Fusobacterium nucleatum adhesin FadA binds vascular endothelial cadherin and alters endothelial integrity

Summary Fusobacterium nucleatum is a Gram‐negative oral anaerobe, capable of systemic dissemination causing infections and abscesses, often in mixed‐species, at different body sites. We have shown previously that F. nucleatum adheres to and invades host epithelial and endothelial cells via a novel F...

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Veröffentlicht in:	Molecular microbiology Jg. 82; H. 6; S. 1468 - 1480
Hauptverfasser:	Fardini, Yann, Wang, Xiaowei, Témoin, Stéphanie, Nithianantham, Stanley, Lee, David, Shoham, Menachem, Han, Yiping W.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Oxford, UK Blackwell Publishing Ltd 01.12.2011 Blackwell
Schlagworte:	Adhesins, Bacterial - chemistry Adhesins, Bacterial - genetics Adhesins, Bacterial - metabolism Amino Acid Motifs Antigens, CD - genetics Antigens, CD - metabolism Bacteria Binding sites Biological and medical sciences Blood-Brain Barrier - metabolism Blood-Brain Barrier - microbiology Cadherins - genetics Cadherins - metabolism Cell adhesion & migration Cells E coli Endothelial Cells - metabolism Endothelial Cells - microbiology Escherichia coli Fundamental and applied biological sciences. Psychology Fusobacterium Infections - metabolism Fusobacterium Infections - microbiology Fusobacterium nucleatum Fusobacterium nucleatum - chemistry Fusobacterium nucleatum - genetics Fusobacterium nucleatum - metabolism Gram-negative bacteria Humans Microbiology Microorganisms Protein Binding Relocation Bacteria Adhesin Fusobacterium nucleatum Cadherin Cell adhesion molecule Bacteroidaceae
ISSN:	0950-382X, 1365-2958, 1365-2958
Online-Zugang:	Volltext
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