Surgical Stress Increases Circulating Low-Density Neutrophils Which May Promote Tumor Recurrence

Low-density neutrophils (LDN) have been shown to be increased in peripheral blood in patients with various diseases and closely related to immune-mediated pathology. However, the frequency and function of LDN in circulating blood of the patients following abdominal surgery have not been well underst...

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Bibliographic Details
Published in:	The Journal of surgical research Vol. 246; pp. 52 - 61
Main Authors:	Kumagai, Yuko, Ohzawa, Hideyuki, Miyato, Hideyo, Horie, Hisanaga, Hosoya, Yoshinori, Lefor, Alan Kawarai, Sata, Naohiro, Kitayama, Joji
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01.02.2020
Subjects:	Antigens, CD - immunology Antigens, CD - metabolism Blood Loss, Surgical - statistics & numerical data Cell Adhesion Molecules - immunology Cell Adhesion Molecules - metabolism Cell Communication - immunology Cell Line, Tumor Cell Proliferation Coculture Techniques Digestive System Surgical Procedures - adverse effects Extracellular Traps - immunology Extracellular Traps - metabolism Gastrointestinal Neoplasms - immunology Gastrointestinal Neoplasms - pathology Gastrointestinal Neoplasms - surgery GPI-Linked Proteins - immunology GPI-Linked Proteins - metabolism Humans Immunosuppression Leukocyte Count Low-density neutrophils Neoplasm Recurrence, Local - epidemiology Neoplasm Recurrence, Local - immunology Neoplastic Cells, Circulating - immunology Neutrophil extracellular traps Neutrophils - immunology Neutrophils - metabolism Operative Time Stress, Physiological - immunology Surgical stress T-Lymphocytes - immunology Low-density neutrophils Surgical stress Immunosuppression Neutrophil extracellular traps
ISSN:	0022-4804, 1095-8673, 1095-8673
Online Access:	Get full text
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