Urethral luminal epithelia are castration‐insensitive cells of the proximal prostate

Background Castration‐insensitive epithelial progenitors capable of regenerating the prostate have been proposed to be concentrated in the proximal region based on facultative assays. Functional characterization of prostate epithelial populations isolated with individual cell surface markers has fai...

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Bibliographic Details
Published in:	The Prostate Vol. 80; no. 11; pp. 872 - 884
Main Authors:	Joseph, Diya B., Henry, Gervaise H., Malewska, Alicia, Iqbal, Nida S., Ruetten, Hannah M., Turco, Anne E., Abler, Lisa L., Sandhu, Simran K., Cadena, Mark T., Malladi, Venkat S., Reese, Jeffrey C., Mauck, Ryan J., Gahan, Jeffrey C., Hutchinson, Ryan C., Roehrborn, Claus G., Baker, Linda A., Vezina, Chad M., Strand, Douglas W.
Format:	Journal Article
Language:	English
Published:	United States Wiley Subscription Services, Inc 01.08.2020
Subjects:	Adolescent Adult Animals Antigens, Neoplasm - metabolism benign prostatic hyperplasia Castration Cell Adhesion Molecules - metabolism Cell surface Embryos Epithelial cells Epithelial Cells - cytology Epithelial Cells - metabolism Etiology Flow cytometry Humans Hyperplasia Male Mice Mice, Inbred C57BL Nodules Prostate Prostate - cytology Prostate - metabolism prostate stem cell prostatic urethra Reductase Ribonucleic acid RNA single‐cell RNA sequencing Stem Cells - cytology Stem Cells - metabolism Surface markers Transcription Transcriptomics Urethra Urethra - cytology Urethra - metabolism Young Adult single-cell RNA sequencing prostatic urethra prostate stem cell castration benign prostatic hyperplasia
ISSN:	0270-4137, 1097-0045, 1097-0045
Online Access:	Get full text
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