Nitrofurantoin resistance mechanism and fitness cost in Escherichia coli

The biological fitness cost of antibiotic resistance is a key parameter in determining the rate of appearance and spread of antibiotic-resistant bacteria. We identified mutations conferring nitrofurantoin resistance and examined their effect on the fitness of clinical Escherichia coli isolates. By p...

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Vydané v:	Journal of antimicrobial chemotherapy Ročník 62; číslo 3; s. 495
Hlavní autori:	Sandegren, Linus, Lindqvist, Anton, Kahlmeter, Gunnar, Andersson, Dan I
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England 01.09.2008
Predmet:	Anti-Infective Agents, Urinary - pharmacology DNA Mutational Analysis Drug Resistance, Bacterial Escherichia coli - drug effects Escherichia coli - genetics Escherichia coli - growth & development Escherichia coli - isolation & purification Escherichia coli Infections - microbiology Escherichia coli Proteins - genetics Humans Microbial Sensitivity Tests Microbial Viability Mutation Nitrofurantoin - pharmacology Nitroreductases - genetics Women
ISSN:	1460-2091, 1460-2091
On-line prístup:	Zistit podrobnosti o prístupe
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