8_49_1
  doi: 10.1111/all.14316
– ident: e_1_2_8_115_1
  doi: 10.7326/0003-4819-149-11-200812020-00009
– ident: e_1_2_8_21_1
  doi: 10.1016/j.medmal.2020.04.006
– ident: e_1_2_8_130_1
  doi: 10.1001/jama.2020.6437
– ident: e_1_2_8_16_1
  doi: 10.1016/S1473-3099(20)30297-8
– ident: e_1_2_8_122_1
  doi: 10.1111/acem.13225
– ident: e_1_2_8_56_1
  doi: 10.1016/j.jhin.2020.03.012
– ident: e_1_2_8_36_1
  doi: 10.1016/j.arcmed.2020.04.003
– ident: e_1_2_8_81_1
  doi: 10.1016/S0140-6736(20)30211-7
– volume: 7
  start-page: 001
  year: 2020
  ident: e_1_2_8_26_1
  article-title: Anosmia and dysgeusia in the absence of other respiratory diseases: should COVID‐19 infection be considered?
  publication-title: Eur J Case Rep Intern Med
– ident: e_1_2_8_112_1
– ident: e_1_2_8_45_1
  doi: 10.1002/jmv.25855
– ident: e_1_2_8_6_1
  doi: 10.7326/M18-0850
– ident: e_1_2_8_35_1
  doi: 10.1136/bmj.m1403
– ident: e_1_2_8_113_1
  doi: 10.1016/j.jclinepi.2016.03.022
– ident: e_1_2_8_63_1
  doi: 10.1093/cid/ciaa345
– ident: e_1_2_8_7_1
  doi: 10.7326/M20-1301
– ident: e_1_2_8_40_1
  doi: 10.1128/JCM.00743-20
– ident: e_1_2_8_22_1
  doi: 10.1016/j.cmi.2020.04.040
– ident: e_1_2_8_107_1
  doi: 10.3934/mbe.2020149
– ident: e_1_2_8_126_1
  doi: 10.1093/cid/ciaa414
– ident: e_1_2_8_59_1
  doi: 10.2196/19054
– ident: e_1_2_8_98_1
  doi: 10.1148/radiol.2020200432
– ident: e_1_2_8_72_1
– year: 2020
  ident: e_1_2_8_103_1
  article-title: COVID‐19 antibody seroprevalence in Santa Clara County, California
  publication-title: medRxIV
– ident: e_1_2_8_97_1
  doi: 10.1016/S2589-7500(20)30079-0
– ident: e_1_2_8_4_1
  doi: 10.1016/j.mayocp.2020.04.004
– ident: e_1_2_8_14_1
  doi: 10.34172/aim.2020.10
– ident: e_1_2_8_92_1
  doi: 10.1016/j.jhin.2020.03.001
– ident: e_1_2_8_73_1
– ident: e_1_2_8_30_1
  doi: 10.1016/j.intimp.2020.106504
– ident: e_1_2_8_127_1
  doi: 10.1093/cid/ciaa443
– ident: e_1_2_8_135_1
  doi: 10.5867/medwave.2020.03.7891
– ident: e_1_2_8_13_1
  doi: 10.1016/j.tmaid.2020.101623
– ident: e_1_2_8_37_1
  doi: 10.1093/cid/ciaa531
– ident: e_1_2_8_65_1
  doi: 10.1067/mem.2003.273
– ident: e_1_2_8_109_1
  doi: 10.1148/radiol.2020201214
– ident: e_1_2_8_78_1
  doi: 10.1016/j.acra.2020.03.002
– ident: e_1_2_8_28_1
  doi: 10.5152/dir.2020.20231
– ident: e_1_2_8_46_1
  doi: 10.1093/cid/ciaa398
– ident: e_1_2_8_48_1
  doi: 10.5858/arpa.2020-0196-LE
– ident: e_1_2_8_10_1
  doi: 10.1111/acem.12255
– start-page: 54
  volume-title: Evidence‐Based Emergency Care: Diagnostic Testing and Clinical Decision Rules
  year: 2013
  ident: e_1_2_8_116_1
– ident: e_1_2_8_41_1
  doi: 10.1128/JCM.00783-20
– ident: e_1_2_8_120_1
  doi: 10.1148/ryct.2020200110
– ident: e_1_2_8_62_1
  doi: 10.1016/S1473-3099(20)30113-4
– ident: e_1_2_8_86_1
  doi: 10.1148/radiol.2020200330
– ident: e_1_2_8_51_1
  doi: 10.1093/clinchem/hvaa099
– ident: e_1_2_8_124_1
  doi: 10.1111/j.1538-7836.2008.02944.x
– ident: e_1_2_8_129_1
  doi: 10.1067/mem.2003.274
– ident: e_1_2_8_5_1
  doi: 10.1515/cclm-2020-0240
– ident: e_1_2_8_11_1
  doi: 10.1002/jmv.25822
– ident: e_1_2_8_61_1
  doi: 10.1515/cclm-2020-0187
– ident: e_1_2_8_88_1
  doi: 10.1093/cid/ciaa207
– ident: e_1_2_8_29_1
  doi: 10.1515/cclm-2020-0398
– ident: e_1_2_8_58_1
  doi: 10.1007/s10916-020-01562-1
– ident: e_1_2_8_90_1
  doi: 10.1007/s00330-020-06829-2
– ident: e_1_2_8_83_1
  doi: 10.2214/AJR.20.23202
– ident: e_1_2_8_93_1
  doi: 10.1016/j.ajem.2020.04.016
– ident: e_1_2_8_18_1
