Activated protein C has a regulatory role in factor VIII function

Mechanisms thought to regulate activated factor VIII (FVIIIa) cofactor function include A2-domain dissociation and activated protein C (APC) cleavage. Unlike A2-domain dissociation, there is no known phenotype associated with altered APC cleavage of FVIII, and biochemical studies have suggested APC...

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Vydané v:	Blood Ročník 137; číslo 18; s. 2532
Hlavní autori:	Wilhelm, Amelia R, Parsons, Nicole A, Samelson-Jones, Benjamin J, Davidson, Robert J, Esmon, Charles T, Camire, Rodney M, George, Lindsey A
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 06.05.2021
ISSN:	1528-0020, 1528-0020
On-line prístup:	Zistit podrobnosti o prístupe
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