Assessment of contact predictions in CASP12: Co‐evolution and deep learning coming of age

Following up on the encouraging results of residue‐residue contact prediction in the CASP11 experiment, we present the analysis of predictions submitted for CASP12. The submissions include predictions of 34 groups for 38 domains classified as free modeling targets which are not accessible to homolog...

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Veröffentlicht in:	Proteins, structure, function, and bioinformatics Jg. 86; H. S1; S. 51 - 66
Hauptverfasser:	Schaarschmidt, Joerg, Monastyrskyy, Bohdan, Kryshtafovych, Andriy, Bonvin, Alexandre M.J.J.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Wiley Subscription Services, Inc 01.03.2018 John Wiley and Sons Inc
Schlagworte:	Accessibility Algorithms CASP Coevolution Computational Biology - methods contact prediction correlated mutations co‐variation Crystallography, X-Ray Databases, Protein de novo structure prediction Deep learning evolutionary coupling Homology Humans Learning algorithms Machine Learning Mathematical models Modelling Models, Molecular Protein Conformation Protein Folding Protein Interaction Domains and Motifs Proteins - chemistry Software Ultrasonic testing co-variation de novo structure prediction contact prediction CASP correlated mutations evolutionary coupling
ISSN:	0887-3585, 1097-0134, 1097-0134
Online-Zugang:	Volltext
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