Splicing factor mutations in hematologic malignancies

Mutations in genes encoding RNA splicing factors were discovered nearly 10 years ago and are now understood to be among the most recurrent genetic abnormalities in patients with all forms of myeloid neoplasms and several types of lymphoproliferative disorders, as well as subjects with clonal hematop...

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Vydáno v:	Blood Ročník 138; číslo 8; s. 599
Hlavní autoři:	Chen, Sisi, Benbarche, Salima, Abdel-Wahab, Omar
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 26.08.2021
Témata:	Cell Transformation, Neoplastic - genetics Cell Transformation, Neoplastic - metabolism Cell Transformation, Neoplastic - pathology Hematologic Neoplasms - genetics Hematologic Neoplasms - metabolism Hematologic Neoplasms - pathology Hematopoiesis - genetics Humans Mutation Neoplasm Proteins - genetics Neoplasm Proteins - metabolism RNA Splicing RNA Splicing Factors - genetics RNA Splicing Factors - metabolism RNA, Messenger - biosynthesis RNA, Messenger - genetics RNA, Neoplasm - biosynthesis RNA, Neoplasm - genetics
ISSN:	1528-0020, 1528-0020
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