  doi: 10.4193/Rhin20.140
– ident: e_1_2_8_24_1
  doi: 10.1370/afm.1192
– volume: 8
  year: 2020
  ident: e_1_2_8_31_1
  article-title: Laboratory parameters in detection of COVID‐19 patients with positive RT‐PCR; a diagnostic accuracy study
  publication-title: Arch Acad Emerg Med
– ident: e_1_2_8_53_1
  doi: 10.1128/JCM.00760-20
– ident: e_1_2_8_131_1
  doi: 10.1001/jama.2020.4269
– ident: e_1_2_8_87_1
  doi: 10.1148/radiol.2020200343
– ident: e_1_2_8_20_1
  doi: 10.1002/hed.26204
– ident: e_1_2_8_32_1
  doi: 10.1172/jci.insight.137799
– ident: e_1_2_8_77_1
  doi: 10.1148/radiol.2020201160
– ident: e_1_2_8_3_1
– ident: e_1_2_8_70_1
  doi: 10.1016/j.jmoldx.2020.03.006
– ident: e_1_2_8_125_1
  doi: 10.1136/bmj.m1328
– year: 2020
  ident: e_1_2_8_76_1
  article-title: Use of radiographic features in COVID‐19 diagnosis: challenges and perspectives
  publication-title: J Chin Med Assoc
– ident: e_1_2_8_66_1
  doi: 10.1016/S0196-0644(99)70346-X
– ident: e_1_2_8_94_1
  doi: 10.1016/S1473-3099(20)30241-3
– ident: e_1_2_8_128_1
  doi: 10.1111/acem.13992
– ident: e_1_2_8_136_1
  doi: 10.1002/ijgo.13182
– ident: e_1_2_8_119_1
  doi: 10.1503/cmaj.121286
– ident: e_1_2_8_101_1
  doi: 10.1136/thoraxjnl-2020-214916
– ident: e_1_2_8_23_1
  doi: 10.1111/joim.13089
– ident: e_1_2_8_117_1
  doi: 10.1093/cid/ciaa460
– ident: e_1_2_8_50_1
  doi: 10.1080/14737159.2020.1757437
– ident: e_1_2_8_9_1
  doi: 10.1007/s11606-008-0583-3
– ident: e_1_2_8_52_1
  doi: 10.1002/jmv.25721
– ident: e_1_2_8_82_1
  doi: 10.1007/s11604-020-00958-w
– ident: e_1_2_8_54_1
  doi: 10.1128/JCM.00557-20
– year: 2020
  ident: e_1_2_8_102_1
  article-title: Test performance evaluation of SARS‐CoV‐2 serological assays
  publication-title: medRxiv
– ident: e_1_2_8_132_1
  doi: 10.1111/acem.13071
– ident: e_1_2_8_121_1
  doi: 10.1111/acem.13233
– volume: 35
  year: 2020
  ident: e_1_2_8_79_1
  article-title: Clinical course and outcomes of patients with severe acute respiratory syndrome coronavirus 2 infection: a preliminary report of the first 28 patients from the Korean Cohort Study on COVID‐19
  publication-title: J Korean Med Sci
– ident: e_1_2_8_27_1
  doi: 10.1002/alr.22602
– ident: e_1_2_8_85_1
  doi: 10.1016/j.jinf.2020.02.008
– ident: e_1_2_8_89_1
  doi: 10.1016/S1473-3099(20)30247-4
– ident: e_1_2_8_2_1
  doi: 10.2214/AJR.20.23119
– ident: e_1_2_8_91_1
  doi: 10.1007/s11604-020-00967-9
– ident: e_1_2_8_44_1
  doi: 10.1016/j.cca.2020.03.032
– start-page: 343
  volume-title: The Rational Clinical Examination: Evidence‐Based Clinical Diagnosis
  year: 2009
  ident: e_1_2_8_25_1
– ident: e_1_2_8_137_1
– ident: e_1_2_8_38_1
  doi: 10.1093/ajcp/aqaa064
– ident: e_1_2_8_96_1
  doi: 10.1148/radiol.2020201491
– ident: e_1_2_8_106_1
– ident: e_1_2_8_114_1
  doi: 10.1016/j.jinf.2020.03.016
– ident: e_1_2_8_133_1
  doi: 10.1111/joim.13091
– ident: e_1_2_8_33_1
  doi: 10.1002/jmv.25770
– ident: e_1_2_8_60_1
  doi: 10.1016/j.jinf.2020.04.005
– ident: e_1_2_8_118_1
  doi: 10.1016/S1473-3099(20)30196-1
– ident: e_1_2_8_80_1
  doi: 10.1148/ryct.2020200034
– ident: e_1_2_8_34_1
  doi: 10.1038/s41374-020-0431-6
– ident: e_1_2_8_15_1
  doi: 10.1186/s41182-020-00201-2
– ident: e_1_2_8_74_1
– ident: e_1_2_8_105_1
  doi: 10.15557/PiMR.2020.0024
– ident: e_1_2_8_55_1
– ident: e_1_2_8_68_1
  doi: 10.1080/22221751.2020.1756698
– ident: e_1_2_8_108_1
  doi: 10.5811/westjem.2020.1.46760
– ident: e_1_2_8_67_1
  doi: 10.1016/j.ijid.2020.02.050
– start-page: 139
