PI3K/AKT pathway as a key link modulates the multidrug resistance of cancers

Multidrug resistance (MDR) is the dominant challenge in the failure of chemotherapy in cancers. Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that spreads intracellular signal cascades and regulates a variety of cellular processes. PI3Ks are considered significant causes of chemoresistance...

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Veröffentlicht in:	Cell death & disease Jg. 11; H. 9; S. 797
Hauptverfasser:	Liu, Rui, Chen, Youwen, Liu, Guangzhi, Li, Chenxi, Song, Yurong, Cao, Zhiwen, Li, Wen, Hu, Jinghong, Lu, Cheng, Liu, Yuanyan
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 24.09.2020
Schlagworte:	631/67/1059/602 631/67/2327 Antibodies Biochemistry Biomedical and Life Sciences Cell Biology Cell Culture Cell Proliferation Drug Resistance, Multiple - genetics Humans Immunology Life Sciences Neoplasms - drug therapy Neoplasms - genetics Proto-Oncogene Proteins c-akt - metabolism Review Review Article Signal Transduction
ISSN:	2041-4889, 2041-4889
Online-Zugang:	Volltext
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