Genome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite infection

Rhodnius prolixus not only has served as a model organism for the study of insect physiology, but also is a major vector of Chagas disease, an illness that affects approximately seven million people worldwide. We sequenced the genome of R. prolixus, generated assembled sequences covering 95% of the...

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Published in:	Proceedings of the National Academy of Sciences - PNAS Vol. 112; no. 48; p. 14936
Main Authors:	Mesquita, Rafael D, Vionette-Amaral, Raquel J, Lowenberger, Carl, Rivera-Pomar, Rolando, Monteiro, Fernando A, Minx, Patrick, Spieth, John, Carvalho, A Bernardo, Panzera, Francisco, Lawson, Daniel, Torres, André Q, Ribeiro, Jose M C, Sorgine, Marcos H F, Waterhouse, Robert M, Montague, Michael J, Abad-Franch, Fernando, Alves-Bezerra, Michele, Amaral, Laurence R, Araujo, Helena M, Araujo, Ricardo N, Aravind, L, Atella, Georgia C, Azambuja, Patricia, Berni, Mateus, Bittencourt-Cunha, Paula R, Braz, Gloria R C, Calderón-Fernández, Gustavo, Carareto, Claudia M A, Christensen, Mikkel B, Costa, Igor R, Costa, Samara G, Dansa, Marilvia, Daumas-Filho, Carlos R O, De-Paula, Iron F, Dias, Felipe A, Dimopoulos, George, Emrich, Scott J, Esponda-Behrens, Natalia, Fampa, Patricia, Fernandez-Medina, Rita D, da Fonseca, Rodrigo N, Fontenele, Marcio, Fronick, Catrina, Fulton, Lucinda A, Gandara, Ana Caroline, Garcia, Eloi S, Genta, Fernando A, Giraldo-Calderón, Gloria I, Gomes, Bruno, Gondim, Katia C, Granzotto, Adriana, Guarneri, Alessandra A, Guigó, Roderic, Harry, Myriam, Hughes, Daniel S T, Jablonka, Willy, Jacquin-Joly, Emmanuelle, Juárez, M Patricia, Koerich, Leonardo B, Lange, Angela B, Latorre-Estivalis, José Manuel, Lavore, Andrés, Lawrence, Gena G, Lazoski, Cristiano, Lazzari, Claudio R, Lopes, Raphael R, Lorenzo, Marcelo G, Lugon, Magda D, Majerowicz, David, Marcet, Paula L, Mariotti, Marco, Masuda, Hatisaburo, Megy, Karine, Melo, Ana C A, Missirlis, Fanis, Mota, Theo, Noriega, Fernando G, Nouzova, Marcela, Nunes, Rodrigo D, Oliveira, Raquel L L, Oliveira-Silveira, Gilbert, Ons, Sheila, Orchard, Ian, Pagola, Lucia, Paiva-Silva, Gabriela O, Pascual, Agustina, Pavan, Marcio G, Pedrini, Nicolás, Peixoto, Alexandre A, Pereira, Marcos H, Pike, Andrew, Polycarpo, Carla, Prosdocimi, Francisco, Ribeiro-Rodrigues, Rodrigo, Robertson, Hugh M, Salerno, Ana Paula, Salmon, Didier, Santesmasses, Didac, Schama, Renata, Seabra-Junior, Eloy S
Format:	Journal Article
Language:	English
Published:	United States 01.12.2015
Subjects:	Adaptation, Physiological - genetics Animals Base Sequence Chagas Disease Gene Transfer, Horizontal Host-Parasite Interactions - genetics Humans Insect Vectors - genetics Insect Vectors - parasitology Molecular Sequence Data Rhodnius - genetics Rhodnius - parasitology Trypanosoma cruzi - physiology Wolbachia - genetics hematophagy Chagas disease genome Rhodnius prolixus immunity
ISSN:	1091-6490, 1091-6490
Online Access:	Get more information
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