  volume-title: Doing Research in Emergency and Acute Care: Making Order Out of Chaos
  year: 2016
  ident: e_1_2_8_123_1
– ident: e_1_2_8_64_1
  doi: 10.1016/j.dsx.2020.03.015
– ident: e_1_2_8_57_1
  doi: 10.1016/j.ijid.2020.04.023
– year: 2020
  ident: e_1_2_8_104_1
  article-title: The promise and perils of antibody testing for COVID‐19
  publication-title: JAMA
– ident: e_1_2_8_110_1
  doi: 10.1016/j.jrid.2020.04.003
– ident: e_1_2_8_100_1
  doi: 10.1016/j.crad.2020.03.008
– ident: e_1_2_8_69_1
  doi: 10.1111/1751-7915.13586
– ident: e_1_2_8_99_1
  doi: 10.1016/j.ejrad.2020.108961
– ident: e_1_2_8_138_1
  doi: 10.7326/0003-4819-155-8-201110180-00009
– ident: e_1_2_8_134_1
  doi: 10.1001/jamahealthforum.2020.0448
– ident: e_1_2_8_71_1
  doi: 10.1097/CM9.0000000000000792
– ident: e_1_2_8_42_1
  doi: 10.3390/jcm9030623
– ident: e_1_2_8_75_1
  doi: 10.5152/dir.2020.20260
– ident: e_1_2_8_95_1
  doi: 10.1148/radiol.2020200823
– volume: 8
  year: 2020
  ident: e_1_2_8_84_1
  article-title: Incidentally diagnosed COVID‐19 Infection in trauma patients; a clinical experience
  publication-title: Arch Acad Emerg Med
– volume: 296
  start-page: 172
  year: 2020
  ident: e_1_2_8_111_1
  article-title: The role of chest imaging in patient management during the COVID‐19 pandemic: a multinational consensus statement from the Fleischner Society
  publication-title: Chest
– ident: e_1_2_8_17_1
  doi: 10.1111/ene.14273
– ident: e_1_2_8_43_1
  doi: 10.1016/j.jcv.2020.104374
– ident: e_1_2_8_12_1
  doi: 10.1002/jmv.25763
– ident: e_1_2_8_19_1
  doi: 10.1177/0194599820922992
– year: 2020
  ident: e_1_2_8_47_1
  article-title: Application and optimization of RT‐PCR in diagnosis of SARS‐CoV‐2 infection
  publication-title: medRxiv
– ident: e_1_2_8_8_1
  doi: 10.1136/bmj.h5527
– ident: e_1_2_8_39_1
  doi: 10.1016/j.jcv.2020.104384
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Snippet Objective Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) emerged as a global pandemic in early 2020 with rapidly evolving approaches to...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged as a global pandemic in early 2020 with rapidly evolving approaches to diagnosing the...
ObjectiveSevere acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) emerged as a global pandemic in early 2020 with rapidly evolving approaches to diagnosing...
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wiley
SourceType Open Access Repository
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StartPage 653
SubjectTerms Accuracy
Adult
Coronaviruses
COVID-19 - diagnosis
COVID-19 Testing - statistics & numerical data
Diagnostic Tests, Routine
Editors' Pick
Emergency Service, Hospital
Evidence‐Based Diagnostics
Female
Humans
Laboratories
Medical diagnosis
Pandemics - statistics & numerical data
Physical Examination - statistics & numerical data
SARS-CoV-2 - isolation & purification
Serology
Severe acute respiratory syndrome coronavirus 2
Tomography, X-Ray Computed
Title Diagnosing COVID‐19 in the Emergency Department: A Scoping Review of Clinical Examinations, Laboratory Tests, Imaging Accuracy, and Biases
URI https://onlinelibrary.wiley.com/doi/abs/10.1111%2Facem.14048
https://www.ncbi.nlm.nih.gov/pubmed/32542934
https://www.proquest.com/docview/2437709886
https://www.proquest.com/docview/2414009527
https://pubmed.ncbi.nlm.nih.gov/PMC7323136
Volume 27
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