The role of plasminogen activators in stroke treatment: fibrinolysis and beyond

Although recent technical advances in thrombectomy have revolutionised acute stroke treatment, prevalence of disability and death related to stroke remain high. Therefore, plasminogen activators—eukaryotic, bacterial, or engineered forms that can promote fibrinolysis by converting plasminogen into a...

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Bibliographic Details

Published in:	Lancet neurology Vol. 17; no. 12; pp. 1121 - 1132
Main Authors:	Thiebaut, Audrey M, Gauberti, Maxime, Ali, Carine, Martinez De Lizarrondo, Sara, Vivien, Denis, Yepes, Manuel, Roussel, Benoit D
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.12.2018 Elsevier Limited
Subjects:	Arteries Brain Fibrin Fibrinolysis Hematoma Neurotoxicity Physiology Plasmin Proteins Stroke Therapeutic applications
ISSN:	1474-4422, 1474-4465, 1474-4465
Online Access:	Get full text
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